A5018134531- Diet, Metabolism, and Disease
- Adipokines, Inflammation, and Metabolic Diseases
- Adipose Tissue and Metabolism
- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Fatty Acid Research and Health
- Cardiovascular Disease and Adiposity
- Nutrition and Health in Aging
- Biochemical effects in animals
- Healthcare Regulation
- Agricultural and Food Sciences
- Antioxidant Activity and Oxidative Stress
- Nutritional Studies and Diet
- Regulation of Appetite and Obesity
- Advanced Glycation End Products research
- Youth, Drugs, and Violence
- Pharmacology and Obesity Treatment
- Phytochemistry Medicinal Plant Applications
- Physical Education and Gymnastics
- Eating Disorders and Behaviors
- Dye analysis and toxicity
- Folate and B Vitamins Research
- Birth, Development, and Health
- Health and Lifestyle Studies
- Coffee research and impacts
Universidade Estadual Paulista (Unesp)
2013-2024
Faculdades Integradas de São Paulo
2023
ORCID
2021
Medecell (Brazil)
2015
The high consumption of fat and sugar contributes to the development obesity co-morbidities, such as diabetes, cardiovascular kidney diseases. Different strategies have been used prevent these diseases associated with obesity, changes in eating habits and/or addition dietary components anti-inflammatory anti-oxidant properties, gamma-oryzanol (γOz) present mainly bran layers rice germ.Animals were randomly divided into four experimental groups fed ad libitum for 20 weeks control diet (C, n =...
Background: The higher consumption of fat and sugar are associated with obesity development its related diseases such as non-alcoholic fatty liver disease (NAFLD). Lycopene is an antioxidant whose protective potential on degeneration has been investigated. aim this study was to present the therapeutic effects lycopene NAFLD induced by a hypercaloric diet. Methods: Wistar rats were distributed in two groups: Control (Co, n = 12) (Ob, 12). After 20 weeks, animals redistributed into control...
Obesity is considered an important risk factor for several disorders, such as diabetes mellitus, systemic arterial hypertension, dyslipidemia, and atherosclerosis, which are associated with inflammation oxidative stress a trigger factor. Passiflora edulis contains bioactive compounds, phenolics, carotenoids, vitamin C, polyamines in pulp, leaves, seeds, bark. Aim: To evaluate the effect of bark (BPe) on body composition, metabolic parameters genetically obese mice. Methods: Obese male db/db...
A atrofia muscular espinhal (AME) é uma desordem neuromuscular genética rara, subdividida em 5 tipos, com diferentes formas de manifestação, sintomas e intensidade da doença. Do ponto vista nutricional, crianças AME são mais suscetíveis a alterações do estado como desnutrição obesidade, risco significativo morbidade para ambas. Ainda, evidências crescentes sugerem anormalidades metabólicas pacientes AME, metabolismo ácidos graxos alterado tolerância à glicose prejudicada. Assim, o...
Oxidative stress is involved in pathophysiological mechanisms associated with a myriad of liver diseases. Bergamot (Citrus bergamia) leaves yield high level antioxidant polyphenolic compounds that may hinder the development diseases, while their potential yet to be fully explored. Thus, aim study was test effects bergamot leaf extract (BLE) on hepatic and mitochondrial oxidative different models. In vivo study: Wistar rats were distributed into two groups: control diet (C) high-sugar–fat...
The effects of hydroethanolic extract Yacon leaves (HEYL) on antioxidant, glycemic, and inflammatory biomarkers were tested in diabetic rats. Outcome parameters included glucose, insulin, interleukin-6 (IL-6), hydrophilic antioxidant capacity (HAC) serum IL-6, HAC, malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) soleus. rats (10/group) divided as follows: C, controls; C + Y, HEYL treated; DM, DM treated with HEYL. Diabetes mellitus was induced...
