Alok Kumar

ORCID: 0000-0003-3717-7435
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About
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Research Areas
  • Supply Chain and Inventory Management
  • Innovation Diffusion and Forecasting
  • Customer Service Quality and Loyalty
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Mosquito-borne diseases and control
  • Sustainable Supply Chain Management
  • Consumer Retail Behavior Studies
  • Global Maternal and Child Health
  • Amyotrophic Lateral Sclerosis Research
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Innovation and Knowledge Management
  • Technology Adoption and User Behaviour
  • Consumer Market Behavior and Pricing
  • Agricultural Economics and Practices
  • SARS-CoV-2 and COVID-19 Research
  • Complex Systems and Decision Making
  • S100 Proteins and Annexins
  • Parasitic infections in humans and animals
  • Business Strategy and Innovation
  • Mitochondrial Function and Pathology
  • Cerebrospinal fluid and hydrocephalus
  • Autophagy in Disease and Therapy
  • Pesticide Exposure and Toxicity
  • Spinal Cord Injury Research
  • SARS-CoV-2 detection and testing

Fore School of Management
2016-2025

Sir Padampat Singhania University
2023-2025

Banaras Hindu University
2013-2024

Sanjay Gandhi Post Graduate Institute of Medical Sciences
2008-2024

KIST Medical College
2023-2024

Rabindranath Tagore International Institute of Cardiac Sciences
2024

Kalasalingam Academy of Research and Education
2024

Vignan's Foundation for Science, Technology & Research
2024

Chandra Shekhar Azad University of Agriculture and Technology
2024

Central Agricultural University
2024

Recent clinical studies indicate that traumatic brain injury (TBI) produces chronic and progressive neurodegenerative changes leading to late neurologic dysfunction, but little is known about the mechanisms underlying such changes. Microglial-mediated neuroinflammationis an important secondary mechanism after TBI. In human studies, microglial activation has been found persist for many years initial trauma, particularly moderate severe present study, adult C57Bl/6 mice were subjected single...

10.1097/nen.0000000000000021 article EN Journal of Neuropathology & Experimental Neurology 2013-12-12

Activated microglia and macrophages exert dual beneficial detrimental roles after central nervous system injury, which are thought to be due their polarization along a continuum from classical pro-inflammatory M1-like state an alternative anti-inflammatory M2-like state. The goal of the present study was analyze temporal dynamics microglia/macrophage within lesion micro-environment following traumatic brain injury (TBI) using moderate-level controlled cortical impact (CCI) model in mice. We...

10.1089/neu.2015.4268 article EN Journal of Neurotrauma 2015-10-21

Local and systemic inflammatory responses are initiated early after traumatic brain injury (TBI), may play a key role in the secondary processes resulting neuronal loss neurological deficits. However, mechanisms responsible for rapid expansion of neuroinflammation its long-term progression have yet to be elucidated. Here, we investigate microparticles (MP), member extracellular vesicle family, exchange pro-inflammatory molecules between immune cells, as well their transfer circulation,...

10.1186/s12974-017-0819-4 article EN cc-by Journal of Neuroinflammation 2017-03-06

Experimental spinal cord injury (SCI) causes chronic neuropathic pain associated with inflammatory changes in thalamic regulatory sites. Our recent studies examining mechanisms after rodent SCI showed not only thalamus, but also other regions including hippocampus and cerebral cortex. Because appeared similar to those our TBI models that are neurodegeneration neurobehavioral dysfunction, we examined effects of mouse on cognition, depressive-like behavior, brain inflammation. caused spatial...

