- Opinion Dynamics and Social Influence
- Statistical Methods and Inference
- Complex Network Analysis Techniques
- Advanced Statistical Methods and Models
- Evolutionary Game Theory and Cooperation
- Drug Transport and Resistance Mechanisms
- Fault Detection and Control Systems
- Cancer therapeutics and mechanisms
- Agriculture and Rural Development Research
- Statistical Methods and Bayesian Inference
- Game Theory and Applications
- Complex Systems and Time Series Analysis
- Advanced Statistical Process Monitoring
- demographic modeling and climate adaptation
- Genetic Mapping and Diversity in Plants and Animals
- Control Systems and Identification
- French Urban and Social Studies
- Urban Transport and Accessibility
- Organic Food and Agriculture
- Gene expression and cancer classification
- Genetics and Plant Breeding
- Census and Population Estimation
- Statistical Methods in Clinical Trials
- Carcinogens and Genotoxicity Assessment
- Cancer Treatment and Pharmacology
Laboratoire Interdisciplinaire Solidarités Sociétés Territoires
2014-2024
Laboratoire d'Ingénierie pour les Systèmes Complexes
2014-2024
Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail
2007-2024
Université Clermont Auvergne
2019-2024
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
1999-2024
Laboratoire de Psychologie Sociale et Cognitive
2016-2024
Centre Hospitalier de Fougères
2003-2024
Université Paris-Saclay
2017-2023
Mathématiques et Informatique Appliquées du Génome à l'Environnement
2011-2023
Centre Hospitalier Universitaire de Montpellier
2021
In , Robert Axelrod wondered in a highly influential paper "If people tend to become more alike their beliefs, attitudes, and behavior when they interact, why do not all such di erences eventually disappear?"Axelrod's question highlighted an ongoing quest for formal theoretical answers joined by researchers from wide range of disciplines.Numerous models have been developed understand under what conditions diversity attitudes can co-exist with the fact that very o en interactions, social...
The authors propose an individual‐based model of innovation diffusion and explore its main dynamical properties. In the model, individuals assign a priori social value to which evolves during their interactions with "relative agreement" influence model. This offers possibility including minority "extremists" extreme very definite opinions. Individuals who give high tend look for information that allows them evaluate more precisely individual benefit adoption. If they is low, neither consider...
We show that a recently proposed model generates accurate commuting networks on 80 case studies from different regions of the world (Europe and United-States) at scales (e.g. municipalities, counties, regions). The takes as input number commuters coming in out each geographic unit matrix flows between units. single parameter follows universal law depends only scale our significantly outperforms two other approaches proposing [1], [2], particularly when units are small municipalities).
This study examines the evolution of Schwartz's Basic Human Values during COVID-19 outbreak, and their relationships with perceived threat, compliance movement restrictions social distancing. An online questionnaire was administered to a heterogeneous sample French citizens (N = 1025) first lockdown related outbreak. Results revealed significant values; conservation value higher outbreak than usual, both self-enhancement openness-to-change values were lower usual. Conservation threat...
Abstract Precise control of chromosome pairing is vital for conferring meiotic, and hence reproductive, stability in sexually reproducing polyploids. Apart from the Ph1 locus wheat that suppresses homeologous pairing, little known about activity genes contribute to cytological diploidization allopolyploids. In oilseed rape (Brassica napus) haploids, amount at metaphase I (MI) meiosis varies depending on varieties haploids originate from. this study, we combined a segregation analysis with...
Background: Many different simulation frameworks, in topics, need to treat realistic datasets initialize and calibrate the system. A precise reproduction of initial states is extremely important obtain reliable forecast from model. Methodology/Principal Findings: This paper proposes an algorithm create artificial population where individuals are described by their age, gathered households respecting a variety statistical constraints (distribution household types, sizes, age head, difference...
Semiparametric generalized additive models are a powerful tool in quantitative econometrics. With response Y, covariates X,T, the considered model is E(Y |X;T) = G{XTβ + α m1(T1) ··· md(Td)}. Here, G known link, and β unknown parameters, m1,…,md (smooth) functions of possibly higher dimensional T1,…,Td. Estimates m1,…,md, α, presented, asymptotic distributions given for both nonparametric parametric part. The main focus paper application bootstrap methods. It shown how can be used bias...
Summary Many cultivated species can escape from fields and colonize seminatural habitats as feral populations. Of these, oilseed rape is a widespread feature of field margins roadside verges. Although considered in several studies, the general processes leading to persistence are still poorly known. Notably, it remains unclear whether these annuals form transient populations resulting mainly seed immigration (either neighbouring or during transport), they show real ability persist through...
