A5017835877- Aquaculture disease management and microbiota
- Aquaculture Nutrition and Growth
- interferon and immune responses
- Invertebrate Immune Response Mechanisms
- Immune Response and Inflammation
- Antimicrobial Peptides and Activities
- Chemokine receptors and signaling
- Reproductive biology and impacts on aquatic species
- Fish Biology and Ecology Studies
- Immune Cell Function and Interaction
- Cancer-related molecular mechanisms research
- Physiological and biochemical adaptations
- Viral Infections and Vectors
- RNA regulation and disease
- IL-33, ST2, and ILC Pathways
- T-cell and B-cell Immunology
- Animal Virus Infections Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Mycobacterium research and diagnosis
- Epigenetics and DNA Methylation
- Aquatic life and conservation
- Animal Genetics and Reproduction
- Cancer-related gene regulation
- Animal Nutrition and Physiology
- Cytokine Signaling Pathways and Interactions
Yangtze University
2015-2024
Shantou University
2016-2021
Ministry of Agriculture and Rural Affairs
2019
China Fishery Machinery and Instrument Research Institute
2018
University of Aberdeen
2013-2018
Guangxi Institute of Oceanography
2018
Institute of Oceanology
2018
University of Padua
2018
Institute of Hydrobiology
2016
Chinese Academy of Sciences
2016
Abstract TNF-α is a cytokine involved in systemic inflammation and regulation of immune cells. It produced chiefly by activated macrophages as membrane or secreted form. In rainbow trout, two molecules were described previously. this article, we report third (TNF-α3) that has only low identities to known trout molecules. Phylogenetic tree synteny analyses other fish species suggest types (named I II) exist teleost fish. The type-II short stalk may impact on its enzymatic release restrict it...
IL-4 and IL-13 are closely related canonical type-2 cytokines in mammals have overlapping bioactivities via shared receptors. They frequently activated together as part of the same immune response signature produced by T-helper (Th)2 cells innate lymphoid (ILC2), mediating immunity against extracellular pathogens. Little is known about origin responses, whether they were an essential component early adaptive system that gave a fitness advantage limiting collateral damage caused metazoan...
An 8-week feeding trial was conducted to study the effect of long-term low-salinity stress on growth performance, and expression osmolarity metabolism-related genes (Na+-K+-ATPase α-subunit in gills, trypsin chymotypsin hepatopancreas) white shrimp (L. vannamei). Four groups (mean initial weight, 0.31 ± 0.02 g) were cultivated at salinity 2, 10, 20 30 psu for 8-week. All treatments triplicate 40 each. The results indicated that shrimps reared significantly higher final weight gain specific...
Mammalian IL-2 is a cytokine centrally involved in the differentiation and survival of CD4+ T helper subsets regulatory cells activation cytotoxic effector lymphocytes. In bony fish, IL2 orthologues have been identified with an additional divergent IL2-Like gene on same locus present several fish species. We report here two paralogues, IL2A IL2B, salmonids that originated from whole genome duplication event this lineage. The salmonid paralogues differ not only sequence but also exon sizes....
Background Interferon regulatory factor (IRF) 10 was first found in birds and is present the genome of other tetrapods (but not humans mice), as well teleost fish. The functional role IRF10 vertebrate immunity relatively unknown compared to IRF1-9. target this research clone characterize genes three economically important fish species that will facilitate future evaluation molecule innate adaptive immunity. Molecular Characterization Three Fish Species In study, a single gene cloned grass...
The chemokine receptors CXCR1–3 bind to 11 chemokines (CXCL1–11) that are clustered on the same chromosome in mammals but largely missing ray-finned fish. A second CXCR1/2, and a CXCR3a CXCR3b gene have been cloned rainbow trout. Analysis of CXCR1–R3 genes lobe-finned fish, fish tetrapod genomes revealed teleostomian ancestor likely possessed loci containing both CXCR1 CXCR2, CXCR3b. Based this synteny analysis first trout CXCR1/2 was renamed CXCR1, new CXCR2. CXCR1/R2 locus shown further...
Summary Gut microbiota could facilitate host to defense diseases, but fish–microbiota interactions during viral infection and the underlying mechanism are poorly understood. We examined responses of gut grass carp reovirus (GCRV) in Ctenopharyngodon idellus , which is most important aquaculture fish worldwide. found that GCRV group with serious haemorrhagic symptoms (G7s) showed considerably different microbiota, especially an abnormally high abundance gram‐negative anaerobic Cetobacterium...
Toll-like receptors (TLRs) are important pattern recognition (PRRs) which can recognize a series of pathogen associated molecular patterns (PAMPs) to initiate the host innate immune responses. In present study, two TLRs (TLR2 and TLR13) were identified for first time from endangered primitive-ray finned fish Dabry's sturgeon (Acipenser dabryanus), critically species. The full-length TLR2 was 2591 bp, including an open reading frame (ORF) 2394 bp encoded polypeptide 797 amino acids. adaTLR13...
Antimicrobial peptides (AMPs) are small proteins with broad-spectrum antimicrobial activities, and could kill a variety of pathogens. In this study, 50 mg/kg (G1 group), 100 (G2), 200 (G3) AMPs were added to the basal diet (0 AMPs, G0 group) largemouth bass (Micropterus salmoides). After feeding for 60 days, growth performance, muscle composition, activities antioxidase immune-related enzymes digestive enzymes, intestinal morphology M. salmoides measured. The results showed that final...
More and more diseases were occurred in the aquaculture of Asian swamp eel. Bacterial isolates collected from pathogenic organs diseased eels. A dominant strain, Aeromonas veronii JL-01, was isolated identified liver intestine tissue The symptoms fish infected artificially with A. same as those observed under natural infection. mortality rate 40%–80% eels died 2–3 days after Drug sensitivity tests showed that bacterium highly sensitive to seven kinds antibiotics, including cephalosporins,...
An 8-week feeding trial was conducted to investigate the effects of replacing dietary fish meal with enzyme-treated soybean (ETS) on growth performance, intestine microflora, immune response and disease resistance white shrimp, Litopenaeus vannamei (initial body weight: 1.5 ± 0.2 g). With replaced by 0%, 8%, 16%, 24%, 32%, 40% 48% ETS, respectively, seven isonitrogenous experimental diets were formulated. These named as Diet-0, Diet-8, Diet-16, Diet-24, Diet-32, Diet-40 Diet-48 respectively....