A5007167945- Aquaculture Nutrition and Growth
- Aquaculture disease management and microbiota
- interferon and immune responses
- Influenza Virus Research Studies
- Invertebrate Immune Response Mechanisms
- Crustacean biology and ecology
- Aquatic life and conservation
- Physiological and biochemical adaptations
- HIV Research and Treatment
- Animal Disease Management and Epidemiology
- MicroRNA in disease regulation
- HIV/AIDS drug development and treatment
- Protein Hydrolysis and Bioactive Peptides
- Animal Nutrition and Physiology
- Immune Response and Inflammation
- Animal Virus Infections Studies
- Antimicrobial Peptides and Activities
- Reproductive biology and impacts on aquatic species
- Medical Research and Treatments
- Immune Cell Function and Interaction
- Viral gastroenteritis research and epidemiology
- Cytokine Signaling Pathways and Interactions
- Fish Biology and Ecology Studies
- Neurobiology and Insect Physiology Research
- RNA Interference and Gene Delivery
Yangtze University
2015-2024
Chinese Academy of Fishery Sciences
2024
Yanshan University
2024
Guangdong Ocean University
2024
Affiliated Hospital of Shaanxi University of Chinese Medicine
2018-2023
China Agricultural University
2016-2022
Ministry of Agriculture and Rural Affairs
2022
Guangxi Institute of Oceanography
2018
Institute of Oceanology
2018
Institute of Agro-Products Processing Science and Technology
2017
The present study was conducted to investigate the effect of fish meal replacement with Clostridium autoethanogenum protein (CAP) on growth performance, haemato-biochemistry, digestive capacity, antioxidant index, and histopathological examination liver intestine in largemouth bass (Micropterus salmoides). Seven experimental diets were formulated CAP 0% (CAP0), 15% (CAP15), 27% (CAP27), 39% (CAP39), 51% (CAP51), 63% (CAP63) 75% (CAP75) meal, respectively. Results showed that by did not...
Adaptation of the viral polymerase complex comprising PB1, PB2, and PA is necessary for efficient influenza A virus replication in new host species. We found that mutation K356R (PA-K356R) has become predominant since 2014 avian H9N2 viruses China as with seasonal human H1N1 viruses. The same also most isolates emergent H7N9 H10N8 whose six internal gene segments are derived from virus. further demonstrated mammalian adaptive functionality PA-K356R mutation. Avian A549 cells showed increased...
An 8-week feeding trial was conducted to study the effect of long-term low-salinity stress on growth performance, and expression osmolarity metabolism-related genes (Na+-K+-ATPase α-subunit in gills, trypsin chymotypsin hepatopancreas) white shrimp (L. vannamei). Four groups (mean initial weight, 0.31 ± 0.02 g) were cultivated at salinity 2, 10, 20 30 psu for 8-week. All treatments triplicate 40 each. The results indicated that shrimps reared significantly higher final weight gain specific...
Since May 2014, highly pathogenic avian influenza H5N6 virus has been reported to cause six severe human infections three of which were fatal. The biological properties this subtype, in particular its relative pathogenicity and transmissibility mammals, are not known. We characterized the receptor-binding affinity, pathogenicity, mice ferrets four isolates derived from waterfowl China 2013-2014. All viruses have acquired a binding affinity for human-like SAα2,6Gal-linked receptor be able...
ABSTRACT Segment reassortment and base mutagenesis of influenza A viruses are the primary routes to rapid evolution high-fitness virus genotypes. We recently described a predominant G57 genotype avian H9N2 that caused countrywide outbreaks in chickens China during 2010 2013, which led zoonotic emergence H7N9 viruses. One key features is replacement earlier A/chicken/Beijing/1/1994 (BJ/94)-like M gene with A/quail/Hong Kong/G1/1997 (G1)-like quail origin. report here functional significance...
H9N2 Avian influenza virus (AIV) is regarded as a principal donor of viral genes through reassortment to co-circulating viruses that can result in zoonotic reassortants. Whether maintain sustained evolutionary impact on such reassortants unclear. Since 2013, avian H7N9 had caused five sequential human epidemics China; the fifth wave 2016-2017 was by far largest but mechanistic explanation behind scale infection not clear. Here, we found that, just prior epidemic, phylogenetically mutated...
Background: The orphan G protein-coupled receptor (GPR) 39 was originally identified as the of obestatin. In this study, effects and mechanisms GPR39 on cell proliferation differentiation were investigated in cultured porcine intramuscular preadipocytes. Methods: Morphology preadipocytes accumulated lipid droplets within cells by an inverted microscope. After transfected with constructed pCMV-GPR39 plasmid, measured using methyl thiazolyl tetrazolium method, mRNA expression GPR39,...
Adaptation of PB2 protein is important for the establishment avian influenza viruses in mammalian hosts. Here, we identify I292V as prevalent mutation circulating H9N2 and pandemic H1N1 viruses. The same dominant also found most human isolates emergent H7N9 H10N8 In cells, PB2-292V virus has combined ability conferring higher viral polymerase activity stronger attenuation IFN-β induction than that its predecessor PB2-292I. accompanied by binding affinity host mitochondrial antiviral...
The H10 subtype of avian influenza viruses (AIVs) circulates globally in wild birds and poultry, this has been shown to be increasingly prevalent China. Among the various viruses, H10N7 AIVs have caused repeated mammal human infections. To investigate their genetic adaptation mammals, we generated a mouse-adapted variant (A/mallard/Beijing/27/2011-MA; BJ27-MA) which exhibited increased virulence mice compared wild-type virus acquired neurotropism. Sequencing showed absence widely recognized...
A 12-week feeding trial was conducted to evaluate the effects of replacement dietary fish oil by rapeseed on growth, anti-oxidative capacity and inflammatory responses large yellow croaker Larimichthys crocea (initial body weight: 36.02 ± 0.58 g). The control diet designed contain 6.5% oil, named as FO. Based it, 50% 100% replaced make other two diets (FR RO, respectively). Results showed that specific growth rate significantly reduced, crude lipid contents in muscle liver were increased RO...
To explore the effects of dietary histidine on growth, non-specific immune and ovarian development red swamp crayfish (Procambarus clarkii), (5.98 ± 0.11 g) were fed six isoproteic isoenergetic diets with levels (3.90 (control), 5.67, 8.42, 10.57, 12.32, 15.02 g/kg) for eight weeks. The results showed that nearly all tested indicators demonstrated significant linear or quadratic trends variation levels. Weight gain rate (WGR), feed conversion ratio (FCR), protein efficiency (PER), deposition...
This study investigated the effects of dietary lysolecithin on growth performance, feed utilization and metabolic responses channel catfish (Ictalurus punctatus). Fish (initial weight: 14.77 ± 0.45 g) were randomly fed one five practical diets supplemented with graded levels (0, 125, 250, 375 500 mg/kg) in quadruplicate groups for 10 weeks. Results showed that no significant differences weight gain, condition factor viscerosomatic index among all treatments. diet 250 mg/kg had significantly...
The present study was conducted to investigate the effects of Antarctic krill Euphausia superba meal replacing dietary fish on growth performance, immunity and muscle quality white shrimp Litopenaeus vannamei (initial body weight: 4.080 ± 0.143 g, mean±SD). replacement levels were designed as 0%, 5%, 15%, 30%, 45%, 60%, 75% 100%, respectively. After a 52-day feeding trial, results showed that specific rate (P = 0.129) feed intake 0.217) not significantly affected. Feed conversion ratio (FCR,...