A5029141324- Protist diversity and phylogeny
- Genetic and Kidney Cyst Diseases
- Renal and related cancers
- Photoreceptor and optogenetics research
- Cerebrospinal fluid and hydrocephalus
- Structural mechanics and materials
- Microtubule and mitosis dynamics
- Galectins and Cancer Biology
- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Genetic Neurodegenerative Diseases
- Orbital Angular Momentum in Optics
- Immune Cell Function and Interaction
- Microbial Community Ecology and Physiology
- Microfluidic and Capillary Electrophoresis Applications
- Nuclear Structure and Function
- Micro and Nano Robotics
- Photosynthetic Processes and Mechanisms
- Geodetic Measurements and Engineering Structures
- RNA Research and Splicing
- Spinal Dysraphism and Malformations
- Epigenetics and DNA Methylation
- Neonatal Respiratory Health Research
- Advanced Energy Technologies and Civil Engineering Innovations
- Fetal and Pediatric Neurological Disorders
University of Fukui
2025
University of Yamanashi
2020-2022
University of Tsukuba
2013-2021
University of Toyama
2011-2013
Abstract The dynamics of cerebrospinal fluid (CSF) are essential for maintaining homeostasis in the central nervous system. Despite insufficiently detailed descriptions their structural and molecular properties a century, cranial arachnoid granulations (CAGs) on meninges have been thought to participate draining CSF from subarachnoid space into dural sinuses. However, recent studies demonstrated existence other types drainage systems, such as lymphatic vessels adjacent sinus paravascular...
ABSTRACT The individual role of the outer dynein arm light chains in molecular mechanisms ciliary movements response to second messengers, such as Ca 2+ and cyclic nucleotides, is unclear. We examined gene termed chain 1 (LC1) Paramecium tetraurelia ( ODAL1 ), a homologue LC1 Chlamydomonas reinhardtii , by RNA interference (RNAi) using feeding method. -silenced -RNAi) cells swam slowly, their swimming velocity did not increase membrane-hyperpolarizing stimuli. Ciliary on cortical sheets...
Light-responsive regulation of ciliary motility is known to be conducted through modulation dyneins, but the mechanism not fully understood. Here, we report a novel subunit two-headed f/I1 inner arm dynein, named DYBLUP, in animal spermatozoa and unicellular green alga. This contains BLUF (sensors blue light using FAD) domain that appears directly modulate dynein activity response light. DYBLUP (dynein-associated protein) mediates connection between motor tether complex links doublet...
Abstract The phosphoarginine shuttle system effectively regenerates ATP in the cilia of Paramecium caudatum . To estimate effective concentration ATP‐regenerating enzymes, we attempted to reconstitute certain systems within intact cortical sheets using exogenous enzymes and high‐energy substances. addition phosphoenolpyruvate, which is one substrates glycolysis, did not increase ciliary beat frequency, whereas phosphocreatine together with creatine kinase, increased frequency. In presence...
Abstract Primary cilia are ubiquitous hair-like organelles, usually projecting from the apical cell surface. They essential for organogenesis and homeostasis of various physiological functions, their dysfunction leads to a plethora human diseases. However, there few reports on role primary in immune system; therefore, we focused thymus that nurtures immature lymphocytes full-fledged T cells. After detecting thymic epithelial (TEC) expressed transforming growth factor β (TGF-β) receptor basal...