A5071118199- Mesenchymal stem cell research
- Pluripotent Stem Cells Research
- Viral gastroenteritis research and epidemiology
- Respiratory viral infections research
- Cancer-related molecular mechanisms research
- Cancer-related Molecular Pathways
- Bone fractures and treatments
- RNA Research and Splicing
- Tissue Engineering and Regenerative Medicine
- interferon and immune responses
- Influenza Virus Research Studies
- Immune Response and Inflammation
- Immunotherapy and Immune Responses
- Bacterial Identification and Susceptibility Testing
- Hematopoietic Stem Cell Transplantation
- Mosquito-borne diseases and control
- IL-33, ST2, and ILC Pathways
- Cancer Immunotherapy and Biomarkers
- Diphtheria, Corynebacterium, and Tetanus
- Acne and Rosacea Treatments and Effects
- Lysosomal Storage Disorders Research
- Clostridium difficile and Clostridium perfringens research
- RNA modifications and cancer
- Laser Applications in Dentistry and Medicine
- Mycobacterium research and diagnosis
Universiti Putra Malaysia
2021-2024
Beijing Hospital
2024
Xinxiang Medical University
2024
Liaocheng People's Hospital
2018
Liaocheng University
2018
AllCell (United States)
2018
Jiangsu University
2008-2015
Shandong First Medical University
2013-2015
Affiliated Hospital of Jiangsu University
2014-2015
Beijing Friendship Hospital
2015
Abstract Introduction Mesenchymal stem cells (MSCs) are promising candidates for cell-based therapies. Human platelet lysate represents an efficient alternative to fetal bovine serum clinical-scale expansion of MSCs. Different media used in culture processes should maintain the biological characteristics MSCs during multiple passages. However, bone marrow-derived and adipose tissue-derived have not yet been directly compared with each other under human conditions. This study aims conduct a...
Background Obesity has become a global challenge for public health. It been reported that obesity is associated with chronic inflammation. However, the mechanism inflammation contributes to remains elusive. Methodology/Principal Findings In our study, we found novel CD11c+ dendritic cell subset existed in murine adipose tissues which was immature phenotype. Moreover, as compared lean controls, number of DCs and CD4+IL-17+T cells were higher tissue high fat diet (HFD) mice. Adipose derived...
A multiplex real-time PCR assay was developed to simultaneously detect and discriminate influenza virus subtypes, including novel H1N1 (2009) seasonal H3N2 virus, B respiratory syncytial (RSV) in a single test tube, with detection sensitivity specificity of 99% 100%, respectively, for the four pathogens.
The viral etiologies of UTRIs and LTRIs in children Jinan city were investigated between July 2009 June 2010. Nasal throat swabs collected from 397 with URTIs bronchoalveolar lavage fluid specimens 323 LRTIs. RT-PCR/PCR was used to examine all samples for IFV, PIV, RSV, RV, hMPV, HBoV, CoV, ADV, EV. Viral pathogens detected 47.10% URTI 66.57% samples, the incidence coinfection 5.29% 21.05%, respectively. IFV most common virus URTIs, a detection rate 19.40%, followed by PIV (10.83%), RV...
Meniscus-derived stem cells (MeSCs), a unique type of MSC, have outstanding advantages in meniscal cytotherapy and tissue engineering, but the effects molecular mechanisms PBM on MeSCs are still unclear. We used 660-nm LED light with different energy densities to irradiate six human MeSC samples tested their proliferation rate via cell counting, chondrogenic differentiation capacity DMMB assay, mitochondrial activity MTT gene expression qPCR. The ability, 18 J/cm2 group were greater than...
Our study investigated the epidemiology of respiratory viruses in adult patients with upper tract infection (URTI) between August 2009 and September 2010 Jinan, northern China. Nasal throat swabs (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn>596</mml:mn></mml:math>) were collected from URTIs. Nine respiratory-related viruses, including IFV, PIV, HRV, HMPV, HBoV, HCoV, ADV, RSV, EV, detected all samples by conventional reverse...
