A5089165157- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Reproductive System and Pregnancy
- Endometrial and Cervical Cancer Treatments
- Intestinal and Peritoneal Adhesions
- Gynecological conditions and treatments
- Estrogen and related hormone effects
- Selenium in Biological Systems
- Pregnancy-related medical research
- Ovarian cancer diagnosis and treatment
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Trace Elements in Health
- Cancer Risks and Factors
- Vitamin D Research Studies
- Heavy Metal Exposure and Toxicity
Rzeszów University
2020-2024
Fryderyk Chopin University of Music
2023
Abstract STUDY QUESTION Are there specific autoantibody profiles in patients with endometriosis that are different from those controls? SUMMARY ANSWER This study did not reveal a significantly higher prevalence of autoantibodies the studied groups patients. WHAT IS KNOWN ALREADY Various inflammatory factors postulated to be involved pathomechanisms endometriosis, and potential link exists autoimmune diseases, which may also play an important role. As diagnosis remains invasive, it can only...
An evaluation of the association between concentrations vitamin D-binding protein and lactoferrin in plasma peritoneal fluid may facilitate elucidation molecular mechanisms endometriosis. Vitamin were measured by ELISA samples from 95 women with suspected endometriosis as classified laparoscopy into groups (n = 59) without 36). There no differences (p > 0.05) In endometriosis, there was a significant correlation (r 0.821; p 0.000), but those compartments 0.049; 0.05). Furthermore, found...
The aim of this study was to investigate the relationship between lactoferrin and iron its binding proteins in women with endometriosis by simultaneously measuring these parameters plasma peritoneal fluid. Ninety were evaluated, whom 57 confirmed as having endometriosis. Lactoferrin measured ELISA, transferrin, ferritin on a Cobas 8000 analyser. transferrin fluid lower compared plasma, contrast iron. In showeds associations group without correlated lactoferrin, patients ratio concentration...
Laparoscopy as a diagnostic tool for patients with suspected endometriosis is associated several potentially life-threatening complications. Therefore, it imperative to identify reliable, non-invasive biomarkers of the disease. The aim this study was analyse concentrations fibronectin and type IV collagen in peritoneal fluid plasma assess their role potential diagnosis endometriosis. Fibronectin protein levels were assessed by surface plasmon resonance imaging (SPRi) biosensors usage...
Cadherin 12 (CDH 12) can play a role in the pathogenesis of endometriosis. The aim this study was to compare levels cadherin peritoneal fluid between women with and without This multicenter cross-sectional study. Eighty-two patients undergoing laparoscopic procedures were enrolled concentrations determined using enzyme-linked immunosorbent assay. level statistical significance set at p < 0.05. No differences endometriosis observed (p = 0.4). Subgroup analyses showed that CDH significantly...
Background: Available studies on the effect of serum selenium levels risk malignancies show some conflicting results. In this study, we investigated correlation between and ovarian cancer occurrence. Methods: 314 women (157 diseased patients 157 healthy ones) matched in terms age BMI were included study. The measurements collected blood samples performed using an ICP mass spectrometer. Univariable multivariable analyzes to determine relationship factors under study occurrence cancer....
Zinc finger E-box-binding homeobox 1 (ZEB1) and zinc 2 (ZEB2) are transcription factors that regulate epithelial−mesenchymal transformation (EMT). The aim of this study was to compare levels ZEB1 ZEB2 in the peritoneal fluid plasma between patients with without endometriosis order assess their utility diagnostic process. Plasma samples were collected from 50 48 during planned surgical procedures eight clinical centers. Quantitative analyses performed using a double-antibody sandwich...
Background The aim of this study was to analyze the concentration leptin in peritoneal fluid and plasma assess their role as potential biomarkers diagnosis endometriosis. Materials &amp; methods Leptin adjusted for BMI (leptin/BMI ratio) measured using surface plasmon resonance imaging (SPRI) biosensors. Patients with suspected endometriosis were included study. Plasma collected from 70 cases, 67 cases. Based on presence lesions detected during laparoscopy, patients divided into a group...
Background.Endometrial cancer is the most common malignant neoplasm of female reproductive organs.A dysfunctional endometrial renin-angiotensin system (RAS) might contribute to growth and spread cancer.The RAS-related gene polymorphisms, including polymorphism insertion/ deletion (I/D) in angiotensin-converting enzyme (ACE) gene, influence RAS activity.Objectives.In present study, we examined association between I/D ACE risk Polish women.Material methods.Genotype analysis was carried out...
The evidence of poly (ADP-ribose) polymerase (PARP) association with the immune response could be coherent immunological theory endometriosis and suggests possibility a new research direction. aim study was to evaluate levels PARP in plasma peritoneal fluid patients without endometriosis. It multicenter, cross-sectional study. Plasma samples were collected from during planned laparoscopic procedures eight clinical centers. In total, 84 included final analyses. Double-antibody sandwich...
Endometriosis is a chronic disease in which the endometrium cells are located outside uterine cavity. The aim of this study was to evaluate circulating 20S proteasome and immunoproteasome levels plasma peritoneal fluid women with without endometriosis order assess their usefulness as biomarkers disease. Concentrations were measured using surface plasmon resonance imaging biosensors. Patients suspected included study—plasma collected 112 cases 75. Based on presence lesions detected during...
Objectives: Obesity has been suggested to have a negative influence on procedural outcomes of endometrial cancer laparoscopic treatment. and other possible risk factors treatment not precisely described in the literature. The aim study is determine that greatest course surgery for cancer, with particular emphasis obesity. Material methods: included 75 females who were treated by surgery. Preoperative body-mass index (BMI), waist circumference(WC), hip ratio(WHR), selected anatomical indices...
Objectives: Abdominal obesity is a risk factor for endometrial cancer. The negative impact of individual parameters on the procedural effects cancer surgical treatment has been suggested. aim current study was to estimate relationship particular and in-hospital outcomes in patients treated surgically due Material methods: included 70 women Pre-operatively, mass, body mass index (BMI), waist circumference, waist-hip ratio selected anatomical indices were measured. duration surgery,...
Introduction: Endometriosis is an inflammatory-related reproductive age disease characterized by the presence of endometrial cells outside uterine cavity. Current laboratory practice does not provide specific markers for detecting and assessing advancement endometriosis in either plasma or peritoneal fluid. The severity assessed stages from I to IV based on results laparoscopic inspection. protein annexin A2 (ANXA2) has been reported be associated with inflammatory processes. Aim Study:...