A5075981087- Neuroendocrine regulation and behavior
- Autism Spectrum Disorder Research
- Attention Deficit Hyperactivity Disorder
- Diet and metabolism studies
- Birth, Development, and Health
- Genetics and Neurodevelopmental Disorders
- Neurotransmitter Receptor Influence on Behavior
- Neurobiology and Insect Physiology Research
- Prenatal Substance Exposure Effects
- Epigenetics and DNA Methylation
- Amphibian and Reptile Biology
- Receptor Mechanisms and Signaling
- Insect and Pesticide Research
- Animal Behavior and Reproduction
- Metabolism and Genetic Disorders
- Adipose Tissue and Metabolism
- Genetic Syndromes and Imprinting
- Gestational Diabetes Research and Management
- Gastrointestinal motility and disorders
- Protein purification and stability
- Law, logistics, and international trade
- Peroxisome Proliferator-Activated Receptors
- Trypanosoma species research and implications
- Crustacean biology and ecology
- Aquaculture disease management and microbiota
University of Zagreb
2011-2024
We tested the hypothesis that gestational diabetes mellitus (GDM) alters DNA methylation pattern of fetal serotonin transporter gene (SLC6A4), and examined functional relevance for regulation SLC6A4 expression in human placenta. The study included 50 mother-infant pairs. Eighteen mothers were diagnosed with GDM 32 had normal glucose tolerance (NGT). All neonates birth weight born at term by planned Cesarean section. RNA isolated from samples tissue collected side placenta immediately after...
Disturbed brain and peripheral serotonin homeostasis is often found in subjects with autism spectrum disorder (ASD). The role of the receptor 2A (HTR2A) regulation central homeostasis, as well its altered expression autistic subjects, have implicated HTR2A gene a major candidate for disturbance seen autism. Several studies, yielding so far inconclusive results, attempted to associate functional SNP -1438 G/A (rs6311) promoter region, while possible contribution epigenetic mechanisms, such...
Serotonin (5-hydroxytryptamine, 5HT) homeostasis is essential for many physiological processes in the central nervous system and peripheral tissues. Hyperserotonemia, a measurable sign of 5HT disruption, can be caused by 5HT-directed treatment psychiatric gastrointestinal diseases. Its impact on long-term balance function compartment remains unresolved requires further research due to possible effects human health. We explored perinatal imbalance organs responsible serotonin metabolism—the...
Temperature is the most important abiotic factor and has a direct influence on physiology of organism, affecting nearly all other parameters living environment organisms. Ectothermic organisms are highly endangered in current crisis climate, as they unable to use metabolic heat maintain body temperature. Reptiles ectothermic vertebrates that also susceptible temperature fluctuations. Metabolism, muscle nervous system function reproduction closely linked reptile To study effects oxidative...
Immunity is an important component of invasion success since it enables invaders’ adaptation to conditions the novel environment as they expand their range. Immune response invaders may vary along range due encountered parasites/microbial communities, local environment, and ecological processes that arise during expansion. Here, we analyzed changes in immune one most successful aquatic invaders, signal crayfish, recently invaded Korana River, Croatia. We used several standard parameters...
Abstract Serotonin (5HT) is a biologically active amine with diverse roles in the mammalian organism. Developmental alterations 5HT homeostasis could lead to exposure of developing brain non-optimal serotonin concentrations that may result developmental and behavioral deficits. In order explore molecular basis effects disturbances on metabolism adult central homeostasis, observed our previous studies, we measured changes gene expression neuronal 5HT-regulating proteins animals after...
There are few studies on oxidative stress in reptiles and there is a lack of basic knowledge the tissues widely distributed Italian wall lizard (Podarcis siculus). The aim present preliminary study was to test compare biological antioxidant potential (BAP), total superoxide dismutase (SOD) glutathione peroxidase (GSH-Px) derivatives reactive oxygen metabolites (d-ROM) muscle tissue between two populations P. siculus. Two free-living groups eight adult males were included each group (N=16)....
Abstract Serotonin (5-hydroxytryptamine, 5HT) regulates the development of 5HT neurons and target tissues during neurogenesis, while later it assumes function a neurotransmitter. Alterations in serotonin neurotransmission are indicated as biological substrates several neuropsychiatric disorders, including autism. The most consistent 5HT-related finding autistic disorder is hyperserotonemia, but mechanism its relation to central dysfunction still unclear. In an attempt pharmacologically...