A5074453978- Cardiac Arrest and Resuscitation
- Trauma and Emergency Care Studies
- Emergency and Acute Care Studies
- Disaster Response and Management
- Acute Myocardial Infarction Research
- Cardiac electrophysiology and arrhythmias
- Immune Response and Inflammation
- Acute Ischemic Stroke Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Traumatic Brain Injury Research
- Injury Epidemiology and Prevention
- Spinal Fractures and Fixation Techniques
- Cardiac Ischemia and Reperfusion
- Healthcare Technology and Patient Monitoring
- Respiratory Support and Mechanisms
- Infection Control and Ventilation
- Heart Rate Variability and Autonomic Control
- COVID-19 epidemiological studies
- Venous Thromboembolism Diagnosis and Management
- Asthma and respiratory diseases
- Cardiac pacing and defibrillation studies
- Travel-related health issues
- Clinical practice guidelines implementation
- Spine and Intervertebral Disc Pathology
- Trauma Management and Diagnosis
Groene Hart Ziekenhuis
2025
University of Toronto
2013-2024
Health Sciences Centre
2011-2024
Sunnybrook Health Science Centre
2013-2024
Sunnybrook Hospital
2015-2022
Heart and Stroke Foundation
2020
Richard Wolf (Germany)
2018-2019
Leiden University Medical Center
2018-2019
Queen's University
2002-2018
St. Michael's Hospital
2011-2018
Despite advances in defibrillation technology, shock-refractory ventricular fibrillation remains common during out-of-hospital cardiac arrest. Double sequential external (DSED; rapid shocks from two defibrillators) and vector-change (VC) (switching pads to an anterior–posterior position) have been proposed as strategies improve outcomes patients with refractory fibrillation.
We prospectively evaluated a clinical prediction rule to be used by emergency medical technicians (EMTs) trained in the use of an automated external defibrillator for termination basic life support resuscitative efforts during out-of-hospital cardiac arrest. The recommends when there is no return spontaneous circulation, shocks are administered, and arrest not witnessed medical-services personnel. Otherwise, transportation hospital, accordance with routine practice.
<h3>Abstract</h3> <b>Objective</b>: To assess the feasibility and impact of introducing Ottawa ankle rules to a large number physicians in wide variety hospital community settings over prolonged period time. <b>Design</b>: Multicentre before after controlled clinical trial. <b>Setting</b>: Emergency departments eight teaching hospitals Canadian communities (population 10000 3000000). <b>Subjects</b>: All 12777 adults (6288 control, 6489 intervention) seen with acute injuries during two 12...
Relapse after the treatment of acute asthma in emergency room is common (occurring 25 to 30 percent cases) and not accurately predicted by any available measurements. We studied usefulness prednisone reducing this high rate relapse.One hundred twenty-two patients treated for exacerbations were assigned a randomized, double-blind fashion receive at discharge either eight days (the dose being tapered from 40 0 mg per day) or matching placebo. Ninety-three subsequently discharged participated...
Background— Out-of-hospital cardiac arrest (OHCA) is associated with a poor prognosis and poses significant burden to the healthcare system, but few studies have evaluated whether OHCA incidence survival changed over time. Methods Results— A population-based cohort study was conducted, including 34 291 patients >20 years of age who were transported alive emergency department an acute-care hospital from April 1, 2002, March 31, 2012, in Ontario, Canada. Patients life-threatening trauma...
Background Considerable effort has gone into improving outcomes from out-of-hospital cardiac arrest (OHCA). Studies suggest that survival is improving; however, prior studies had insufficient data to pursue the relationship between markers of guideline compliance and temporal trends. The objective study was evaluate trends in OHCA over an 8-year period included implementation 2005 2010 international cardiopulmonary resuscitation (CPR) guidelines. Methods Results This a population-based...
cardiac arrest and survival to hospital discharge following failed resuscitation by defibrillation-trained emergency medical technicians (EMT-Ds), propose an out-of-hospital termination-of-resuscitation (TOR) guideline for EMT-Ds. Methods: A 22-month retrospective review of 700 primary patients in a large services (EMS) system who received exclusively EMT-D care. Results: Seven hundred were identified. Follow-up was obtained 662 cases (94.6%). Of these, 36 (5.4%) achieved return spontaneous...
TLR3 recognizes dsRNAs and is considered of key importance to antiviral host-defense responses. also triggers neuroprotective responses in astrocytes controls the growth axons neuronal progenitor cells, suggesting additional roles for TLR3-mediated signaling CNS. This prompted us search alternative, CNS-borne protein agonists TLR3. A genome-scale functional screening a transcript library from brain tumors revealed that microtubule regulator stathmin an activator TLR3-dependent astrocytes,...
Introduction. Few systems worldwide have achieved the benchmark time of less than 90 minutes from emergency medical services (EMS) contact to balloon inflation (E2B) for patients sustaining ST-segment elevation myocardial infarction (STEMI). We describe a successful EMS approach using combination paramedic and 12-lead electrocardiogram (ECG) software interpretation activate STEMI bypass protocol. Objectives. To determine proportion who met E2B in after institution regional activated primary...