A5028775117- Protist diversity and phylogeny
- Microbial Community Ecology and Physiology
- Paleontology and Stratigraphy of Fossils
- Marine Biology and Ecology Research
- Genomics and Phylogenetic Studies
- Diatoms and Algae Research
- Biocrusts and Microbial Ecology
- Microtubule and mitosis dynamics
- Marine and coastal ecosystems
- Synthetic Organic Chemistry Methods
- Photosynthetic Processes and Mechanisms
- Cancer, Hypoxia, and Metabolism
- Algal biology and biofuel production
- Nerve injury and regeneration
- Legionella and Acanthamoeba research
- Cancer, Lipids, and Metabolism
- Insect symbiosis and bacterial influences
- Curcumin's Biomedical Applications
- Developmental Biology and Gene Regulation
- Calpain Protease Function and Regulation
- Magnetic Properties and Synthesis of Ferrites
- Organoselenium and organotellurium chemistry
- Metabolomics and Mass Spectrometry Studies
- Health and Wellbeing Research
- Genetic and Kidney Cyst Diseases
Yamagata University Hospital
2025
Yamagata University
2023-2024
University of Tsukuba
2010-2021
Kyoto University
2019
Chubu University
2018
National Institute of Mental Health
2017
National Center of Neurology and Psychiatry
2017
Kitakyushu National College of Technology
2014
The University of Tokyo
2007-2011
Hokkaido University
2000-2011
The division of life into producers and consumers is blurred by evolution. For example, eukaryotic phototrophs can lose the capacity to photosynthesize, although they may retain vestigial plastids that perform other essential cellular functions. Chrysophyte algae have undergone a particularly large number photosynthesis losses. Here, we present plastid genome sequence from nonphotosynthetic chrysophyte, "Spumella" sp. NIES-1846, show it has retained nearly identical set plastid-encoded...
Rapidly accumulating genetic data from environmental sequencing approaches have revealed an extraordinary level of unsuspected diversity within marine phytoplankton,1de Vargas C. Audic S. Henry N. Decelle J. Mahé F. Logares R. Lara E. Berney Le Bescot Probert I. et al.Tara Oceans CoordinatorsOcean plankton. Eukaryotic plankton in the sunlit ocean.Science. 2015; 348: 1261605Crossref PubMed Scopus (955) Google Scholar, 2Massana del Campo Sieracki M.E. Exploring uncultured microeukaryote...
Bacteria with endosymbiotic lifestyles often exhibit dramatic genome reduction. While the reduction of genomes in intracellular symbionts animals, including parasitic bacteria, has been extensively studied, less is known about such bacteria associated single-celled eukaryotes. Here, we report two novel gammaproteobacterial lineages, RS3 and XS4, identified as putative endosymbionts dinoflagellate Citharistes regius. Phylogenetic analyses suggest that XS4 belong to family...
Abstract This study was performed to assess interrater reliability of the Japanese version Physical Self-Maintenance Scale (PSMS) and Instrumental Activities Daily Living (IADL), which are simple efficient assessment instruments functional abilities in elderly patients. The subjects were 25 consecutive patients with Alzheimer's disease who outpatients Department Neuropsychiatry Ehime University School Medicine their principal caregivers. One neuropsychiatrist administered PSMS IADL, all...
Abstract Calaxin is a Ca 2+ -binding dynein-associated protein that regulates flagellar and ciliary movement. In ascidians, calaxin plays essential roles in chemotaxis of sperm. However, nothing has been known for the function vertebrates. Here we show mice with null mutation Efcab1 , which encodes calaxin, display typical phenotypes primary dyskinesia, including hydrocephalus, situs inversus abnormal motility trachea cilia sperm flagella. Strikingly, both males females are viable fertile,...
Scope The induction of brown‐like adipocytes in white adipose tissue (WAT) is a potential therapeutic target for the treatment obesity and metabolic disorders via ability these cells to release excess energy as heat association with uncoupling protein 1. Some experimental trials suggest that curcumin (a yellow pigment from turmeric) has suppressive effect on accumulation body fat. However, there little evidence show induces formation molecular mechanisms involved remain elusive. In addition,...
Cyanobacteria are one of the most important contributors to oceanic primary production and survive in a wide range marine habitats. Much effort has been made understand their ecological features, diversity, evolution, based mainly on data from free-living cyanobacterial species. In addition, symbiosis emerged as an lifestyle microbes increasing knowledge cyanobacteria symbiotic relationships with unicellular eukaryotes suggests significance understanding global ecosystem. However, detailed...
The diversity of marine cyanobacteria has been extensively studied due to their vital roles in ocean primary production. However, little is understood about the cyanobacterial species involved symbiotic relationships. In this study, we successfully sequenced complete genome a cyanobacterium symbiosis with Citharistes regius, dinoflagellate thriving open ocean. A phylogenomic analysis revealed that (CregCyn) belongs picocyanobacterial lineage, akin another symbiont (OmCyn) different closely...