10.1523/jneurosci.5110-13.2014 article EN Journal of Neuroscience 2014-08-13
Manoj Murhekar Tarun Bhatnagar Sriram Selvaraju V. Saravanakumar Jeromie Wesley Vivian Thangaraj and 95 more Naman K. Shah Muthusamy Santhosh Kumar Kiran Rade R. Sabarinathan Smita Asthana Rakesh Balachandar Sampada Dipak Bangar Avi Kumar Bansal Jyothi Bhat Vishal Chopra Dasarathi Das Alok Kumar Deb Kangjam Rekha Devi Gaurav Raj Dwivedi Muhammad Salim Khan C. P. Girish Kumar M. Sunil Kumar Avula Laxmaiah Major Madhukar Amarendra Mahapatra Suman Sundar Mohanty Chethana Rangaraju Alka Turuk Dinesh Kumar Baradwaj Ashrafjit S. Chahal Falguni Debnath Inaamul Haq Arshad Kalliath Srikanta Kanungo Jaya Singh Kshatri Gangeti Gandhi Jayanthi Naga Lakshmi Anindya Mitra A. Nirmala Ganta Venkata Prasad Mariya Amin Qurieshi Seema Sahay Ramesh Kumar Sangwan Krithikaa Sekar Vijay K. Shukla Prashant Kumar Singh Pushpendra Singh Rajeev Singh Dantuluri Sheethal Varma Ankit Viramgami Samiran Panda D. C. S. Reddy Balram Bhargava Rushikesh Andhalkar Anshuman Chaudhury Hirawati Deval Sarang Dhatrak Rajeev Ranjan Gupta Ezhilarasan Ilayaperumal Babu Jagjeevan Ramesh Chandra Jha K Kiran Nivethitha N. Krishnan Alok Kumar VG Vinoth Kumar K. Nagbhushanam Nimmathota Arlappa Ashok Kumar Pandey Harpreet Singh Pawar Kushal Singh Rathore Aby Robinson Hari Bhan Singh Vimith Cheruvathoor Wilson Ashwini Yadav Suresh Yadav T. Karunakaran Josephine Pradhan Tharsan Sivakumar Annamma Jose K Kalaiyarasi Sauvik Dasgupta R Anusha Tanu Anand Giridhara R. Babu Himanshu Chauhan Tanzin Dikid Raman Gangakhedkar Shashi Kant Sanket Kulkarni J. Muliyil Ravindra Mohan Pandey Swarup Sarkar Aakash Shrivastava Sujeet Kumar Singh Sanjay Zodpey Aparup Das Pradeep Das Shanta Dutta Rajni Kant Kanwar Narain Somashekar Narasimhaiah

BackgroundThe first national severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serosurvey in India, done May–June, 2020, among adults aged 18 years or older from 21 states, found a SARS-CoV-2 IgG antibody seroprevalence of 0·73% (95% CI 0·34–1·13). We aimed to assess the more recent nationwide general population India.MethodsWe did second household individuals 10 same 700 villages wards within 70 districts India that were included serosurvey. Individuals younger than and...

10.1016/s2214-109x(20)30544-1 article EN cc-by-nc-nd The Lancet Global Health 2021-01-27
Manoj Murhekar Tarun Bhatnagar Jeromie Wesley Vivian Thangaraj V. Saravanakumar Muthusamy Santhosh Kumar and 95 more Sriram Selvaraju Kiran Rade C. P. Girish Kumar R. Sabarinathan Alka Turuk Smita Asthana Rakesh Balachandar Sampada Dipak Bangar Avi Kumar Bansal Vishal Chopra Dasarathi Das Alok Kumar Deb Kangjam Rekha Devi Vikas Dhikav Gaurav Raj Dwivedi Muhammad Salim Khan M. Sunil Kumar Avula Laxmaiah Major Madhukar Amarendra Mahapatra Chethana Rangaraju Jyotirmayee Turuk Rajiv Yadav Rushikesh Andhalkar K. Arunraj Dinesh Kumar Bharadwaj Pravin Bharti Debdutta Bhattacharya Jyothi Bhat Ashrafjit S. Chahal Debjit Chakraborty Anshuman Chaudhury Hirawati Deval Sarang Dhatrak R. S. Dayal D. Elantamilan Prathiksha Giridharan Inaamul Haq Ramesh Kumar Hudda Babu Jagjeevan Arshad Kalliath Srikanta Kanungo Nivethitha N. Krishnan Jaya Singh Kshatri Alok Kumar Niraj Kumar Virendra Kumar Gangeti Gandhi Jayanthi Naga Lakshmi Ganesh Mehta Nandan Kumar Mishra Anindya Mitra K. Nagbhushanam Nimmathota Arlappa A. Nirmala Ashok Kumar Pandey Ganta Venkata Prasad Mariya Amin Qurieshi Sirasanambatti Devarajulu Reddy Aby Robinson Seema Sahay Rochak Saxena Krithikaa Sekar Vijay K. Shukla Hari Bhan Singh Prashant Kumar Singh Pushpendra Singh Rajeev Singh Nivetha Srinivasan Dantuluri Sheethal Varma Ankit Viramgami Vimith Cheruvathoor Wilson Surabhi Yadav Suresh Yadav Kamran Zaman Amit Chakrabarti Aparup Das Rupinder Singh Dhaliwal Shanta Dutta Rajni Kant Anam Khan Kanwar Narain Somashekar Narasimhaiah Chandrasekaran Padmapriyadarshini Krishna Pandey Sanghamitra Pati Shripad A. Patil Hemalatha Rajkumar Tekumalla Ramarao Y.K. Sharma Shalini Singh Samiran Panda D. C. S. Reddy Balram Bhargava Tanu Anand Giridhara R. Babu

BackgroundEarlier serosurveys in India revealed seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) 0.73% May–June 2020 and 7.1% August–September 2020. A third serosurvey was conducted between December January 2021 to estimate the SARS-CoV-2 infection among general population healthcare workers (HCWs) India.MethodsThe same 70 districts as first second serosurveys. For each district, at least 400 individuals aged ≥10 years from 100 HCWs subdistrict-level health...

