A5023365320- Autonomous Vehicle Technology and Safety
- Robotic Path Planning Algorithms
- Vehicle Dynamics and Control Systems
- Traffic control and management
- Control and Dynamics of Mobile Robots
- Advanced Neural Network Applications
- RNA modifications and cancer
- Influenza Virus Research Studies
- Reinforcement Learning in Robotics
- SARS-CoV-2 and COVID-19 Research
- Video Surveillance and Tracking Methods
- Cancer-related molecular mechanisms research
- Bioactive Compounds and Antitumor Agents
- Robotics and Sensor-Based Localization
- Computational Drug Discovery Methods
- melanin and skin pigmentation
- Vehicle emissions and performance
- Cancer, Hypoxia, and Metabolism
- Domain Adaptation and Few-Shot Learning
- COVID-19 and healthcare impacts
- Animal testing and alternatives
- Smart Parking Systems Research
- Genomics, phytochemicals, and oxidative stress
- interferon and immune responses
- Advanced Image and Video Retrieval Techniques
Institute of Laboratory Animal Science
2008-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2009-2024
Cixian People's Hospital
2024
Purdue University West Lafayette
2024
South China University of Technology
2021-2024
Beijing Friendship Hospital
2024
Capital Medical University
2024
Soochow University
2020-2023
JDSU (United States)
2019-2022
First Affiliated Hospital of Wannan Medical College
2021
In this manuscript, we introduce a real-time motion planning system based on the Baidu Apollo (open source) autonomous driving platform. The developed aims to address industrial level-4 problem while considering safety, comfort and scalability. covers multilane single-lane in hierarchical manner: (1) top layer of is strategy that handles lane-change scenarios by comparing lane-level trajectories computed parallel. (2) Inside trajectory generator, it iteratively solves path speed optimization...
This paper is focused on planning fast, accurate, and optimal trajectories for autonomous parking. Nominally, this task should be described as an control problem (OCP), wherein the collision-avoidance constraints guarantee travel safety kinematic tracking accuracy. The dimension of nominal OCP high because it requires vehicle to avoid collision with each obstacle at every moment throughout entire parking process. With a coarse trajectory guiding homotopic route, intractably scaled are...
Trajectory planning for a tractor-trailer vehicle is challenging due to the non-convex collision avoidance constraints and unstable kinematics. This article aims plan precise optimal trajectory car-like tractor that tows standard or general N-trailers in an environment with static obstacles. scheme can be formulated as unified control problem, but numerically solving problem difficult. Two efforts are made address difficulty. First, extended hybrid A* search algorithm proposed provide...
Pudilan (PDL), a four-herb prescription with the traditional function of heat-clearing and detoxifying, has been clinically used as an anti-SARS-CoV-2 infectory agent in China. PDL might also have therapeutic potentials for COVID-19 while underlying mechanisms remain to be clarified. We network pharmacology analysis selected 68 co-targeted genes/proteins targets both COVID-19. These were predicted by SwissDock Server their high-precision docking simulation, analyzed STRING proteins protein...
This letter is focused on the time-optimal Multi-Vehicle Trajectory Planning (MVTP) problem for multiple car-like robots when they travel in a tiny indoor scenario occupied by static obstacles. Herein, complexity of concerned MVTP task includes i) non-convexity and narrowness environment, ii) nonholonomy nonlinearity vehicle kinematics, iii) pursuit solution, iv) absence predefined homotopic routes vehicles. The aforementioned factors, mixed together, are beyond capability prevalent coupled...
Trajectory planning for a tractor-trailer vehicle is challenging because the kinematics consists of underactuated and nonholonomic constraints that are highly coupled. Prevalent sampling-based or search-based planners suitable rigid-body vehicles not capable handling cases. This work aims to deal with generic n-trailer cases in tiny environments. To this end, an optimal control problem formulated, which beneficial being accurate, straightforward, unified. An adaptively homotopic...
Germacrone, curdione, and furanodiene have been shown to be useful in the treatment of breast cancer but pharmacological mechanism action is unclear. In this paper, we explored a new method study molecular network function Traditional Chinese Medicine (TCM) herbs their corresponding ingredients with bioinformatics tools, including PubChem Compound Database, BATMAN-TCM, SystemsDock, Coremine Medical, Gene ontology, KEGG. Eleven targeted genes/proteins, 4 key pathways, 10 biological processes...
Abstract Background Breast cancer is the most common in women, and advanced stages, it often metastasizes to brain. However, research on biological mechanisms of breast brain metastasis potential therapeutic targets are limited. Methods Differential gene expression analysis (DEGs) for datasets GSE43837 GSE125989 from GEO database was performed using online tools such as GEO2R Sangerbox. Further investigation related SULF1 conducted databases Kaplan–Meier Plotter cBioPortal. Thus, levels,...
An optimal control problem is a straightforward description of generic automatic parking maneuver planning scheme. However, the dimensionality usually high, primarily because large-scale collision avoidance constraints. Among complete constraints, some parts are redundant ego vehicle may not be subject to collisions with all obstacles at every moment. idea simplify constraints plan coarse path/trajectory, and then construct surrounding corridor which naturally separates from obstacles. This...
Laboratory animal science (LAS) advances scientific understanding of the care and use animals that play a key role in research supporting development biomedicine. LAS has developed quickly China recent decades, this report provides an analysis current status countrys policies administration. National provincial laws, regulations, guidelines, standards apply to quality control licensing, quarantine infectious disease control, breeding husbandry, transgenic animals, staff qualifications,...
On-road trajectory planning is a critical module in an autonomous driving system. Instead of using path-velocity decomposition or longitudinal-lateral strategy, this work aims to find directly. We adopt sampleand-search planner get coarse and then polish it via numerical optimization. Among the predominant planners, most sampling operations are not flexible, which inevitably lead solution failure if density low, suffer from curse dimensionality set high. This proposes modified RRT* for...
This article introduces a technical solution for autonomous last-mile delivery in challenging traffic conditions. The methodologies each module of the company's vehicles are presented together with safety guarantee strategies.
Gastric cancer is one of the leading prevalent and malignant cancers worldwide, especially in east Asia.However, in-depth molecular mechanism underlying gastric progression remains uncertain.Recently, studies have identified that long non-coding RNA (lncRNA) could play critical roles tumorigenesis multiple types cancer.Studies on BLACAT2 proven it participates bladder colorectal regulation was as highly expressed using cBioPortal for Cancer Genomics cancer.However, precise function...
C1QL3 is widely expressed in the brain and specifically produced by a subset of excitatory neurons. However, its function still not clear. We established C1ql3-deficient rats to investigate role brain.
Abstract Experimental animals including the ferret, marmoset, woodchuck, mini pig, and tree shrew have been used in biomedical research. However, their gut microbiota not fully investigated. In this study, of these five experimental were analyzed with 16S rRNA sequencing. The phyla Firmicutes, Bacteroidetes, Fusobacteria present all species. Specific different animals: Proteobacteria Tenericutes Spirochaetes pig. Fusobacterium unidentified Clostridiales dominant genera whereas Libanicoccus ,...
Mouse has been extensively used as a tool for investigating the onset and development of human neurological disorders. As first step to construct transgenic mouse model brain lesions, it is fundamental importance clarify similarity divergence genetic background between non-diseased tissues.We systematically compared, based on large scale integrated microarray data, transcriptomes three anatomically distinct regions; prefrontal cortex (PFC), hippocampus (HIP) striatum (STR), across mouse. The...