A5025813651- Burkholderia infections and melioidosis
- Antibiotic Resistance in Bacteria
- Infections and bacterial resistance
- Genetic factors in colorectal cancer
- Colorectal Cancer Treatments and Studies
- Vibrio bacteria research studies
- Management of metastatic bone disease
- Galectins and Cancer Biology
- Cancer Genomics and Diagnostics
- Molecular Biology Techniques and Applications
- Glycosylation and Glycoproteins Research
- Paraquat toxicity studies and treatments
- Cancer Diagnosis and Treatment
- Escherichia coli research studies
- Lung Cancer Treatments and Mutations
Ho Chi Minh City Medicine and Pharmacy University
2021-2024
Vinmec International Hospital
2024
University Medical Center HCMC
2023
Mahidol University
2015
University of California, Davis
2007
We recently reported the use of matrix-assisted laser desorption ionization (MALDI) Fourier transformation mass spectrometry (FTMS) techniques to identify unique glycan markers in ovarian cancer cell lines which may be biomarkers for diagnosis cancer. Glycan and CA125 levels are compared a series patients normal control subjects. Oligosaccharides (OS) were cleaved from serum glycoproteins isolated using solid phase extraction. MALDI-FTMS was then used (MS) peaks. Sensitivity, specificity,...
To characterise the clinical features of Acinetobacter baumannii infections and investigate phylogenetic structure transmission dynamics A. in Vietnam. Between 2019 2020, a surveillance (AB) was conducted at tertiary hospital Ho Chi Minh City, Risk factors for in-hospital mortality were analysed using logistic regressions. Whole-genome sequence data used to genomic species, types (STs), antimicrobial resistance genes, surface antigens, relatedness AB isolates. Eighty-four patients with...
Identification of tumor-derived mutation (TDM) in liquid biopsies (LB), especially early-stage patients, faces several challenges, including low variant-allele frequencies, interference by white blood cell (WBC)-derived mutations (WDM), benign somatic and tumor heterogeneity. Here, we addressed the above-mentioned challenges a cohort 50 nonmetastatic colorectal cancer via workflow involving parallel sequencing paired WBC- tumor-gDNA. After excluding potential false positive mutations,...
Burkholderia pseudomallei is the causative agent of melioidosis. The complete genome sequences this pathogen have been revealed, which explain some pathogenic mechanisms. In various hostile conditions, for example, during nitrogen and amino acid starvation, bacteria can utilize alternative sigma factors such as RpoS RpoN to modulate genes expression their adaptation survival. study, we demonstrate that mutagenesis rpoN2 , lies on chromosome 2 B. encodes a homologue factor RpoN, did not alter...
Surgical site infection (SSIs) is a significant complication following bone cancer surgery, often resulting in reoperation, prolonged antibiotic use, and delays chemotherapy. It critical for patients with due to the invasiveness of immune suppression, chemotherapy regimens they undergo. In an effort reduce SSIs rate, our sarcoma teams implemented new intervention – pre-surgery screening methicillin-resistant Staphylococcus aureus (MRSA). A cross-sectional study was conducted, encompassing...
Background: Infections resulting from A. baumannii in hospitals lead to numerous severe consequences as its antibiotic resistance, particularly carbapenems, continues rise. Given that resistance characteristics undergo constant changes due mutations and gene transfer between species strains, monitoring the real-time circulation of resistant strains is essential. Methods: A descriptive cross-sectional method with analysis experimentation were applied this study. All isolated at University...