Abstract Obesity is associated with low-grade inflammation, triggered in adipose tissue, which may occur due to an excess of SFA from the diet that can be recognised by Toll-like receptor-4. This condition involved development components metabolic syndrome obesity, especially insulin resistance. The aim study was evaluate manifestation and tissue inflammation as a function period time rats were submitted high-sugar/fat (HSF). Male Wistar divided into six groups receive control (C) or HSF for...
The kidney is an important organ in the maintenance of body homeostasis. Dietary compounds, reactive metabolites, obesity, and metabolic syndrome (MetS) can affect renal filtration whole homeostasis, increasing risk chronic disease (CKD) development. Gamma oryzanol ( γ Oz) a compound with antioxidant anti‐inflammatory activity that has shown positive action treatment obesity diseases. Aim . To evaluate effect Oz to recover function obese animals by high sugar‐fat diet modulation adiponectin...
Bergamot (Citrus bergamia) is a fruit with anti-inflammatory and antioxidant properties that contains similar bioactive composition to its leaf, evidencing therapeutic potential in the treatment of chronic diseases. The aim was evaluate effect bergamot leaf extract (BLE) on redox/inflammatory scenario different organs obese rats metabolic syndrome. After detection syndrome, male Wistar were allocated (n = 10/group) for BLE by gavage (50 mg/kg): Control, Control+BLE, High Sugar fat (HSF),...
The excessive consumption of diets rich in sugar and fat is associated with metabolic manifestations involving adipose tissue the liver. Bergamot, due to its antioxidant anti-inflammatory properties, has been used treat disorders. This work aimed verify effect Bergamot leaves extract (BLE) on crosstalk tissue–liver axis obese rats. For 20 weeks, Wistar rats were distributed into two groups: control (Control) high sugar–fat (HSF) diet groups. Afterwards, animals redistributed three groups for...
The high consumption of fat and sugar contributes to the development obesity co-morbidities, such as dyslipidemia, hypertension, cardiovascular disease. aim this study was evaluate association between dyslipidemia cardiac dysfunction induced by western diet consumption. Wistar rats were randomly divided into two experimental groups fed ad libitum for 20 weeks with a control (Control, n = 12) or high-sugar high-fat (HSF, 12). HSF group also received water + sucrose (25%). Evaluations included...
The system redox imbalance is one of the pathways related to obesity-related cardiac dysfunction. Lycopene considered best antioxidants. aim this study was test if tomato-oleoresin would be able recovery function by improving β-adrenergic response due its antioxidant effect. A total 40 animals were randomly divided into two experimental groups receive either control diet (Control, n = 20) or a high sugar-fat (HSF, for 20 weeks. Once dysfunction detected echocardiogram in HSF group, re- begin...
Abstract Purpose This study aimed to evaluate the effect of rice bran (RB) supplementation a high-sugar fat (HSF) diet on cardiac dysfunction in an experimental obesity model. Methods Male Wistar rats were distributed into three groups: control, fat, and supplemented with 11% RB for 20 weeks. Results HSF promoted metabolic complications. Obese showed structural functional impairment associated high levels interleukin-6, tumoral necrosis factor alpha, malondialdehyde, decreased activity...
Resumo Introdução: A obesidade é uma doença em que a inflamação está inteiramente envolvida e pode causar insuficiência renal. Objetivo: Avaliar influência da exposição curto prazo de dieta cafeteria sobre no tecido renal formação produtos glicação avançada (AGEs) plasma rato. Métodos: Ratos Wistar machos (10 semanas idade, pesando 350 g) foram designados para receber ração comercial (C; n = 8 animais/grupo, 5% energia partir gordura) ou (CAF-D, animais/grupo: 29% sacarose água (300 g/L)...
To investigate the effects of fructose consumption on antioxidant capacity in heart and kidney, cardiovascular disease risk factors, evaluation these variables after its removal.Male Wistar rats (n = 36) were divided into control group 12): standard chow + water or F group: drinking (30%) for 15 weeks. After, was to continue receiving 12) (Ex group, n 9 Water, caloric diaries intake, final body weight, adiposity index, plasma glucose triacylglycerol, systolic blood pressure, cardiac renal...