Mariana Di Lorenzo

ORCID: 0000-0003-2829-0436
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Research Areas
  • Effects and risks of endocrine disrupting chemicals
  • Reproductive biology and impacts on aquatic species
  • Toxic Organic Pollutants Impact
  • Estrogen and related hormone effects
  • Environmental Toxicology and Ecotoxicology
  • Carcinogens and Genotoxicity Assessment
  • Zebrafish Biomedical Research Applications
  • Physiological and biochemical adaptations
  • Renal Transplantation Outcomes and Treatments
  • Ovarian function and disorders
  • Neurobiology and Insect Physiology Research
  • Nutritional Studies and Diet
  • Dialysis and Renal Disease Management
  • Consumer Attitudes and Food Labeling
  • Regulation of Appetite and Obesity
  • Growth Hormone and Insulin-like Growth Factors
  • Aquaculture Nutrition and Growth
  • Diet and metabolism studies
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Protein Hydrolysis and Bioactive Peptides
  • HIV, Drug Use, Sexual Risk
  • Dye analysis and toxicity
  • Muscle metabolism and nutrition
  • HIV-related health complications and treatments
  • Nutrition, Genetics, and Disease

University of Naples Federico II
2016-2025

University of Campania "Luigi Vanvitelli"
2023

Ospedale D. Cotugno
2022

Abstract Purpose of Review The goal the present review is to address main adiposity-related alterations in Polycystic Ovary Syndrome (PCOS) focusing on hypothalamic-pituitary-ovarian (H-P-O) axis and provide an overview nutraceutical pharmacological therapeutic strategies. Recent Findings Female reproduction a complex delicate interplay between neuroendocrine signals involving H-P-O axis. Elements that disrupt balance these interactions can lead metabolic reproductive disorders, such as...

10.1007/s13679-023-00531-2 article EN cc-by Current Obesity Reports 2024-01-03

The prevalence of chronic kidney disease (CKD) is rising, especially in elderly individuals. overlap between CKD and aging associated with body composition modification, metabolic abnormalities, malnutrition. Renal care guidelines suggest treating patient a low-protein diet according to the renal stage. On other hand, geriatric underline need for higher protein intake prevent challenge remains how reconcile low dietary insuring favorable nutritional status populations. Therefore, this study...

10.3390/nu16050632 article EN Nutrients 2024-02-24

The goal of this study was to evaluate P450 aromatase localization in the epididymis two different vertebrates: lizard Podarcis sicula, a seasonal breeder, and Rattus rattus, continuous breeder. is key enzyme involved local control spermatogenesis steroidogenesis we proved for first time that represented both P. sicula R. rattus. In details, well epithelial myoid cells connective tissue during reproductive period; instead, autumnal resumption absent tissue. During non-reproductive period,...

10.4081/ejh.2020.3080 article EN cc-by-nc European Journal of Histochemistry 2020-01-27

Background: Nonylphenol (NP) and Octylphenol (OP) are persistent non-biodegradable environmental contaminants classified as endocrine disruptor chemicals (EDCs). These compounds widely used in several industrial applications present estrogen-like properties, which have extensively been studied aquatic organisms. The study aimed to verify the interference of these alone, mixture, on reproductive cycle male terrestrial vertebrate Podarcis siculus, focusing mainly steroidogenesis process....

10.3390/ani11041003 article EN cc-by Animals 2021-04-02

Abstract Different environmental contaminants disturb the thyroid system at many levels. AlkylPhenols (APs), by-products of microbial degradation AlkylPhenol Polyethoxylates (APEOs), constitute an important class Endocrine Disrupting Chemicals (EDCs), two most often used APs being 4-nonylphenol (4-NP) and 4-tert-octylphenol (4-t-OP). The purpose present study was to investigate effects on gland bioindicator Podarcis siculus OP alone in combination with NP. We radioimmunoassay determine their...

10.1007/s00244-021-00823-5 article EN cc-by Archives of Environmental Contamination and Toxicology 2021-03-09

Fetal exposure to certain phthalate esters can disrupt testis development in rodents and lead male reproductive disorders, but with a causal link less humans. Di(2-ethylhexyl) (DEHP) is one of the most common phthalates found environment it known induce serious toxicity, as well disorders including cryptorchidism, hypospadias, impaired spermatogenesis reduced fertility. In this study, we show that perinatal DEHP disrupts gap junction localization fetal postnatal rat correlate these findings...

10.1016/j.crtox.2020.02.002 article EN cc-by-nc-nd Current Research in Toxicology 2020-03-10

Pollution is one of the main causes loss biodiversity, currently most important environmental problems. Important sources aquatic pollution are illicit drugs, whose presence in waters closely related to human consumption; their psychoactive properties and biological activity suggest potential adverse effects on non-target organisms, such as biota. In this study, we evaluated effect an environmentally relevant concentration cocaine (20 ng L−1), drug widely found surface waters, ovaries...

10.3390/ani12141766 article EN cc-by Animals 2022-07-10

One of the main culprits obesity epidemic is obesogenic food environment, which promotes consumption ultra-processed foods (UPFs) that are highly palatable, have low nutritional quality and a high caloric impact economical ready to use. This monocentric retrospective study explored association between UPFs, adiposity measurements among adults living with in Southern Italy.

10.3390/nu16223923 article EN Nutrients 2024-11-17

Cocaine is one of the most widely used illicit drugs in world, and as a result incomplete removal by sewage treatment plants it found surface waters, where represents new potential risk for aquatic organisms. In this study we evaluated influence environmental concentrations cocaine on liver kidney European eel (Anguilla anguilla). The eels were exposed to 20 ng L−1 fifty days, after which, three ten days interruption exposure their livers kidneys compared controls. general morphology two...

10.1016/j.ecoenv.2020.111475 article EN cc-by Ecotoxicology and Environmental Safety 2020-10-14

Abstract Introduction The aim of this study was to investigate how long hospitalized patients stayed positive the nasopharyngeal swab, and what demographic clinical factors influence time-to-negative swab. Methods We enrolled in a multicenter, observational, retrospective involving 17 COVID-19 units eight cities Campania, southern Italy all from March 2020 May 2021 diagnosed with Severe Acute Respiratory Distress Syndrome-Coronavirus-2 (SARS-CoV-2) infection for whom swab available. Results...

10.1007/s15010-023-02095-8 article EN cc-by Infection 2023-09-13

The abuse of artificial food dyes and the evidence that they harm human health recently prompted a significant effort to introduce vegan substitutes prepared from fruits vegetables. Not much information, however, has been collected on their possible effects aquatic terrestrial ecosystems once released as waste in surface waters. For this purpose, we analyzed red (VEG) preparation (concentration 1.2 g/L) three rapidly proliferating models for ecosystem contamination. In particular, vitro...

10.3390/environments9070089 article EN Environments 2022-07-10
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