A5017627477- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Resistance in Bacteria
- Microbial infections and disease research
- Pharmaceutical and Antibiotic Environmental Impacts
- Zoonotic diseases and public health
- Animal Disease Management and Epidemiology
- COVID-19 epidemiological studies
- SARS-CoV-2 and COVID-19 Research
- Animal Diversity and Health Studies
- Salmonella and Campylobacter epidemiology
- Coccidia and coccidiosis research
- Vector-borne infectious diseases
- Drug Transport and Resistance Mechanisms
- Pesticide Residue Analysis and Safety
- Viral gastroenteritis research and epidemiology
- Animal Nutrition and Physiology
- Veterinary medicine and infectious diseases
- Animal Virus Infections Studies
- Electrolyte and hormonal disorders
- Analytical Methods in Pharmaceuticals
- Plant Pathogenic Bacteria Studies
- Viral Infections and Vectors
- Pharmacological Effects and Assays
- Veterinary Practice and Education Studies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
Jordan University of Science and Technology
2016-2025
American College of Veterinary Surgeons
2023
The University of Queensland
2023
University of Pisa
2023
Washington State University
2023
North Carolina State University
2023
London School of Hygiene & Tropical Medicine
2021
National Institute of Allergy and Infectious Diseases
2021
National Institutes of Health
2021
Royal Veterinary College
2021
The death toll and economic loss resulting from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic are stark reminders that we vulnerable to zoonotic viral threats. Strategies needed identify characterize animal viruses pose greatest risk of spillover spread in humans inform public health interventions. Using expert opinion scientific evidence, identified host, viral, environmental factors contributing virus humans. We then developed a ranking framework interactive web...
Avian pathogenic Escherichia coli (APEC) is the principle cause of colibacillosis affecting poultry. The main challenge to poultry industry antimicrobial resistance and emergence multidrug resistant bacteria that threaten safety food chain. Risk factors associated with among avian E. were correlated inappropriate use antimicrobials along inadequate hygienic practices, which encourages selection pressure APEC. aim this study was isolate, identify, serogroup genotype APEC from broilers, assess...
Abstract The World Health Organization describes brucellosis as one of the world’s leading zoonotic diseases, with Middle East a global hotspot. Brucella melitensis is endemic among livestock populations in region, transmission occurring via consumption raw milk, amongst other routes. Control largely vaccination small ruminant and cattle populations. Due to sociocultural religious influences camel milk ( camelus dromedarius) widely consumed raw, while from species boiled. To investigate...
The effect of tilmicosin, florfenicol, or enrofloxacin on humoral and cell-mediated immune response induced by Newcastle disease (ND) vaccination was evaluated in 20-wk-old specific-pathogen-free layer chickens. Humoral immunity measured detection ND virus (NDV) antibody titer anti-NDV IgG using the hemagglutination inhibition (HI) test ELISA, respectively, whereas measurement chicken interferon gamma (ChIFN-gamma) produced splenocytes cell culture stimulated with concanavalin A, inactivated...
Prevalence of Middle East respiratory syndrome coronavirus (MERS-CoV) was determined in 45 dromedary camels from two geographically separated herds Jordan. Virus shedding only detected swabs obtained the tract and primarily observed younger than 3 years. MERS-CoV seroprevalence increased with age camels. Bovine sheep sera were seronegative. Phylogenetic analysis partial S2 clustered Jordanian strains contemporary associated nosocomial outbreaks.
The effects of thermal manipulation (TM) at 38.5°C and 40°C for 6 h embryonic day (ED) 16, 9 ED 17, 12 18 on body weight (BW) cloacal temperature (Tb) during the first wk later post-hatch d 10, 14, 21, 28, 42 were evaluated. Furthermore, chicks' ability to cope with a challenge (TC; 41°C h) 14 was also A chick's response TC measured by determining temperature; plasma thyroid hormones (thyroxin (T4) triiodothyronine (T3)); packed cell volume (PCV); heterophil (H), lymphocyte (L), monocyte,...