The Ciona intestinalis protein database (CIPRO) is an integrated for the tunicate species C. . unique in two respects: first, because of its phylogenetic position, suitable model understanding vertebrate evolution; and second, includes original large-scale transcriptomic proteomic data. has also been a favorite developmental biologists. Therefore, large amounts data exist on development morphology, along with recent genome sequence gene expression CIPRO aimed at collecting those published as...
Most euglyphids, a group of testate amoebae, have shell that is constructed from numerous siliceous scales. The euglyphid Paulinella chromatophora has photosynthetic organelles (termed cyanelles or chromatophores), allowing it to be cultivated more easily than other euglyphids. Like P. made brick-like These scales are varied in size and shape. How cell makes this still mystery. We examined construction process detail using time-lapse video microscopy. new was by specialized pseudopodium laid...
Light-responsive regulation of ciliary motility is known to be conducted through modulation dyneins, but the mechanism not fully understood. Here, we report a novel subunit two-headed f/I1 inner arm dynein, named DYBLUP, in animal spermatozoa and unicellular green alga. This contains BLUF (sensors blue light using FAD) domain that appears directly modulate dynein activity response light. DYBLUP (dynein-associated protein) mediates connection between motor tether complex links doublet...
Ti-doped and undoped CaFe2O4 powders were prepared from a malic acid complex their properties evaluated using analytical instruments. According to an XRD measurement, there no traces of impurity phases in 5 mol % powder, while such as α-Fe2O3 CaTiO3 observed for 10 CaFe2O4. When Ti was added CaFe2O4, the crystallite growth suppressed BET surface area increased. SEM observation revealed that addition atoms causes interconnected particles separate. From results XRF it is suggested Fe are...
Abstract Chloroplasts in photosynthetic eukaryotes originated from a cyanobacterial endosymbiosis far more than 1 billion years ago 1-3 . Due to this ancientness, it remains unclear how evolutionary process proceeded. To unveil mystery, we analysed the whole genome sequence of rhizarian amoeba 4 , Paulinella micropora 5,6 which has chloroplast-like organelle that another 7-10 about 0.1 11 Here show predacious engulfed cyanobacteria evolved into organism very quickly time scale, probably...
A haptonema is an elongated microtubule-based motile organelle uniquely present in haptophytes. The most notable and rapid movement of a “coiling”, which occurs within few milliseconds following mechanical stimulation unknown motor-independent mechanism. Here, we analyzed the coiling process detail by high-speed filming showed that was initiated left-handed twisting haptonema, followed writhing to form helix from distal tip. On recovery stimulus, slowly uncoiled proximal region. Electron...
Extant eukaryote ecology is primarily sustained by oxygenic photosynthesis, in which chlorophylls play essential roles. The exceptional photosensitivity of allows them to harvest solar energy for but on the other hand, they also generate cytotoxic reactive oxygen species. A risk such phototoxicity chlorophyll must become particularly prominent upon dynamic cellular interactions that potentially disrupt mechanisms are designed quench photoexcited phototrophic cells. Extensive examination a...
Intracellular transport of neurotrophin receptors together with neurotrophins is one the key events signaling for growth and survival neurons. However, involvement in regulation intracellular has been remained unclear. We visualized behavior TrkA, a receptor nerve factor (NGF), by labeling GFP PC12 cells. found remarkable changes TrkA-GFP upon application NGF. Before application, only ~37% fluorescent dots TrkA showed translocations along neurites After number showing directional movement...
Paulinella micropora is a rhizarian thecate amoeba, belonging to photosynthetic species group that has unique organelle termed chromatophore, whose cyanobacterial origin distinct from of plant and algal chloroplasts. Because acquisition the chromatophore was quite recent event compared with chloroplast ancestor, are thought be model organisms for studying early process primary endosymbiosis. To obtain insight into how endosymbiotically transferred genes acquire expression competence in host...
Placenta accreta carries an increased risk of maternal morbidity and mortality (1), but prenatal diagnosis may be difficult. We describe here a case placenta without previa diagnosed before delivery succeeded in preservation the uterus by uterine artery embolization (UAE). A 34-year-old woman was referred to our hospital at 26 weeks gestation because intrauterine growth restriction (IUGR) with placental abnormality. She had one previous normal term spontaneous abortion. On gray scale...
The diversity of marine cyanobacteria has been extensively studied due to their vital roles in ocean primary production. However, little is understood about the cyanobacterial species involved symbiotic relationships. In this study, we successfully sequenced complete genome a cyanobacterium symbiosis with Citharistes regius , dinoflagellate thriving open ocean. A phylogenomic analysis revealed that (CregCyn) belongs picocyanobacterial lineage, akin another symbiont (OmCyn) different closely...
Flagellar movement and mating behavior of the biflagellate gametes marine green macroalga, Chaetomorpha spiralis were studied using high-speed video microscopy field emission scanning electron (FE-SEM) to clarify role flagella during rapid fertilization macroalgae. Discharged isogametes always swung their backward forward swimming. The beat pattern was flagellar with undulatory waves produced at base being propagated toward tip. One cycle took 15 ms. When suspension mixed that opposite...