A5074334713- Antimicrobial Resistance in Staphylococcus
- Virology and Viral Diseases
- SARS-CoV-2 and COVID-19 Research
- Animal Virus Infections Studies
- Bacterial Identification and Susceptibility Testing
- Animal Disease Management and Epidemiology
- Rabies epidemiology and control
- Mechanical Circulatory Support Devices
- Bacterial biofilms and quorum sensing
- Cardiac Structural Anomalies and Repair
- Viral Infections and Vectors
- Herpesvirus Infections and Treatments
- Transplantation: Methods and Outcomes
- Mycorrhizal Fungi and Plant Interactions
- COVID-19 epidemiological studies
- Streptococcal Infections and Treatments
- Nosocomial Infections in ICU
- Zoonotic diseases and public health
- Veterinary Oncology Research
- Microbial Metabolism and Applications
- Plant nutrient uptake and metabolism
- Sinusitis and nasal conditions
- Drug-Induced Adverse Reactions
- Cardiac Arrest and Resuscitation
- Cytomegalovirus and herpesvirus research
EcoHealth Alliance
2015-2022
Universiti of Malaysia Sabah
2022
Sabah Wildlife Department
2022
Columbia University
2005-2013
NewYork–Presbyterian Hospital
2005-2007
New York Hospital Queens
2005-2007
Presbyterian Hospital
2005
The death toll and economic loss resulting from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic are stark reminders that we vulnerable to zoonotic viral threats. Strategies needed identify characterize animal viruses pose greatest risk of spillover spread in humans inform public health interventions. Using expert opinion scientific evidence, identified host, viral, environmental factors contributing virus humans. We then developed a ranking framework interactive web...
Postinfluenza Staphylococcus aureus pneumonias are increasingly recognized as a major form of life-threatening infections.A mouse model postinfluenza S. pneumonia was developed. Mice were intranasally infected with bacteria alone or plus virus. Infection assessed by survival, lung histopathology, bacterial density in the lungs, and cellular response to infection.Mice both influenza virus showed higher mortality, greater parenchymal damage, at metastatic tissue sites than mice only aureus. At...
The legal and illegal trade in wildlife for food, medicine other products is a globally significant threat to biodiversity that also responsible the emergence of pathogens threaten human livestock health our global economy. Trade likely played role origin COVID-19, viruses closely related SARS-CoV-2 have been identified bats pangolins, both traded widely. To investigate possible pangolins as source potential zoonoses, we collected throat rectal swabs from 334 Sunda (Manis javanica)...
Staphylococcus epidermidis is the leading cause of device-related infections. These infections require an initial colonization step in which S. adheres to implanted material. This process usually mediated by specific bacterial surface proteins and host factors coating foreign device. Some these belong serine-aspartate repeat (Sdr) family, includes adhesins from Staphyloccus aureus epidermidis. Using a heterologous expression system Lactococcus lactis overcome possible staphylococcal...
Antibiotic-resistant Staphylococcus aureus infections have increased dramatically in the community, yet S. nasal colonization has remained stable. The objectives of this study were to determine if is a useful proxy measure disease transmission and infection community settings, identify potential reservoirs.Randomly selected households Northern Manhattan, completed structured social network questionnaire provided swabs that typed by pulsed field gel electrophoresis colonizing strains. main...
Methicillin-resistant Staphylococcus aureus is increasingly responsible for staphylococcal outbreaks in prison. There limited information on the source of outbreak strains, risk factors infection, and transmission these strains within a We conducted survey to determine prevalence nasal colonization with S. 2 New York State prisons. isolates from clinical cultures collected all prisons during 6-month period were compared colonizing strains. Analyses whether prison-level characteristics...
Abstract As part of a broad One Health surveillance effort to detect novel viruses in wildlife and people, we report several paramyxovirus sequences sampled primarily from bats during 2013 2014 Brazil Malaysia, including seven which recovered full-length genomes. Of these, six represent the first paramyxovirid genomes sequenced Americas, two that are bat morbillivirus genome published date. Our findings add vast number viral public repositories, have been increasing considerably recent years...
Macacine herpesvirus 1 (MaHV1; B virus) naturally infects macaques (Macaca spp.) and can cause fatal encephalitis in humans. In Peninsular Malaysia, wild are abundant, translocation is used to mitigate human-macaque conflict. Most adult infected with MaHV1, although the risk for transmission persons who handle them during capture unknown. We investigated MaHV1 shedding among 392 long-tailed (M. fascicularis) after by Department of Wildlife National Parks 2009-2011. For detection DNA, PCR was...
Abstract Objective: To evaluate the relationship between Staphylococcus aureus nasal and tracheal colonization infection in medical intensive care unit (MICU) patients. The primary outcome was incidence of S. colonized versus non-colonized Design: Prospective, observational cohort study. Patients admitted to MICU during study period were screened for by culture a PCR assay twice weekly. Demographic, clinical, microbiologic data collected 30 days after discharge. PFGE antibiotic...
Background: HIV-positive patients at HELP/PSI, Inc, an in-patient drug rehabilitation center, had a high baseline prevalence of Staphylococcus aureus colonization (49%) and incidence infection (17%) in previous year-long study. Methods: A randomized, double-blinded, placebo-controlled study was conducted to determine whether repeated nasal application mupirocin ointment would decrease the odds S. 100 HELP/PSI over 8-month period. 5-day course given monthly, assessed 1 month after each...
Abstract The legal and illegal trade in wildlife for food, medicine other products is a globally significant threat to biodiversity that also responsible the emergence of pathogens threaten human livestock health our global economy. Trade likely played role origin COVID-19, viruses closely related SARS-CoV-2 have been identified bats pangolins, both traded widely. To investigate possible pangolins as source potential zoonoses, we collected throat rectal swabs from 334 Sunda ( Manis javanica...
Interactions between roots and soil microbes are critical components of below-ground ecology. It is essential to quantify the magnitude root trait variation both among within species, including due plasticity. In addition contextualizing plasticity relative differences studies can ascertain if predictable whether an environmental factor elicits changes in traits that functionally advantageous. To compare functional plasticities fine tissues with natural reduced levels colonization by...
The Bornean sun bear (Helarctos malayanus euryspilus) is the smallest subspecies of bear. Their numbers are declining, and more research needed to better understand their health biology. Forty-four bears housed at Sun Bear Conservation Centre (BSBCC) in Sabah, Malaysia, were screened for known novel viruses November 2018. Ursid γ-herpesvirus type 1 (UrHV-1) a herpesvirus that has been detected from swab samples clinically healthy biopsy oral squamous cell carcinoma bears. We an...
Abstract As part of a broad One Health surveillance effort to detect novel viruses in wildlife and people, we report several paramyxoviruses sequenced primarily from bats during 2013 2014 Brazil Malaysia, including seven which recovered full-length genomes. Of these, six represent the first paramyxovirus genomes Americas, two sequences are bat morbillivirus published date. Our findings add vast number viral public repositories that have been increasing considerably recent years due rising...