Tapan N. Dhole

ORCID: 0000-0002-5633-3424
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Research Areas
  • Mosquito-borne diseases and control
  • Viral Infections and Vectors
  • Vector-borne infectious diseases
  • HIV Research and Treatment
  • Mycobacterium research and diagnosis
  • Tuberculosis Research and Epidemiology
  • Immune Cell Function and Interaction
  • Infectious Diseases and Tuberculosis
  • Diagnosis and treatment of tuberculosis
  • Neuroinflammation and Neurodegeneration Mechanisms
  • T-cell and B-cell Immunology
  • HIV/AIDS drug development and treatment
  • Viral Infections and Immunology Research
  • Drug Transport and Resistance Mechanisms
  • interferon and immune responses
  • Respiratory viral infections research
  • Pneumonia and Respiratory Infections
  • Influenza Virus Research Studies
  • MicroRNA in disease regulation
  • Protease and Inhibitor Mechanisms
  • Immune Response and Inflammation
  • Inflammasome and immune disorders
  • Pharmacological Effects and Toxicity Studies
  • Malaria Research and Control
  • Otolaryngology and Infectious Diseases

Sanjay Gandhi Post Graduate Institute of Medical Sciences
2014-2023

University of Lucknow
2020

Institute of Medical Sciences
2020

King George's Medical University
2001-2019

University College of Medical Sciences
2016

Centre of Biomedical Research
2016

Babasaheb Bhimrao Ambedkar University
2013

Public Health Foundation of India
2013

Dr. V. M. Government Medical College
1982

Objective/background: Nontuberculous mycobacteria (NTM) infection associated with pulmonary and extrapulmonary disease has been increasing globally. Despite an increase in incidence rate of NTM infection, its prevalence, species diversity, circulation pattern India is largely unknown. This study sought to investigate the overall burden diversity among both clinical isolates from a Northern Indian population. Methods: The was conducted Department Microbiology, January 2013 December 2015. A...

10.1016/j.ijmyco.2016.06.008 article EN cc-by-nc-nd International Journal of Mycobacteriology 2016-06-28
Natalie I Mazur Yvette N. Löwensteyn Joukje E. Willemsen Christopher Gill Leah S. Forman and 95 more Lawrence Mwananyanda Dianna M. Blau Robert F. Breiman Shabir A. Madhi Sana Mahtab Emily S. Gurley Shams El Arifeen Nega Assefa J. Anthony G. Scott Dickens Onyango Beth A. Tippet Barr Karen L. Kotloff Samba O. Sow Inácio Mandomando Ikechukwu U. Ogbuanu Amara Jambai Quique Bassat Somsak Thamthitiwat Ángela Gentile María Florencia Luciön Márcia Rosane Pires Fernanda de Paris Aubree Gordon Félix Sánchez Marilla Lucero Socorro Lupisan Bradford D. Gessner Haoua Tall Natasha Halasa Najwa Khuri‐Bulos D. James Nokes Patrick K. Munywoki Grieven P. Otieno Katherine L. O’Brien Katherine L Oshitani María Tereza da Costa Oliveira Carla Cecília de Freitas Lázaro Emediato Asad Ali Uzma Bashir Aamir Daniel E. Noyola Cheryl Cohen Jocelyn Moyes H. I. G. GIAMBERARDINO Jane Melissa Webler Patrícia Gomes de Matos Bezerra Maria do Carmo Menezes Bezerra Duarte Helen Y. Chu Rashmi Ranjan Das Martin W. Weber Nusrat Homaira Adam Jaffé Katharine Sturm‐Ramirez Wei Su Chiang Chun Yuan Sandra S. Chaves Gideon O. Emukule Sérgio de Andrade Nishioka Felipe Cotrim de Carvalho Şule Gökçe Sônia Mara Raboni Michael Hawkes Mélina Messaoudi Juliet E. Bryant Ghassan Dbaibo Rima Hanna‐Wakim Jayaweera Arachchige Asela Sampath Jayaweera K. A. Stolyarov Piyarat Suntarattiwong Tufária Mussá Alfredo Bruno Doménica de Mora Nasamon Wanlapakorn Zheng Xie Junhong Ai Jenny Ojeda L. Lucas Zamora Evangeline Obodai John Kofi Odoom Maha Talaat Ismail Andrea G. Buchwald Cristina O’Callaghan‐Gordo Jaime Fernández‐Sarmiento Evelyn Obando-Belalcazar Tapan N. Dhole Sheetal Verma Aykut Eşki G Ozturk Kartal Mohammed Al Amad Abdul Wahed Al Serouri Yoke FunChan Jamal I-Ching Sam Daniel Jarovsky Daniella Gregória Bomfim Prado da Silva Jose Gareca Pérales Teck‐Hock Toh

Respiratory syncytial virus (RSV) is a leading cause of pediatric death, with >99% mortality occurring in low- and lower middle-income countries. At least half RSV-related deaths are estimated to occur the community, but clinical characteristics this group children remain poorly characterized.The RSV Global Online Mortality Database (RSV GOLD), global registry under-5 who have died illness, describes dying through data sharing. GOLD acts as collaborative platform for deaths, including...

