A5080384211- Enzyme Production and Characterization
- Biofuel production and bioconversion
- Polysaccharides and Plant Cell Walls
- Studies on Chitinases and Chitosanases
- Photosynthetic Processes and Mechanisms
- Polysaccharides Composition and Applications
- Enzyme Catalysis and Immobilization
- Algal biology and biofuel production
- Microbial Metabolic Engineering and Bioproduction
- Protist diversity and phylogeny
- Microbial Metabolites in Food Biotechnology
- Fungal Biology and Applications
- Monoclonal and Polyclonal Antibodies Research
- Phytase and its Applications
- Plant Virus Research Studies
- Microbial Community Ecology and Physiology
- Insect Resistance and Genetics
- Glycosylation and Glycoproteins Research
- Photoreceptor and optogenetics research
- Transgenic Plants and Applications
- Viral Infectious Diseases and Gene Expression in Insects
- Enzyme Structure and Function
- Microbial metabolism and enzyme function
- Web Data Mining and Analysis
- Metabolism and Genetic Disorders
Osaka Metropolitan University
2022-2024
Tokyo Metropolitan University
2023-2024
Osaka Prefecture University
2013-2023
Shionogi (Japan)
2020-2022
Japan Science and Technology Agency
2015-2018
ENVIRON (United States)
2017
KDDI Research (Japan)
2012
Tokyo Gakugei University
2005
Osaka University
2004
Showa University
1998
Abstract Euglena gracilis produces wax ester under hypoxic and anaerobic culture conditions with a net synthesis of ATP. In fermentation, fatty acids are synthesized by reversing beta‐oxidation in mitochondria. A major species produced E. is myristyl myristate (14:0‐14:0Alc). Because its shorter carbon chain length saturated compounds, biodiesel from may have good cold flow properties high oxidative stability. We reasoned that slight metabolic modification would enable to produce biofuel...
ABSTRACT Euglenoids (Euglenida) are unicellular flagellates possessing exceptionally wide geographical and ecological distribution. combine a biotechnological potential with unique position in the eukaryotic tree of life. In large part these microbes owe this success to diverse genetics including secondary endosymbiosis likely additional sources genes. Multiple euglenoid species have translational applications show great promise production biofuels, nutraceuticals, bioremediation, cancer...
Microalgal oil production represents a promising renewable biofuel source. Metabolic engineering can enhance its utility, transforming it into an improved and expanding applications as feedstock for commodity chemicals, thereby increasing their value in biorefineries. This study focused on anaerobic wax ester by the microalga Euglena gracilis, aiming to develop stable mutant strains with altered profiles through genome editing. Two enzymes fatty acid beta-oxidation pathway involved were...
Baloxavir marboxil is an oral anti-influenza drug that inhibits the cap-dependent endonuclease of virus polymerase acidic protein. In clinical trials, baloxavir reduced time to alleviation influenza symptoms and resolution fever in adults, adolescents, children. The purpose this study collect data on safety effectiveness when used practice. This postmarketing surveillance (clinicaltrials.jp; JapicCTI-183882), conducted at 688 Japanese hospitals or clinics (March 2018 March 2019), enrolled...
The saccharification process is essential for bioethanol production from woody biomass including celluloses. Cold-adapted cellulase, which has sufficient activity at low temperature (<293 K), capable of reducing heating costs during the and suitable simultaneous fermentation. Endo-1,4-β-glucanase earthworm Eisenia fetida (EF-EG2) belonging to glycoside hydrolase family 9 been shown have highest 313 K, also retained a comparatively high 283 K. recombinant EF-EG2 was purified expressed in...
This prospective post-marketing surveillance (PMS) was designed to collect data on the safety and effectiveness of naldemedine in routine clinical practice patients with opioid-induced constipation (OIC) cancer pain Japan explore characteristics prone diarrhea.The enrolled received (0.2 mg, once a day) orally for up 12 weeks. In analysis, adverse drug reactions (ADRs), including diarrhea as special interest, were assessed. Effectiveness evaluated, especially regarding frequency condition...