A5089991397- Electrospun Nanofibers in Biomedical Applications
- Advanced biosensing and bioanalysis techniques
- Wound Healing and Treatments
- Nanoparticle-Based Drug Delivery
- Nanocomposite Films for Food Packaging
- RNA Interference and Gene Delivery
- Nanoplatforms for cancer theranostics
- Tissue Engineering and Regenerative Medicine
- Nanopore and Nanochannel Transport Studies
- Conducting polymers and applications
- Dendrimers and Hyperbranched Polymers
- Hydrogels: synthesis, properties, applications
- Mesenchymal stem cell research
- Analytical Chemistry and Sensors
- Graphene and Nanomaterials Applications
- Antimicrobial agents and applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Microplastics and Plastic Pollution
- Photonic Crystals and Applications
- Electrostatics and Colloid Interactions
- Biosensors and Analytical Detection
- Mesoporous Materials and Catalysis
- Microfluidic and Capillary Electrophoresis Applications
- biodegradable polymer synthesis and properties
- DNA and Biological Computing
University of Science and Technology Beijing
2016-2025
Sichuan University
2024-2025
State Key Laboratory of Biotherapy
2024
Lanzhou University of Finance and Economics
2024
Communication University of China
2022
The application of the nanofiber film in field food preservation was an emerging research direction recent years. With functionalization nanofibers, quality and safety can be better guaranteed. In present work, thymol as antibacterial agent encapsulated into poly(lactide-co-glycolide) to form core–shell nanofibers by coaxial electrospinning. such a film, slowly released headspace between inhibiting growth bacteria on surface food. morphology structure were confirmed scanning electron...
DNA hydrogels have received considerable attention in analytical science, however, some limitations still exist the applications of intelligent hydrogels. In this paper, we describe a way to prepare gel film capillary tube based on thermal reversible principle hydrogel and action. Because slight change internal structure gel, its permeability can be increased by addition specific targets. The behavior is thus changed due different film. duration time target solution flowing through with...
Gene interference-based therapeutics represent a fascinating challenge and show enormous potential for cancer treatment, in which microRNA is used to correct abnormal gene. On the basis of above, we introduced microRNA-31 bind 3'-untranslated region mtEF4, resulting downregulation its messenger RNA protein trigger cells apoptosis through mitochondria-related pathway. To achieve better therapeutic effect, mesoporous silica nanoparticle-based controlled nanoplatform had been developed. This...
Diabetic wounds that do not heal for a long time challenge global healthcare. Mesenchymal stem cell (MSC) therapy has positive significance in promoting diabetic wound healing. However, traditional MSC involves exogenous MSCs, which brings many limitations and unsatisfactory treatment. Moreover, the maintenance of viability function is difficult because high level reactive oxygen species (ROS) wounds. Therefore, we developed nanofibrous dressing to recruit protect endogenous MSCs while...
Abstract To achieve an excellent delivery effect of drug, stimuli‐responsive nano “gate” with physical blockage units is usually constructed on the surface mesoporous silica nanocarriers (MSNs). In nature, aquaporins in cell membrane can control transport water molecules by regulating channel wettability, which resulted from conformational change amino acids channel. Inspired this phonomenon, herein a new concept free‐blockage controlled release system proposed, achieved controlling...
Multicellular spheroids can mimic the in vivo microenvironment and maintain unique functions of tissues, which has attracted great attention tissue engineering. However, traditional culture with structural deficiencies complicates collection process tends to lose function multicellular increase cell passage. In order construct efficient functional spheroids, this study, a chitosan/polyvinyl alcohol nanofiber sponge an open-cell cellular structure is obtained. The hair follicle (HF)...
A dual function system that inhibits tumor growth while promoting wound healing is very necessary for melanoma treatment since killing and skin are two complementary influential processes. Herein, a controllable local drug delivery based on porous fiber membranes incorporated with CuS nanoparticles designed chemo-photothermal synergistic therapy healing. The structure the surface significantly increases loading capacity of membrane photothermal effect used to control release rate....
World hunger is on the rise, yet one-third of food wasted. It necessary to develop an effective preservation method reduce waste. This article reports a composite film based chitosan biguanidine hydrochloride(CBg) and poly (N-vinyl-2-pyrrolidone)(PVP) that can be used as conformal coating for fresh produce. Due strong positive charge CBg, has excellent antibacterial properties. Owing hydrogen bonds between CBg PVP, good flexibility mechanical In addition, washable, transparent, evaporation...
Herein, voltage-responsive controlled release film was constructed by grafting ferrocene on the mesoporous inverse opal photonic crystal (mIOPC). The achieved free-blockage and realized monitoring of cargo without external indicator. Free-blockage attributed to voltage switchable nanovalves which undergo hydrophobic-to-hydrophilic transition when applying voltage. Monitoring optical property mIOPC, bandgap mIOPC had a red shift solution invaded in. hydrophobic enough stop intrusion. Once...
Abstract A pH‐controlled delivery system based on mesoporous silica nanoparticles (MSNs) was constructed for dual‐cargo selective release. To achieve a better controlled‐release effect, modified sol–gel method employed to obtain MSNs with tunable particle and pore sizes. The systems selectively released different kinds of cargo when stimulated by pH values. At the lower value (pH 2.0) only one kind from MSNs, whereas at higher 7.0) other MSNs. multi‐cargo has brought concept release new...