A5041393167- Amyotrophic Lateral Sclerosis Research
- Orthopaedic implants and arthroplasty
- Neurogenetic and Muscular Disorders Research
- Liver Disease Diagnosis and Treatment
- Total Knee Arthroplasty Outcomes
- Pneumocystis jirovecii pneumonia detection and treatment
- SARS-CoV-2 and COVID-19 Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Bone health and osteoporosis research
- Thyroid Disorders and Treatments
- Blood properties and coagulation
- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Viral Infections and Outbreaks Research
- Food Quality and Safety Studies
- Chronic Disease Management Strategies
- Clinical Laboratory Practices and Quality Control
- Cardiovascular Health and Risk Factors
- HIV Research and Treatment
- Retinal Diseases and Treatments
- Orthopedic Infections and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Neurological diseases and metabolism
- Viral gastroenteritis research and epidemiology
Guangzhou Center for Disease Control and Prevention
2013-2025
Stryker (United States)
2023-2025
Affiliated Eye Hospital of Wenzhou Medical College
2023-2024
Peking University Third Hospital
2018-2024
Wenzhou Medical University
2023-2024
Peking University
2013-2024
Capital Medical University
2011-2024
Beijing Tongren Hospital
2009-2024
Nanchang University
2023-2024
Cardiff University
2024
Background Cardiometabolic multimorbidity (CMM) has emerged as a prominent public health concern. Hypertensive patients are prone to develop comorbidities. Moreover, the accumulation of visceral adipose tissue is main cause for development cardiometabolic diseases. The index (CMI), lipid product (LAP), adiposity (VAI), and Chinese (CVAI) not only assess mass but also reflect dysfunction. So far, no study been reported evaluate association CMI, LAP, VAI, CVAI with CMM risk in hypertensive...
This study was performed to quantify the expression of Golgi protein-73 (GP73) in healthy controls and patients with liver disease, evaluate correlations between GP73 other serum markers different diseases.Serum measured 478 296 types disease. Quantitative hepatitis B virus (HBV) DNA determined two chronic (CHB) groups. Other fibrosis were group α-fetoprotein (AFP) hepatocellular carcinoma (HCC) group. The these evaluated.The value e antigen (HBeAg)-positive CHB group, HBeAg-negative HCC...
Purpose To explore the clinical value of diffusion kurtosis imaging (DKI) and monoexponential diffusion‐weighted (DWI) for predicting early response to neoadjuvant chemotherapy (NAC) in patients with nasopharyngeal carcinoma (NPC). Materials Methods Fifty‐nine stage III‐IVb NPC underwent four 3.0T MR scans: prior to, on 4th, 21st, 42nd days after NAC initiation. The parameters DKI (corrected coefficient, D; excess K) DWI (apparent ADC) were obtained at first three scans. Statistical methods...
Influenza (flu) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibit similar clinical symptoms, complicating the diagnosis management of these critical infections. Thus, there is an urgent need for rapid on-site detection technologies that can simultaneously detect SARS-CoV-2 influenza A viruses. Here, we have developed first platform combines in situ sampling with immune swabs multichannel surface-enhanced Raman spectroscopy (SERS) simultaneous screening two viruses a...
Abstract Objective To understand the prevalence of hypertension and hyperlipidaemia as well current status glycaemic control its influencing factors among type 2 diabetes mellitus patients in community South China, to provide recommendations for prevention diabetes. Methods Questionnaires, physical examinations laboratory tests were conducted on with who participated National Basic Public Health Service Programme Guangzhou 2020. The chi-square test, t-test multi-factor unconditional logistic...
Hand-foot-and-mouth disease (HFMD) is becoming one of the extremely common airborne and contact transmission diseases in Guangzhou, southern China, leading public health authorities to be concerned about its increased incidence. In this study, it was used an ecological study plus negative binomial regression identify epidemic status HFMD relationship with meteorological variables. During 2008-2012, a total 173,524 confirmed cases were reported, 12 death, yielding fatality rate 0.69 per...
Multimorbidity, individuals suffering from two or more chronic diseases, has become a major health challenge worldwide, especially in populous and prosperous cities, where studies of this phenomenon China are limited. We examined the prevalence, trends, patterns, associated factors multimorbidity 2009 to 2018 among community-dwelling adults Guangzhou, China.
Papillary thyroid carcinoma (PTC) is the most common cancer, accounting for about 85 - 90%. Thyroglobulin (Tg) can be produced by normal follicular epithelial cells and well-differentiated malignant tumor cells. In our study, we investigated correlation of preoperative serum Tg between benign tumors PTC patients. The data 1,074 patients were retrospectively collected, including group (517 cases) (557 cases). Preoperative other function indicators detected chemiluminescence immunoassay...
Abstract Background Chest radiograph can independently predict adverse outcomes in outpatients. We examined the associations of aortic knob width (AKW), ascending length (AAL), and (AAW) from chest x‐ray with death cardiovascular events adults aged 50 above. Methods Participants without disease were included Guangzhou Biobank Cohort Study (2003–2008). AKW, AAL, AAW indexed by body surface area. Aortic enlargement was defined using sex‐ age‐specific thresholds, calculated as average value...
In total knee arthroplasty (TKA), correcting or maintaining coronal alignment is essential for high patient function and satisfaction. However, achieved during surgery frequently changes with standing, possibly reflecting the change in loading varus-valgus that occurs between non-weightbearing weightbearing. Moreover, joint also varies as flexes dynamic activities. While studies have reported intraoperatively TKA surgery, they rarely trace back to surgical choices parameters may predict...
Novel 6-substituted-4-cycloalkyloxy-pyridin-2(1H)-ones were synthesized as non-nucleoside reverse transcriptase inhibitors (NNRTIs), and their biological activity was evaluated. Most of the compounds, especially 26 22, bearing a 3-isopropyl 3-iodine group, respectively, exhibited highly potent against wild-type HIV-1 strains those resistant to (RTIs). The diastereoisomers 26-trans 26-cis separately confirmed with HPLC NOESY spectra. isomers had an about 400-fold more than that 26-cis. pair...
Few studies have investigated the combined impact of healthy lifestyle factors on glycemic control. Our study aimed to examine associations a score (HLS) with control and explore interactive effects among patients type 2 diabetes mellitus (T2DM) in China. This cross-sectional was conducted T2DM based health management residents from Guangzhou, Good defined as fasting plasma glucose < 7.0 mmol/L. HbA1c 7.0% also good sensitivity analysis. The HLS including physical activity, waist...
Because many osteoporotic fractures occur during a fall, understanding the effect of off-axis loads on initiation and propagation microdamage in trabecular bone should provide further insight into biomechanics age-related fractures. Fourteen on-axis cylindrical specimens were prepared from 12 bovine tibiae. Fluorescent stains used to label due sequence compressive torsional damaging loads. The mean decrease Young's modulus was over four times greater than that shear after overload, while...