10.1093/cid/ciab528 article EN cc-by Clinical Infectious Diseases 2021-06-07

In India, quality surveillance for acute encephalitis syndrome (AES), including laboratory testing, is necessary understanding the epidemiology and etiology of AES, planning interventions, developing policy. We reviewed AES data January 2011-June 2012 from Kushinagar District, Uttar Pradesh, India. Data were cleaned, incidence was determined, demographic characteristics cases analyzed. A total 812 case records identified, which 23% had illogical entries. highest among boys<6 years age,...

10.3201/eid1909.121855 article EN cc-by Emerging infectious diseases 2013-07-29

ABSTRACT Background: Mycobacterium tuberculosis complex (MTBC) and non-tuberculous mycobacteria (NTM) may or not have same clinical presentations, but the treatment regimens are always different. Laboratory differentiation between MTBC NTM by routine methods time consuming cumbersome to perform. We evaluated role of GenoType® common mycobacteria/additional species (CM/AS) assay for different in isolates from (TB) cases. Materials Methods: A total 1080 specimens were collected January 2010...

10.4103/0974-2727.119847 article EN Journal of Laboratory Physicians 2013-07-01

Abstract Host-virus associations have co-evolved under ecological and evolutionary selection pressures that shape cross-species transmission spillover to humans. Observed virus-host provide relevant context for newly discovered wildlife viruses assess knowledge gaps in host-range estimate pathways potential human infection. Using models predict networks, we predicted the likelihood of humans as hosts 513 detected by large-scale surveillance at high-risk animal-human interfaces Africa, Asia,...

10.1038/s42003-022-03797-9 article EN cc-by Communications Biology 2022-08-19

Influenza A and Respiratory Syncytial Virus (RSV) has been recognized as a major cause of acute respiratory tract infection. H1N1 is one the subtypes influenza A, pandemic worldwide in July 2009, causing 18,449 deaths globally. To investigate prevalence clinical manifestation H1N1pdm09, RSV. Throat/nasal swab collected from patients all age group either outpatients/inpatients having illness 2 to 5 days. The data were recorded predesigned questionnaire. RNA was extracted analyzed by real time...

10.1002/jmv.24607 article EN Journal of Medical Virology 2016-06-22

Japanese Encephalitis (JE) has caused repeated outbreaks in endemic pockets of India. This study was conducted Kushinagar, a highly district, to understand the human-animal-ecosystem interactions, and drivers that influence disease transmission. Utilizing ecosystems approach, cross-sectional, descriptive study, employing mixed methods design employed. Four villages (two with pig-rearing two without) were randomly selected from high, medium low burden (based on case counts) block Kushinagar....

10.1371/journal.pone.0175745 article EN cc-by PLoS ONE 2017-05-02

Japanese encephalitis virus (JEV), a mosquito borne pathogen, is one of the major causes viral in eastern Uttar Pradesh, India. The objective this work was to evaluate entomological based virological surveillance (JE) highly endemic area Pradesh.The study carried out during September 2010 March 2013 Gorakhpur district Pradesh. A total 251 adult pools and 64 water samples containing larvae were collected from District Gorakhpur. Water pH, turbidity, oxygen level analyzed for vector breeding...

10.4103/0972-9062.172829 article EN cc-by-nc-sa Journal of Vector Borne Diseases 2015-01-01

Abstract The relationships between host immune factors and HIV‐1 disease progression are still in dispute. RANTES SNPs exhibit distinct ethnic distribution associated with different effects on the course of HIV infection. Therefore, impact gene polymorphism transmission needs to be evaluated. genotypes were identified by PCR‐RFLP method confirmed sequencing seronegative (HSN; n = 315), exposed (HES; 47) seropositive (HSP; 196) patients classified into clinical stages (i.e. Stages I, II,...

10.1002/jmv.21201 article EN Journal of Medical Virology 2008-05-06

Abstract Background Diagnosis of amoebic liver abscess (ALA) in patients on anti-amoebic drugs is difficult. There scanty data this issue using Entamoeba histolytica ( E. ) lectin antigen and polymerase chain reaction (PCR). We studied utility antigen, PCR, IgG antibody diagnosis treatment. Liver aspirate 200 patients, which 170 had drug prior to drainage, was tested for by (ELISA), bacterial culture, serum (ELISA). Classification abscesses based result PCR culture. Findings Using 136/200...

10.1186/1756-0500-5-416 article EN cc-by BMC Research Notes 2012-08-07
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