A5080421535- Sepsis Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Chemokine receptors and signaling
- Acupuncture Treatment Research Studies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Lipid metabolism and disorders
- Traditional Chinese Medicine Studies
- Barrier Structure and Function Studies
- Autophagy in Disease and Therapy
- Central Venous Catheters and Hemodialysis
- interferon and immune responses
- Hemophilia Treatment and Research
- MicroRNA in disease regulation
- Pharmacological Effects of Natural Compounds
- Bioactive Natural Diterpenoids Research
- NF-κB Signaling Pathways
- Ginseng Biological Effects and Applications
- Intracerebral and Subarachnoid Hemorrhage Research
- Plant-based Medicinal Research
- Blood Coagulation and Thrombosis Mechanisms
- Inflammatory mediators and NSAID effects
- Bacterial Identification and Susceptibility Testing
- Vagus Nerve Stimulation Research
- Mechanical Circulatory Support Devices
- Curcumin's Biomedical Applications
Zhejiang Chinese Medical University
2013-2024
Zhejiang University
2014-2020
First Affiliated Hospital Zhejiang University
2017
BACKGROUND:This study observed the efficacy of ultrasonic technique with out-of-plane orientation and in-plane guidance in radial artery puncture cannulation intensive care unit (ICU) shock patients to elucidate effect this on security cannulation. MATERIAL AND METHODS:A total 88 ICU patients, randomized into a palpation (control) group an ultrasound (experimental) group, received continuous intravenous sedation analgesia. The underwent using traditional pulsation approach, under apparatus....
Sepsis results in high morbidity and mortality. Immunomodulation strategies could be an adjunctive therapy to treat sepsis. Acupuncture has also been used widely for many years China However, the underlying mechanisms are not well-defined. We demonstrated here that EA preconditioning at ST36 obviously ameliorated CLP-induced intestinal injury permeability reduced mortality of sepsis rats. Moreover, electroacupuncture (EA) pretreatment exerted protective effects on mucosal immune barrier by...
Inflammation contributes to acute pulmonary embolism (APE). However, the contributions of extracellular signal‑regulated protein kinases (ERK) and phosphoinositide 3 kinase/protein kinase B (PI3K/Akt) signaling pathways have not yet been elucidated. The aim this study was examine effects aspirin on ERK PI3K/Akt in a rat model APE evaluate prognostic values brain natriuretic peptide (BNP), troponin (TnT) D‑Dimer. A total 108 Sprague‑Dawley rats were assigned into control, sham, low‑, medium‑...
To observe the effect of electroacupuncture (EA) at ST36 on intestinal mucosal mechanical barrier and expression tight junction (TJ) protein, occludin, in a rat model sepsis.60 male Wistar rats were randomly divided into six groups (n=10 each): Control, Control+EA, CLP (caecal ligation puncture), CLP+EA, CLP+Sham-EA, Sham-CLP. Rats CLP, CLP+EA CLP+Sham-EA underwent modeling sepsis; those Sham-CLP sham surgery Control Control+EA remained unoperated. received verum EA non-traditional...
BACKGROUND: Acute pulmonary embolism (APE) is a disorder involving the circulation resulting from blockage of artery.The present study aimed to investigate effects aspirin on nuclear factor-κB (NF-κB) activity in rat model APE. METHODS:A total 108 healthy male Sprague-Dawley rats were randomly assigned into six groups (n=18 per group): control group, sham operation APE and low-, medium-and high-dose groups.Six, 24, 72 hours after induction APE, given at respective daily dose 150, 300, 600...
Inflammatory response is an important determining factor for the mortality of patients with pulmonary thromboembolism. mediators can promote thrombus formation and increase hemodynamic instability. Urokinase a commonly used drug treatment PTE. The effect urokinase on inflammatory reaction in PTE still unclear. Our study was aimed at evaluating effects intervention combined aspirin rats. Results revealed that large amount infiltrated cells surrounding bronchus, vessels, mesenchyme, even...
Cervical cancer (CC) ranks as the second most common malignancy in women, accounting for more two 2 million deaths every year world. Recently, circular RNAs (circRNAs) have been reported to regulate progression of multiple human tumors; however, whether it involves CC remains largely elusive.Two GEO circRNA expression profiles (GSE102686, GSE113696) were downloaded analyze differentially expressed circRNAs using bioinformatics methods. Expression circ_103973, miR-335 and PPP6C tissues cell...
Objective. To explore the intervention methods of patients with dysuria after performing procedure for prolapse and hemorrhoids (PPH). Methods. 100 cases were randomly divided into experimental control groups. The group received routine nursing care. As comparison, group, on basis conventional care, was treated moxa roll moxibustion 1 hour operation 30 minutes. autonomous urination within h, 2 4 6 8 h catheterization rate two groups observed. Results. median time (8 h) significantly greater...
Traumatic brain injury (TBI) remains one of the leading causes death and disability worldwide. Our previous studies have found that traditional Chinese medicine, Panax notoginseng (P. notoginseng) can reduce cerebral hemorrhage in rats with TBI. Yet, exact mechanism still unclear. According to random number table, 36 SD were randomly divided into six groups: Sham group (negative control group), Model group, PIK inhibitor (positive P. (experimental Rapamycin notoginseng+Rapamycin group). In...
The present study aimed to explore the influence of aspirin on CX3CL1/CX3CR1 signaling pathway in acute pulmonary embolism (APE) rats. Our previous found that was increased APE. However, effect this APE remains unclear. CX3CL1-shRNA adenovirus and CX3CL1-overexpression vector were constructed. Male Sprague-Dawley rats randomly divided into 9 groups (n=10): normal group (group N), sham operation Sham), + ASP), model M), ASP M+A), shRNA M+SH), Sham+Cx3), M+A+SH), M+A+CX3). Arterial pressure...
Electroacupuncture (EA) accelerates intestinal functional recovery in sepsis. The present study investigated ghrelin and receptor (GSH-R) levels during EA rats with acute bowel injury (ABI). Rats were grouped into four groups: Sham, ABI, ABI+EA ABI+GHRA+EA (n=12 per group). ABI was induced by cecal ligation puncture (CLP). on bilateral Zusanli acupoints performed following CLP. GSH-R blocker (GHRA) used CLP but prior to for rats. sacrificed 12 h Serum ghrelin, tumor necrosis factor-α (TNF-α)...
To investigate the effects of postconditioning ischemia on expressions hippocampus neuron autophagy-related proteins LC3-II and Beclin-1 in rats following cerebral reperfusion.A total 128 male Sprague-Dawley were randomly divided into 4 groups: control, ischemia-reperfusion (IR), post-conditioning group (IP), PI3K/Akt inhibitor (LY294002). The rat model was established by improved Pulsinelli four vessel occlusion method. durations across platform escape latent period recorded using water...