Abstract Host-virus associations have co-evolved under ecological and evolutionary selection pressures that shape cross-species transmission spillover to humans. Observed virus-host provide relevant context for newly discovered wildlife viruses assess knowledge gaps in host-range estimate pathways potential human infection. Using models predict networks, we predicted the likelihood of humans as hosts 513 detected by large-scale surveillance at high-risk animal-human interfaces Africa, Asia,...
Leptospirosis, caused by Leptospira spp., affects humans and animals, posing significant health economic burdens. This multidisciplinary One Health study aimed to estimate the prevalence of spp.-specific antibodies in livestock at human-animal interfaces Jordan. Study sites were selected across Jordan based on previous research showing a high likelihood zoonotic pathogen circulation. The population comprised 500 individuals 400 (sheep, goats, cattle, camels). Blood samples collected from...
Middle East respiratory syndrome coronavirus (MERS-CoV) is an important zoonotic pathogen. The aim of this paper to report one polymerase chain reaction (PCR)-positive case MERS-CoV in a 27-year-old man who was involved nationwide longitudinal surveillance study certain diseases Jordan including MERS-CoV. Whole-blood and nasal swab samples were collected from the five camels vicinity his living area. subjected enzyme-linked immunosorbent assay (ELISA) real-time reverse-transcription PCR...
Abstract Q fever represents an important ‘neglected zoonosis’, with high prevalences recorded across the Middle East region. Among rural desert‐dwelling communities in region, camel milk is largely consumed raw, due to perceptions of dromedaries as a uniquely clean livestock species mentioned Qur'an and Islamic hadith, while from other usually boiled. As result, camels present unique public health threat among such milk‐borne pathogens, including Coxiella burnetii. In view this,...
The pharmacokinetics and oral bioavailability of two tylosin formulations was carried out in broiler chickens according to a single dose, randomized, parallel design. (Tylosina® Tylan®) were given orally at dose level 25 mg/kg b.w. after an overnight fasting (n=15 chicken/group). To calculate bioavailability, fifteen more assigned as group 3 intravenous (25 b.w.). Serial blood samples collected different time points up 24 hour post-drug administration. A high performance liquid...
Avian colibacillosis is an infectious disease of chickens caused by avian pathogenic Escherichia coli (APEC). Respiratory viruses and Mycoplasma infections cause damage to the respiratory system predispose them APEC. The APEC field isolates have begun showing increased antimicrobial resistance, leading failure treatment increasing costs production losses. objective this study was investigate susceptibility different combinations using minimum inhibitory concentration checkerboard tests. All...
A bioavailability and pharmacokinetics study of doxycycline was carried out on 30 healthy ostriches after a single intravenous (IV), intramuscular (IM) oral dose 15 mg/kg body weight.The plasma concentration determined by HPLC/UV at 0 (pretreatment), 0.08, 0.25, 0.5 1, 2, 4, 6, 8, 12, 24 48 h administration.The concentration-time curves were examined using non-compartmental methods based the statistical moment theory for only higher dose.After IV administration, elimination half-life (t 1/2β...
A pharmacokinetic and bioavailability study of sulfadiazine combined with trimethoprim (sulfadiazine/trimethoprim) was carried out in fifteen healthy young ostriches after intravenous (i.v.), intramuscular (i.m.) oral administration at a total dose 30 mg/kg body weight (bw) (25 5 bw trimethoprim, respectively). The followed single dose, three periods, cross-over randomized design. sulfadiazine/trimethoprim combination administered to an overnight fasting on treatment days, each separated by...
A pharmacokinetic and bioavailability study of spectinomycin was conducted in healthy broiler chickens following administration a single (50 mg/kg bw) intravenous (i.v.), intramuscular (i.m.) subcutaneous (s.c.) dose oral doses 50 100 bw. Following i.v. administration, the elimination half‐life ( t 1/2 β ), mean residence time MRT volume distribution at steady‐state V d(ss) based on terminal phase d(z) ) total body clearance Cl B were 1.46 ± 1.10 h, 1.61 1.05 0.26 0.009 L/kg, 0.34...