Many chemical carcinogens require metabolic activation to form genotoxic compounds in human. Standard vitro genotoxicity assays performed with systems, such as rat liver S9, are recognised lead a high number of false positives. The aim this study was evaluate the suitability differentiated human hepatoma HepaRG cells an model system for detection DNA damage induced by promutagens using comet and cytokinesis-block micronucleus assays. Several were tested, including aflatoxin B1 (AFB1),...
Synthetic amorphous silica (SAS) in its nanosized form is now used food applications although the potential risks for human health have not been evaluated. In this study, genotoxicity and oxidative DNA damage of two pyrogenic (NM‐202 203) precipitated (NM‐200 ‐201) SAS were investigated vivo rats following oral exposure. Male Sprague Dawley exposed to 5, 10, or 20 mg/kg b.w./day three days by gavage. strand breaks seven tissues (blood, bone marrow from femur, liver, spleen, kidney, duodenum,...
Abstract Tipping point dynamics are fundamental drivers for sustainable transition pathways of social-ecological systems (SES). Current research predominantly analyzes how crossing tipping points causes regime shifts, however, the analysis potential from these social and ecological is often overlooked. In this paper, we analyze outcomes that may lead to via a stylized model system composed interacting agents exploiting resources and, by extension, overall ecosystem. Interactions between...
The gut microbiota are increasingly considered as a main partner of human health. Metaproteomics enables us to move from the functional potential revealed by metagenomics functions actually operating in microbiome. However, metaproteome deciphering remains challenging. In particular, confident interpretation myriad MS/MS spectra can only be pursued with smart database searches. Here, we compare data sets 48 individual microbiomes using three interrogation strategies dedicated Integrated...
This paper explores the dynamics of attitude change in two dimensions resulting from social interaction. We add a rejection mechanism into 2D bounded confidence (BC) model proposed by Deffuant et al. (2001). Individuals are characterized two-dimensional continuous attitudes, each associated with an uncertainty u, supposed constant this first study. interact through random pairs. If their attitudes closer than u on both dimensions, or further one dimension and not + δ other dimension, then...
We review recent results for high-dimensional sparse linear regression in the practical case of unknown variance. Different sparsity settings are covered, including coordinate-sparsity, group-sparsity and variation-sparsity. The emphasis is put on nonasymptotic analyses feasible procedures. In addition, a small numerical study compares performance three schemes tuning lasso estimator some references collected more general models, multivariate nonparametric regression.
Despite its biotechnological interest, hybridization, which can result in hybrid vigor, has not commonly been studied or exploited the yeast genus. From a diallel design including 55 intra- and interspecific hybrids between Saccharomyces cerevisiae S. uvarum grown at two temperatures enological conditions, we analyzed as many 35 fermentation traits with original statistical modeling tools. We first showed that, depending on types of trait – kinetics parameters, life-history traits,...
The bounded confidence model and its variants applied to moderate extremist agents exhibit three types of attractors: central clusters, double extreme single clusters. These attractors are observed when the models include a dynamics on uncertainties tending decrease interacting with extremists. We show here that new stationary state appears fixed, for large moderates. In this state, opinions keep fluctuating without clustering, altogether forming stable density which shape changes...
Let $Y$ be a Gaussian vector whose components are independent with common unknown variance. We consider the problem of estimating mean $\mu$ by model selection. More precisely, we start collection $\mathcal{S}=\{S_m,m\in\mathcal{M}\}$ linear subspaces $\mathbb{R}^n$ and associate to each these least-squares estimator on $S_m$. Then, use data driven penalized criterion in order select one among these. Our first objective is analyze performance estimators associated classical criteria such as...
Saccharomyces cerevisiae and S. uvarum are two domesticated species of the sensu stricto clade that diverged around 100 Ma after whole-genome duplication. Both have retained many duplicated genes associated with glucose fermentation characterized by ability to achieve grape must fermentation. Nevertheless, these differ for other traits, indicating they underwent different evolutionary histories. To determine how histories mirrored on proteome, we analyzed genetic variability proteomes...
Abstract This study aims to better understand why farmers do not convert organic farming by studying decision trajectories in a dynamic agent‐based model. In this model, an agent's on transitioning is based the comparison between satisfaction with its current situation and potential alternative strategy. A farmer's was modeled borrowing from Theory of Reasoned Action computed comparing performance over time against practices other which he/she lends great credibility (“important others”)....