A coryneform strain, 06-1773O(T) (=WAL 19168(T)), derived from a groin abscess sample was characterized using phenotypic and molecular taxonomic methods. Comparative analyses revealed more than 3 % divergence of the 16S rRNA gene sequence about 10 partial rpoB type strain Corynebacterium glucuronolyticum. The could also be differentiated C. glucuronolyticum by set properties. DNA-DNA relatedness study between WAL 19168(T) CCUG 35055(T) showed value 13.3 (13.7 on repeat analysis). genotypic...
Background: CD4+CD25+ regulatory T (Treg) cells play a pivotal role in the maintenance of homeostatic balance immune system. The current study was conducted to evaluate prevalence Treg cancer patients and identify possible mechanisms contributing cell expansion. Materials Methods: frequencies CD4+CD25+FOXP3+ peripheral blood mononuclear (PBMCs) 62 25 healthy individuals were determined by flow cytometry. purified CD4+CD25– stimulated with malignant pleural effusion (MPE) or tumor...
T-bet plays an important role in immunoregulation; it induces the differentiation of Th1 together with homeobox transcription factor gene Hlx . Recent studies show that and Th1-associated factors are critical regulating tumor development. However, contributions occurrence development cancer remain unknown. In this study, , Runx3 IFN- γ were measured PBMC from patients gastric correlation between or was assessed. The expression levels IFN - significantly decreased, there a positive addition,...
Extensive clinical efforts have been made to control the severity of dengue diseases; however, morbidity and mortality not declined. Dengue virus (DENV) can infect cause systemic damage in many organs, resulting organ failure. Here, we present a novel report showing tailored stem-cell-based therapy that aid viral clearance rescue liver cells from further during infection. We administered combination hematopoietic stem endothelial progenitor DENV-infected BALB/c mouse model found delivery...
Multiple matrix metalloproteinases have significant roles in tissue organization during lung development, and repair. Imbalance of proteinases may lead to chronic inflammation, changes structure, are also highly associated cancer development. The role MMP20 is not well studied organogenesis, however, it was previously shown be present at high level adenocarcinoma. current study aimed identify the functional properties on cell proliferation motility a adenocarcinoma vitro model, relate...
Hematopoietic stem and progenitor cells (HSPCs) have been used successfully to treat patients with cancer disorders of the blood immune systems. In this study, we tried enrich HSPCs by implanting biomaterials into spatium intermusculare mice hind limbs. Gelatine sponges were implanted then retrieved after 12 days. The presence in migrating (MCs) was detected phenotypically probing CD34 + Sca-1 functionally confirming using colony-forming cell assay assessing long-term reconstitution ability....
Adoptive transfer of natural killer (NK) cells represents a viable treatment method for patients with advanced malignancies. Our team previously developed simple, safe, and cost-effective obtaining high yields pure functional NK from cord blood (CB) without the need cell sorting, feeder cells, or multiple cytokines. We present case 52-year-old female patient diagnosed poorly differentiated stage IVB (T3N2M1) endometrial cancer, who exhibited leukemoid reaction pretreatment thrombocytosis as...
Air pollution is widely recognized as a future biohazard, yet its direct effects on human health, particularly in relation to bone health and vitamin D levels, are inadequately understood. While the detrimental impact respiratory cardiovascular well-documented, correlation with deficiency remains weak.<br /> To explore relationship between air an extensive search of scientific literature was conducted. This comprehensive encompassed databases such PubMed, Cochrane Library, DOAJ, while...
To investigate the value of implantable cardiac monitor (ICM) in diagnosis and treatment patients over 60 years old with unexplained syncope.
Molecular crosstalk between the cellular epigenome and genome converge as a synergistic driver of oncogenic transformations. Besides other pathways, epigenetic regulatory circuits exert their effect towards cancer progression through induction DNA repair deficiencies. We explored this mechanism using camptothecin encapsulated in β-cyclodextrin–EDTA–Fe3O4 nanoparticles (CPT-CEF)-treated HT29 cells model. previously demonstrated that CPT-CEF treatment effectively induces apoptosis cell cycle...
Objective To efficiently isolate human skin fibroblast cells with rapid proliferation and to investigate the multi-lineage differentiation potential of fibroblasts into adipogenic, osteogenic, chondrogenic neurogenic directions. Methods The primary were isolated cultured from tissues. Morphological structures, flow cytometry vimentin staining used identify fibroblasts. Growth curves analysis, mitochondrial karyotype analysis cell state different generations. And finally induced...