10.1016/j.ijid.2021.05.040 article EN cc-by-nc-nd International Journal of Infectious Diseases 2021-05-19

Internet-based business-to-business platforms involve a buyer side transacting with seller side, both of which are customers an intermediary platform firm. Dyadic viewpoints implicit in conventional theories customer orientation thus must be modified to apply triadic relationship system (seller–platform–buyer) settings. The authors propose that firms consists total (customer toward the and sides) asymmetry favor relative side) examine antecedents consequences these orientations. Data from...

10.1509/jm.12.0442 article EN Journal of Marketing 2014-06-10

Lysosomal membrane permeabilization (LMP) is observed under many pathological conditions, leading to cellular dysfunction and death. However, the mechanisms by which lysosomal membranes become leaky in vivo are not clear. Our data demonstrate that LMP occurs neurons following controlled cortical impact induced (CCI) traumatic brain injury (TBI) mice, impaired macroautophagy (autophagy) neuronal cell Comparison of LC-MS/MS lipid profiles from TBI sham animals suggested a role for...

10.1080/15548627.2019.1628538 article EN cc-by-nc-nd Autophagy 2019-06-25

We examine transaction governance in the context of concurrent sourcing, where a manufacturer relies on sourcing from external suppliers and in‐house production simultaneously. Our focus is (1) buyer's use particular safeguards or mechanisms vis‐à‐vis an supplier (2) how effects these various performance outcomes are influenced by joint presence internal manufacturing branch. conduct two studies apparel industry show that function individual deployed relationship larger (concurrent singular)...

10.1002/smj.2145 article EN Strategic Management Journal 2013-05-13

Clinical and experimental studies show that spinal cord injury (SCI) can cause cognitive impairment depression significantly impact outcomes. Thus, identifying mechanisms responsible for these less well-examined, important SCI consequences may provide targets more effective therapeutic intervention. To determine whether depressive-like changes correlate with severity, we exposed mice to sham, mild, moderate, or severe using the Infinite Horizon Spinal Cord Impactor evaluated performance on a...

10.1089/neu.2015.4348 article EN Journal of Neurotrauma 2016-04-06

The emergence of the metaverse, a virtual reality space, has ushered in new era digital experiences and interactions global information systems. With its unique social norms behaviors, this world presents exciting opportunities for users to connect, socialize, explore. However, as people spend more time it become increasingly apparent that issue cyberbullying needs be addressed. Cyberbullying is serious problem can harm victims psychologically physically. It involves using technology harass,...

10.4018/jgim.325793 article EN Journal of Global Information Management 2023-07-10

NADPH oxidase (NOX2) is an enzyme system that generates reactive oxygen species (ROS) in microglia and macrophages. Excessive ROS production linked with neuroinflammation chronic neurodegeneration following traumatic brain injury (TBI). Redox signaling regulates macrophage/microglial phenotypic responses (pro-inflammatory versus anti-inflammatory), NOX2 inhibition moderate-to-severe TBI markedly reduces pro-inflammatory activation of macrophages/microglia resulting concomitant increases...

10.1186/s12974-017-0843-4 article EN cc-by Journal of Neuroinflammation 2017-03-24

Up until now, poor menstrual hygiene in developing countries has been an insufficiently acknowledged problem. The lack of attention to this issue is striking as we cannot achieve several Millennium Development Goals (MDGs), that is, 2, 3 4,5, and 5B. This study aimed assess the level awareness about menarche hygienic practices during menstruation context schooling.Community-based cross-sectional using a mix method approach (qualitative quantitative). It was conducted among 650 adolescent...

10.4103/0970-0218.170964 article EN cc-by-nc-sa Indian Journal of Community Medicine 2015-12-03

In business-to-business (B2B) markets, the success of key account management (KAM) teams depends on how they are structured and handle customer relationships. The authors conceptualize relationships among selling team members as a within-seller (intrafirm) network between buyer representatives buyer–seller (interfirm) network. Drawing both structural (buyer–seller density, centralization) functional similar function ties cross-functional ties) composition attributes these networks, examine...

10.1177/0022242918812056 article EN Journal of Marketing 2018-11-20

This article examines how a manufacturer's governance of an external supplier relationship affects its performance toward downstream retail customer. In line with sociological and economic theory, reliance on norms incentives, respectively, promotes performance. However, the effect each mechanism weakens in presence different regime within manufacturer firm itself. Specifically, internal incentives weaken norms, incentives. From practical standpoint, these findings point to difficulty...

10.1509/jmkg.75.2.1 article EN Journal of Marketing 2011-03-01
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