A5020240417- Service-Oriented Architecture and Web Services
- Neuroinflammation and Neurodegeneration Mechanisms
- Traumatic Brain Injury and Neurovascular Disturbances
- Orthodontics and Dentofacial Orthopedics
- Semantic Web and Ontologies
- Software System Performance and Reliability
- Graphene research and applications
- Mobile Agent-Based Network Management
- Dental Radiography and Imaging
- Advanced Software Engineering Methodologies
- Distributed systems and fault tolerance
- Caching and Content Delivery
- Nerve injury and regeneration
- Gait Recognition and Analysis
- Outsourcing and Supply Chain Management
- Multi-Agent Systems and Negotiation
- Human Pose and Action Recognition
- Dental Anxiety and Anesthesia Techniques
- Advancements in Battery Materials
- Traumatic Brain Injury Research
- Cloud Data Security Solutions
- Neurogenesis and neuroplasticity mechanisms
- Radiation Effects in Electronics
- Carbon Dioxide Capture Technologies
- 3D Shape Modeling and Analysis
Sichuan University
2020-2024
Chengdu University
2024
Army Medical University
2017-2023
University of Dental Medicine
2023
State Key Laboratory of Oral Diseases
2023
National Clinical Research
2023
Southwest Hospital
2023
Stomatology Hospital
2023
Henan University of Science and Technology
2022-2023
Daping Hospital
2017-2022
Vacuolar sorting protein 35 (VPS35) is a critical component of retromer, which essential for selective endosome-to-Golgi retrieval membrane proteins. VPS35 deficiency implicated in neurodegenerative disease pathology, including Alzheimer9s (AD). However, exactly how loss promotes AD pathogenesis remains largely unclear. expressed various types cells the brain, neurons and microglia. Whereas neuronal plays role preventing neurodegeneration, microglial unknown. Here we provide evidence VPS359s...
Abstract Traumatic brain injury (TBI) can induce cognitive dysfunction due to the regional accumulation of hyperphosphorylated tau protein (p-tau). However, factors that cause p-tau concentrate in specific regions remain unclear. Here, we show AQP4 polarization perivascular astrocytic end feet was impaired after TBI, which most prominent ipsilateral tissue surrounding directly impacted region and contralateral hippocampal CA1 area accompanied by increased local p-tau, changes dendritic spine...
Membrane technology can effectively remove acidic gases (H2S and CO2) from natural gas. Covalent organic frames (COFs) have been widely used as membrane materials due to their large pore size pure properties. This work combines machine learning (ML) molecular simulation (MS) develop a method for rapidly screening discovering high-performance COF-based membranes. The ML model is first trained on MS data, using the structural chemical features obtained 20 calculations inputs. Characteristic...
As most clouds are based on virtualization technology, more and virtual machine images created within data centers. Depending the need of disaster recovery, storage space used for backup would easily sprawl to a TB or PB level with growth images. Unfortunately, different have large amount same segments. Those duplicated segments will lead serious waste resource. Although there is lot work focus deduplication could achieve good result in removing duplicate copies, they not very suitable image...
Purpose: Microglial clearance of axonal debris is an essential response for management traumatic optic neuropathy. Inadequate removal leads to increased inflammation and degeneration after The present study investigated the role CD11b (Itgam) in degeneration. Methods: Western blot immunofluorescence were used detect expression mouse nerve crush (ONC) model. Bioinformatics analysis predicted possible CD11b. Cholera toxin subunit B (CTB) zymosan assay phagocytosis by microglia vivo vitro,...
Tau hyperphosphorylation is a characteristic alteration present in range of neurological conditions, such as traumatic brain injury (TBI) and neurodegenerative diseases. Treatments targeting high-mobility group box protein 1 (HMGB1) induce neuroprotective effects these neuropathologic conditions. However, little known about the interactions between hyperphosphorylated tau HMGB1 neuroinflammation. We established model TBI with controlled cortical impacts (CCIs) by injecting virus encoding...
Purpose: Abnormal angiogenesis is a defining feature in couple of ocular neovascular diseases. The application anti-VEGFA therapy has achieved certain benefits the clinic, accompanying side effects and poor responsiveness many patients. present study investigated role irisin retinal neovascularization. Methods: Western blot quantitative PCR were used to determine expression oxygen-induced retinopathy mice model. pathological inflammation index examined after administration. Primary...
Abstract Using the first-principle calculation method, this study analyzed geometrical properties, electron transfer, magnetic and recovery time of NH 3 molecules pristine, vacancy-defected, doped (N, Al, S, Ti, Cr, Co) arsenene/graphene (As/G) heterostructures. Introducing vacancy defects did not enhance activity As/G heterostructure. However, adsorption ability structure with N, Co atoms on was enhanced. Furthermore, state changed as a result Cr doping. The improvements in absorption...
Virtualized resource renting is a key issue in IaaS (Infrastructure-as-a-Service) cloud systems. Suitable allocation improves utilization and increases profit for application providers. The provider will obtain better revenues according to the Service Level Agreement (SLA), if they rent more virtual resources. However, invest much capital these How many resources rents has become thing applications. This paper addresses reconciliation objectives by proposing profit-driven scheduling method...
To determine the optimal settings for reconstructing buccal surfaces of different tooth types using virtual bracket removal (VBR) technique.
In service-oriented system, by using service selection methods, entities can be dynamically bound to abstract services. Major of current system have assumed that candidate services are independent each other. However, recent research has discovered do correlations which will impact Quality-of-Service (QoS) the composition [9]. This paper outlines service-correlation-aware approach, gives a detailed design, and implements it as an Eclipse plug-in integrates into composite development...
This paper tries to find a deep-learning approach Japanese Animation style transfer that creates animation background images more easily and efficiently so we can reduce the cost workload for industry. Our now builds is based on using Convolutional Neural Networks(CNN) which most popular in image processing tasks. Moreover, limit number of color used output get close an ideal color.
Abstract Background Malocclusion patients, as a population highly concerned with oral health-related quality of life (OHRQoL), are especially at risk developing psychiatric disorders. Since somatic pains frequently accompanied by disorders, growing body research is starting to focus on this comorbidity in the orthodontic patient population. However, relationships among pains, and impaired OHRQoL during treatment remain unknown. Method In current study, scale measurements including pain...
Virtual machine image encapsulates the whole software stack including operating system, middleware, user application and other products. Failure occurred in any layer of will be treated as failure. However, virtual with potential failures can convert to template spread a wide range by means replication. And this paper refer phenomenon "image failure propagation". Usually, patching is widely adopted solution resolve failures. Nevertheless, patches are difficult deliver final users cloud...
In advanced service oriented systems, provider usually provides value-added composite to its consumer through compositing some other component service. Because and services are owned by different organizations have their own objectives, level agreements (SLAs) between them should be negotiated discipline the ways in which provided and, turn, obligation fulfilled services. However, current negotiation approaches for canpsilat efficiently optimize preference of profits as far possible. this...
To prepare the specific monoclonal antibody against N-terminal epitope peptide of anti-mullerian hormone (AMH) and to identify its specificity.Using bioinformatics analysis software predict fragment AMH. Then synthesized four antigenic segments mature region AMH as screening target antigen. Synthesized wholegene.Using prokaryotic expression system abtain recombinant protein. Immunized BALB/c mice with AMH, prepared mouse spleen cells for fusing SP/20 cells. Preparation by hybridoma...