- Cancer-related gene regulation
- RNA Interference and Gene Delivery
- Carbohydrate Chemistry and Synthesis
- Epigenetics and DNA Methylation
- Substance Abuse Treatment and Outcomes
- HIV, Drug Use, Sexual Risk
- Cytokine Signaling Pathways and Interactions
- Child and Adolescent Psychosocial and Emotional Development
- Pesticide Exposure and Toxicity
- Radical Photochemical Reactions
- Alcohol Consumption and Health Effects
- Opioid Use Disorder Treatment
- Stress Responses and Cortisol
- Functional Brain Connectivity Studies
- Nuclear Receptors and Signaling
- Drug-Induced Hepatotoxicity and Protection
- Retinoids in leukemia and cellular processes
- Mental Health Treatment and Access
- Histone Deacetylase Inhibitors Research
- Health, Environment, Cognitive Aging
- SARS-CoV-2 and COVID-19 Research
- Infectious Encephalopathies and Encephalitis
- Genetics and Neurodevelopmental Disorders
- Migration, Health and Trauma
- Health disparities and outcomes
Indian Council of Medical Research
2013-2024
University of Miami
2023-2024
Institute of Mental Health
2022-2024
Midnapore Medical College and Hospital
2015-2022
National Institute of Occupational Health
2013-2021
Brown University
2021
National Institute for Implementation Research on Non-Communicable Diseases
2021
Government of India
2017
Ministry of Health and Family Welfare
2017
Sikkim Manipal University
2006-2015
BackgroundEarlier serosurveys in India revealed seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) 0.73% May–June 2020 and 7.1% August–September 2020. A third serosurvey was conducted between December January 2021 to estimate the SARS-CoV-2 infection among general population healthcare workers (HCWs) India.MethodsThe same 70 districts as first second serosurveys. For each district, at least 400 individuals aged ≥10 years from 100 HCWs subdistrict-level health...
Outbreaks of unexplained illness frequently remain under-investigated. In India, outbreaks an acute neurological with high mortality among children occur annually in Muzaffarpur, the country's largest litchi cultivation region. 2014, we aimed to investigate cause and risk factors for this illness.In hospital-based surveillance nested age-matched case-control study, did laboratory investigations assess potential infectious non-infectious causes illness. Cases were aged 15 years or younger who...
Arsenic, a contaminant of groundwater and irrigated crops, is global public health hazard. Exposure to low levels arsenic through food extends well beyond the areas with high content in water.
The anxiogenic action of caffeine (10, 25 and 50 mg/kg, i.p.) was investigated in rats compared with that yohimbine (2 i.p.). experimental methods used were the open-field, elevated plus-maze, social interaction novelty-suppressed feeding latency tests. Caffeine produced a dose-related profile behavioural changes, which qualitatively similar to those induced by indicate an activity rodents. Thus, both drugs reduced ambulation rears, increased immobility defaecation open-field test. They...
The behavioral activity profile of a therapeutically used alcoholic hypericum extract containing hyperforin (4.5 %) in rodent models was compared with that an experimental CO2 devoid hypericines but highly enriched (38.8 %). antidepressant activities 50, 150 and 300mg/ kg/day the were similar to those 5, 15 30 mg/kg/day respectively extract. ethanol same dose range potentiated dopaminergic responses, whereas these effects either absent or less pronounced treated groups. By contrast,...
Abstract Background Low and middle-income countries like India with a large youth population experience different environment from that of high-income countries. The Consortium on Vulnerability to Externalizing Disorders Addictions (cVEDA), based in India, aims examine environmental influences genomic variations, neurodevelopmental trajectories vulnerability psychopathology, focus externalizing disorders. Methods cVEDA is longitudinal cohort study, planned missingness design for yearly...
Background & objectives Cancer is one of the leading causes death among older adults worldwide. The global burden cancer individuals increasing due to ageing population. will pose significant social and economic challenges for delivery healthcare services. Materials Estimated new cases, deaths, age-standardized truncated incidence mortality rate per 100,000 (60 yr or above) were reported using GLOBOCAN 2020 estimates (gco.iarc.fr). Mortality Incidence ratio (M/I ratio) expressed in...
Standard therapies used for the treatment of acute myeloid leukemia (AML) are cytotoxic agents that target rapidly proliferating cells. Unfortunately, this therapeutic approach has limited efficacy and significant toxicity majority AML patients still die their disease. In contrast to poor prognosis most patients, individuals with a rare subtype AML, promyelocytic leukemia, can be cured by differentiation therapy using regimens containing all-trans retinoic acid. GSK3 been previously...
Background Chronic exposure to organophosphorus (OP) pesticides poses serious health risks. India, the largest pesticide producer in Asia, exposes its population residues through air, water, and food. Human biomonitoring is a crucial tool for estimating worldwide. OP compounds are potent cholinesterase inhibitors; acetylcholinesterase (AChE) inhibition can lead symptoms from weakness fatal respiratory or cardiac failure. Blood AChE assessment widely used as biomarker due exposure. Objectives...