Tong Zou

ORCID: 0000-0003-2918-2488
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Research Areas
  • Acupuncture Treatment Research Studies
  • Healthcare and Venom Research
  • Electron Spin Resonance Studies
  • Blood properties and coagulation
  • Cardiac pacing and defibrillation studies
  • Cardiac Structural Anomalies and Repair
  • Biopolymer Synthesis and Applications
  • Autophagy in Disease and Therapy
  • Iron Metabolism and Disorders
  • Hemoglobinopathies and Related Disorders
  • Myofascial pain diagnosis and treatment
  • Cardiovascular Syncope and Autonomic Disorders
  • Traditional Chinese Medicine Analysis
  • Antifungal resistance and susceptibility
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cancer-related molecular mechanisms research
  • Spaceflight effects on biology
  • Neurological disorders and treatments
  • Hydrogen's biological and therapeutic effects
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Cardiac Ischemia and Reperfusion
  • Viral Infections and Immunology Research
  • Trace Elements in Health
  • Clostridium difficile and Clostridium perfringens research
  • Plant-based Medicinal Research

Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2025

Beijing Hospital
2014-2025

Qingdao University
2025

Beijing Institute of Nanoenergy and Nanosystems
2025

Chinese Academy of Sciences
2025

Beijing Institute of Technology
2025

Suzhou Municipal Hospital
2020

Nanjing Medical University
2020

Guizhou Provincial People's Hospital
2018

Shandong Provincial QianFoShan Hospital
2016

Abstract Background The triglyceride–glucose (TyG) index, a tool for assessing insulin resistance, is increasingly recognized its ability to predict cardiovascular and metabolic risks. However, relationship with trauma surgical patient prognosis understudied. This study investigated the correlation between TyG index mortality risk in surgical/trauma ICU patients identify high-risk individuals improve prognostic strategies. Methods identified requiring trauma/surgical admission from Medical...

10.1186/s12933-024-02293-0 article EN cc-by Cardiovascular Diabetology 2024-06-06

Circular RNAs (circRNAs) have been identified as important regulators in regulating cancer progression. The study aims to investigate the expression of circular RNA_LARP4 (circ LARP4) and clinical significance ovarian (OC).The circ LARP4 was detected a total 78 paired tissue adjacent normal samples using quantitative Reverse Transcription-Polymerase Chain Reaction (qRT-PCR) analyses. chi-square test used assess association between circLARP4 clinical-pathological parameters. Survival plot...

10.26355/eurrev_201811_16250 article EN PubMed 2018-11-01

Cardiovascular disease (CVD) is a major global health concern with increasing incident cases and deaths. Homocysteine (Hcy) has been investigated for its potential association CVD, researchers have debated the extent to which Hcy should be considered risk factor cardiovascular diseases, as only 50% of CVD can explained by classical factors. We conducted prospective cohort study using NHANES 1999–2006 data, analyzing 1,739 US patients aged at least 30 CVD. Cox proportional hazards regression...

10.1186/s12872-024-04317-9 article EN cc-by-nc-nd BMC Cardiovascular Disorders 2024-11-16

Hyperuricemia (HUA) impaires spermatogenesis. This study was carried out, aiming to determine whether butyric acid (NaB) avoids the HUA-induced decline of sperm quality HUA mice were developed through intra-peritoneal injection potassium oxalate combined with intragastric uric (UA) and by tube feeding 300 mg·kg-1·d-1NaB. The effect NaB on reproduction male determined measuring count, motility testosterone content. In addition, TM3 GC-2 cells treated a solution containing 30 mg/dl UA 1mM NaB....

10.1038/s41598-025-95846-6 article EN cc-by-nc-nd Scientific Reports 2025-04-28

Abstract Despite being a serious health condition that significantly increases cardiovascular and metabolic disease risks, sleep apnea syndrome (SAS) remains largely underdiagnosed. While polysomnography (PSG) the gold standard for diagnosis, its clinical application is limited by high costs, complex setup requirements, quality interference. Although wearable devices using photoplethysmography (PPG) have shown promise in SAS detection, their continuous operation demands substantial power...

10.1002/advs.202501750 article EN cc-by Advanced Science 2025-04-29

Ischemic heart disease is a major health threat, resulting in large number of mortalities annually worldwide. Oxidative stress one the main causes cell death during ischemia‑reperfusion (IR) injury. Cyclin dependent kinase inhibitor 1A (known as p21) important protecting tissues against IR injury, however mechanism remains unknown. In present study, oxygen‑glucose deprivation and subsequent reoxygenation (OGD/R) H9c2 heart‑derived myocytes was used model to study myocardial injury vitro....

10.3892/mmr.2018.8382 article EN Molecular Medicine Reports 2018-01-05

Hepatitis C virus (HCV) infection is a leading cause of liver-related mortality. Chronic hepatitis (CHC) frequently associated with disturbances in iron homeostasis, serum and hepatic stores being elevated. Accumulating evidence indicates that chronic HCV suppresses expression hepcidin, key mediator to overload conditions. Since hepcidin mediates degradation ferroportin, basolateral transporter involved the release from cells, diminished probably leads up-regulation ferroportin-1 (Fpn1)...

10.1371/journal.pone.0110658 article EN cc-by PLoS ONE 2014-10-20

Background Subclinical infection of cardiac implantable electronic devices (CIEDs) is a common condition and increases the risk clinical infection. However, there are limited studies focused on stratifying prognostic analysis subclinical CIED Methods Results Data from 418 consecutive patients undergoing replacement or upgrade between January 2011 December 2019 were used in analysis. Among included, 50 (12.0%) detected as positive by bacterial culture pocket tissues. The most frequently...

10.1161/jaha.121.022260 article EN cc-by-nc-nd Journal of the American Heart Association 2021-11-03

To investigate the value of implantable cardiac monitor (ICM) in diagnosis and treatment patients over 60 years old with unexplained syncope.

10.3760/cma.j.cn112148-20230906-00132 article EN PubMed 2024-07-24

Current laboratory examinations for hypercoagulable diseases focus on the biomarker content of activated coagulation cascade and fibrinolytic system. Direct detection physiologically important protease activities in blood remains a challenge. This study aims to develop general approach that enables determination crucial factors plasmin blood. assay is based proteolytic activation an engineered zymogen l-phenylalanine oxidase (proPAO), which specific cleavage sites were between inhibitory...

10.1093/jalm/jfaa060 article EN The Journal of Applied Laboratory Medicine 2020-04-04

Ginsenoside Rg2 Attenuates Ischemia-induced Spinal Cord Injury in RatsTo investigate the pathological mechanism underlying injury caused by ischemia/reperfusion and reperfusion explore role of ginsenoside on to spinal cord, 24 male Sprague Dawley rats underwent a surgical procedure this study.The were divided into 3 groups, group 1-sham operated (n=8), 2-surgical (n=8) 3-surgical ischemia/reperfusion+ginsenoside (n=8).Oxidative stress, apoptosis indices observed if any.Thirty minutes...

10.36468/pharmaceutical-sciences.spl.22 article EN Indian Journal of Pharmaceutical Sciences 2020-01-01

Objective The purpose of this study was to know the clinical characteristics and preliminary application wearable cardioverter-defibrillator (WCD) in China. Methods This multicenter, observational performed by five medical centers from China. A total 54 consecutive patients received WCD June 2018 October 2019 were analyzed. Clinical features, compliance, feedbacks treatment effects collected all patients. Results The mean age at (55.2±17.6) years with 87.0% male. There 31...

10.3760/cma.j.issn.1007-6638.2020.01.008 article EN Chin J Cardiac Arrhyth 2020-02-28
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