- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Bone Tissue Engineering Materials
- Surgical Sutures and Adhesives
- Wound Healing and Treatments
- Tracheal and airway disorders
- Hemostasis and retained surgical items
- Voice and Speech Disorders
- Reproductive System and Pregnancy
- Extracellular vesicles in disease
- Graphene and Nanomaterials Applications
- Dysphagia Assessment and Management
- Luminescence Properties of Advanced Materials
- Advanced Photocatalysis Techniques
- Mesenchymal stem cell research
- Uterine Myomas and Treatments
- Radiation Detection and Scintillator Technologies
- Gynecological conditions and treatments
- Microwave Dielectric Ceramics Synthesis
- Endometriosis Research and Treatment
- Infant Nutrition and Health
- Bone fractures and treatments
- Magnetic Properties and Synthesis of Ferrites
- Synthesis of Tetrazole Derivatives
- Intestinal and Peritoneal Adhesions
Sichuan University
2021-2025
State Key Laboratory of Biotherapy
2021-2025
Jilin University
2023-2024
Jilin Medical University
2023
National Yunlin University of Science and Technology
2023
West China Hospital of Sichuan University
2022
Chengdu University of Technology
2019-2020
Chengdu University of Information Technology
2020
Characterized by their pivotal roles in cell-to-cell communication, cell proliferation, and immune regulation during tissue repair, exosomes have emerged as a promising avenue for "cell-free therapy" clinical applications. Hydrogels, possessing commendable biocompatibility, degradability, adjustability, physical properties akin to biological tissues, also found extensive utility engineering regenerative repair. The synergistic combination of hydrogels holds the potential not only enhance...
Wound dressings that promote quick hemostasis and are highly efficient in healing wounds urgently needed to meet the increase clinical demands worldwide. Herein, a dihydrazide-modified waterborne biodegradable polyurethane emulsion (PU-ADH) oxidized hyaluronic acid (OHA) were autonomously cross-linked form hybrid acid-polyurethane (HA-PU) cryogel by hydrazone bonding at -20 °C. Through its specific macroporous structure (which is approximately 220 μm) constructed aggregated PU-ADH particles...
Endoscopic submucosal dissection (ESD) for gastrointestinal tumors and premalignant lesions needs fluid cushion (SFC) mucosal uplift before dissection, wound care including closure rapid healing postoperatively. Current SFC materials as well and/or methods post-ESD have single treatment effect hold corresponding drawbacks, such easy dispersion, short duration, weak hemostasis insufficient repair function. Thus, designing that can serve both is highly desired, remains a challenge. Herein, we...
Abstract Rapid and effective control of non‐compressible massive hemorrhage poses a great challenge in first‐aid clinical settings. Herein, biopolymer‐based powder is developed for the hemorrhage. The designed to facilitate rapid hemostasis by its excellent hydrophilicity, specific surface area, adaptability shape wound, enabling it rapidly absorb fluid from wound. Specifically, can undergo sequential cross‐linking based on “click” chemistry Schiff base reaction upon contact with blood,...
Abstract Urinary stone is conceptualized as a chronic metabolic disorder punctuated by symptomatic events. It has been shown that the occurrence of calcium oxalate monohydrate (COM) during formation regulated crystal growth modifiers. Although crystallization inhibitors have recognized therapeutic modality for decades, limited progress made in discovery effective modifiers to intervene with disease. In this study, we used metabolomics technologies, powerful approach identify biomarkers...
The recurrence rate for severe intrauterine adhesions is as high 60%, and there still lack of effective prevention treatment. Inspired by the nature uterus, we have developed a bilayer scaffold (ECM-SPS) with biomimetic heterogeneous features extracellular matrix (ECM) microenvironment uterus. As proved subtotal uterine reconstruction experiments, mechanical antiadhesion properties could meet requirement repair. With modification tissue-specific cell-derived ECM, ECM-SPS had ECM signatures...
Abstract Bacterial infections pose a serious threat to human health. While antibiotics have been effective in treating bacterial infectious diseases, antibiotic resistance significantly reduces their effectiveness. Therefore, it is crucial develop new and antimicrobial strategies. Metal–organic frameworks (MOFs) become ideal nanomaterials for various applications due crystalline porous structure, tunable size, good mechanical stability, large surface area, chemical stability. Importantly,...