A5007352151- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Protein Interaction Studies and Fluorescence Analysis
- Drug Transport and Resistance Mechanisms
- Systemic Lupus Erythematosus Research
- Renal Transplantation Outcomes and Treatments
- Protease and Inhibitor Mechanisms
- Organ Transplantation Techniques and Outcomes
- Nematode management and characterization studies
- Genomics and Phylogenetic Studies
- Renal and Vascular Pathologies
- Plant and Fungal Species Descriptions
- RNA Research and Splicing
- Total Knee Arthroplasty Outcomes
- Congenital Heart Disease Studies
- Circular RNAs in diseases
- Orthopaedic implants and arthroplasty
- Metal complexes synthesis and properties
- Cytokine Signaling Pathways and Interactions
- Microbial Community Ecology and Physiology
- Legume Nitrogen Fixing Symbiosis
- Inflammation biomarkers and pathways
- Healthcare and Venom Research
- Bone Tumor Diagnosis and Treatments
- Systemic Sclerosis and Related Diseases
Harbin Medical University
2022-2024
First Affiliated Hospital of Harbin Medical University
2022-2024
National Laboratory for Superconductivity
2024
First Affiliated Hospital of Jiangxi Medical College
2024
Nanchang University
2011-2024
Chizhou University
2024
Nanjing Medical University
2013-2023
Jiangsu Province Hospital
2013-2023
Jiaxing University
2017-2022
Sichuan Agricultural University
2021
The interaction between farrerol and calf thymus DNA in a pH 7.4 Tris-HCl buffer was investigated with the use of neutral red (NR) dye as spectral probe by UV-vis absorption, fluorescence, circular dichroism (CD) spectroscopy, well viscosity measurements melting techniques. It found that molecules could intercalate into base pairs evidenced decreases iodide quenching effect single-stranded (ssDNA) effect, induced CD changes, significant increases relative denaturation temperature DNA....
Background: Systemic lupus erythematosus (SLE) is chronic autoimmune disease with multiple organ damage and associated poor prognosis high mortality. Identification of universal biomarkers to predict SLE activity challenging due the heterogeneity disease. This study aimed identify indicators that are sensitive specific SLE. Methods: We retrospectively analyzed 108 patients Patients were categorized into without groups on basis index. potential routine novel in predicting using receiver...
Akebia trifoliata is an important multiuse perennial plant that often suffers attacks from various pathogens due to its long growth cycle, seriously affecting commercial value. The absence of research on the resistance ( R ) genes A. has greatly limited progress in breeding resistant varieties. Genes encoding proteins containing nucleotide binding sites (NBSs) and C-terminal leucine-rich repeats (LRRs), largest family genes, are vital for disease resistance. A comprehensive genome-wide...
Abstract Purpose This study aimed to investigate the ability of Al 18 F-NOTA-FAPI PET/CT diagnose pancreatic carcinoma and tumor-associated inflammation with comparison F-FDG PET/CT. Methods Prospective analysis scans 31 patients from 05/2021 05/2022 were analyzed. imaging was performed in who had Ce-CT FDG diagnosis still unclear. Follow-up histopathology or radiographic examination confirmed findings. Radiotracer uptake, diagnostic performance, TNM (tumor-node-metastasis) classifications...
Non-coding RNAs are competing endogenous in the occurrence and development of tumorigenesis; numerous microRNAs aberrantly expressed colon cancer tissues play significant roles oncogenesis metastasis. However, large clinical RNA data lacking to further confirm exact role these tumors. This study aimed ascertain differential expression between normal tissues.RNA sequencing patients with were procured from The Cancer Genome Atlas database; differentially long non-coding RNA, messenger RNAs,...
FAP plays a vital role in myocardial injury and fibrosis. Although initially used to study imaging of primary metastatic tumors, the use FAPI tracers has recently been studied cardiac remodeling after infarction. The aimed investigate application PET/CT human fibrosis its relationship with clinical factors. Retrospective analysis scans twenty-one oncological patients from 05/2021 03/2022 visual uptake myocardium were applying American Heart Association 17-segment model left ventricle....
Abstract Background NAT10 is the firstly recognized RNA acetyltransferase that participates in multiple cellular biological processes and human disease. However, role of N-acetyltransferase 10 (NAT10) ankylosing spondylitis (AS) still poorly elaborated. Methods Fifty-six patients with New-Onset AS, 52 healthy controls (HC), 20 rheumatoid arthritis (RA) 16 systemic lupus erythematosus (SLE) were recruited from The First Afliated Hospital Nanchang University, their clinical characteristics...
Objectives: To determine the prevalence of HIV in Hainan island and molecular epidemiological linkages related to risk factors viral transmission. Methods: A governmental HIV/AIDS surveillance program, serological study was conducted volunteers from several high-risk groups between 1991 2006 province. By phylogenetic reconstruction, we performed a tracing representative subset HIV-1-seropositive individuals diagnosed during this survey. Results: Of 499 752 volunteers, 523 (0.1%) accumulated...
The aim of this study was to identify potential factors associated with insufficient/toxic voriconazole trough concentrations (VTCs) in patients order screen the high-risk population. A total 119 VTCs were obtained from 67 patients. Multivariate regression analysis suggested that insufficient (<1.0 mg/L) significantly younger age and underlying hematological malignancy, toxic (>5.5 lower serum albumin (ALB) level. Receiver operating characteristic curve indicated whose < 47 years population...
Background: Osteosarcoma is a rare type of bone tumor, and this study aimed to assess the clinicopathologic features prognoses osteosarcoma patients. Methods: Clinicopathologic survival data 1025 patients between 2010 2016, 230 2008 2009 were downloaded analyzed from SEER database. Patients’ was using Kaplan-Meier analysis; prognostic factors assessed Cox regression hazards model. The 1-, 3-, 5-year rates estimated with nomogram. Competitive risk models used identify related endpoint events...
Background: Tacrolimus (TAC) is widely used after liver transplantation, but the therapeutic window narrow. Objective: The purpose was to study both donor and recipient CYP3A5*3 genotypes affecting TAC apparent clearance rate (CL/F) investigate a population pharmacokinetic (PPK) model in Chinese transplant recipients for potential starting-dose individualized medication. Methods: A data set of 721 concentrations obtained from 43 adult recipients. PPK analyzed using nonlinear mixed-effects...
Abstract The pine wood nematode (PWN), Bursaphelenchus xylophilus, which in China and East Asia is vectored by Monochamus alternatus, the causal agent of wilt disease Japanese black pine, Pinus thunbergii. vector emergence transmission nematodes through feeding on twigs were monitored during 2004 2005 Nanjing, China. started from late April to end June peaked May early June. There 438 927 adults collected 2005, respectively, approximately 70% beetles emerged peak period. Visual estimation...