A5102007494- Plant Molecular Biology Research
- Genetic diversity and population structure
- Genomics and Phylogenetic Studies
- Plant Reproductive Biology
- Plant Disease Resistance and Genetics
- Genetic Mapping and Diversity in Plants and Animals
- Plant Gene Expression Analysis
- Plant and animal studies
- Evolution and Genetic Dynamics
- Plant Diversity and Evolution
- Chromosomal and Genetic Variations
- Plant and Fungal Species Descriptions
- Plant Taxonomy and Phylogenetics
- Photosynthetic Processes and Mechanisms
- Genetic and phenotypic traits in livestock
- Plant Stress Responses and Tolerance
- Aquaculture disease management and microbiota
- Meat and Animal Product Quality
- Banana Cultivation and Research
- Phytochemistry and Biological Activities
- Cancer-related gene regulation
- Advanced MEMS and NEMS Technologies
- Plant biochemistry and biosynthesis
- Machine Learning in Bioinformatics
- Product Development and Customization
Southwest Jiaotong University
2025
Fujian Agriculture and Forestry University
2019-2024
Chinese Academy of Agricultural Sciences
2024
Sichuan Agricultural University
2021-2024
Sichuan University
2014-2024
West China Hospital of Sichuan University
2024
South China Agricultural University
2023
Experimental Center of Forestry in North China
2023
Anhui Science and Technology University
2023
Anhui University of Science and Technology
2023
Background: Osteosarcoma (OS) is the most common primary bone tumor. The disease has a poor prognosis due to delay in diagnosis and development of metastasis. N6-Methyladenosine (m6A)-related regulators play an essential role various tumors. In this study, comprehensive analysis was conducted elucidate relationship between expression profiles m6A-related molecules clinical outcome OS patients. Materials Methods: Public genome datasets tissue microarray (TMA) cohort were used analyze mRNA...
Wolfberry Lycium, an economically important genus of the Solanaceae family, contains approximately 80 species and shows a fragmented distribution pattern among Northern Southern Hemispheres. Although several herbaceous have been subjected to genome sequencing, thus far, no sequences woody representatives available. Here, we sequenced genomes 13 perennial with focus on Lycium barbarum. Integration other provides clear evidence supporting whole-genome triplication (WGT) event shared by all...
Abstract To improve our understanding of the origin and evolution mycoheterotrophic plants, we here present chromosome-scale genome assemblies two sibling orchid species: partially Platanthera zijinensis holomycoheterotrophic guangdongensis . Comparative analysis shows that mycoheterotrophy is associated with increased substitution rates gene loss, deletion most photoreceptor genes auxin transporter might be linked to unique phenotypes fully orchids. Conversely, trehalase catalyse conversion...
Isodon rubescens (Hemsley) H. Hara (Lamiaceae) is a traditional Chinese medicine plant that has been used to treat various human diseases and conditions such as inflammation, respiratory gastrointestinal bacterial infections, malignant tumors. However, the contents of main active components I. from different origins differ significantly, which greatly affected its quality. Therefore, molecular method identify classify needed. Here, we report DNA sequence chloroplast genome collected Lushan,...
Sheep horns are composed of bone and sheaths, the BMPR1A gene is required for cartilage osteogenic differentiation. Therefore, may have a function related to sheep horn, but its relationship with horn remains unclear. In this study, we first utilized RNA sequencing (RNA-seq) data investigate expression in different tissues breeds sheep. Second, whole-genome (WGS) were used explore functional sites gene. Lastly, allele-specific was explored. Our results indicate that significantly higher...
There has been a large literature in the last two decades affirming adaptive DNA sequence evolution between species. The main lines of evidence are from (i) McDonald-Kreitman (MK) test, which compares divergence and polymorphism data, (ii) phylogenetic analysis by maximum likelihood (PAML) analyzes multispecies data. Here, we apply these tests concurrently to genomic data Drosophila Arabidopsis. To our surprise, >100 genes identified do not overlap beyond random expectation. Because...
Abstract Monocots are a major taxon within flowering plants, have unique morphological traits, and show an extraordinary diversity in lifestyle. To improve our understanding of monocot origin evolution, we generate chromosome-level reference genomes the diploid Acorus gramineus tetraploid Ac. calamus , only two accepted species from family Acoraceae, which form sister lineage to all other monocots. Comparing suggest that is not potential progenitor allotetraploid with subgenomes A, B,...
The environmental adaptation of eudicots is the most reasonable explanation for why they compose largest clade modern plants (>70% angiosperms), which indicates that basal would be valuable and helpful to study their survival ability thrive throughout evolutionary processes. Here, we detected two whole-genome duplication (WGD) events in high-quality assembled Akebia trifoliata genome (652.73 Mb) with 24 138 protein-coding genes based on evidence intragenomic intergenomic collinearity,...
This study focused on identifying bladder cancer (BC)-associated genes, transcription factors (TFs), and microRNAs (miRNAs). Two microarray data sets GSE37815 GSE40355 were utilized to screen common differentially expressed genes (DEGs) associated with BC. Then, functional enrichment analysis was performed for elucidating the involved functions of DEGs. Subsequently, protein–protein interaction (PPI) network submodule PPI analyzed. Finally, regulation relationships TF–DEGs miRNA–DEGs...
Antibiotic-resistant Vibrio alginolyticus becomes a worldwide challenge threatening both human health and food safety. The approach in managing such infection is largely absent, despite the fact that mechanisms of antibiotic resistance have been extensively investigated. Metabolic modulation has documented to be novel improving efficacy. In this study, we characterize metabolic signature V. exposed 0.3 or 0.5 μg/ml ofloxacin (OFX). By profiling metabolome, find bacteria treated by two...
Akebia trifoliata (three-leaf akebia) has long been used as a medicinal herb and the potential to be in diverse ways, especially fruit crop. However, efforts domesticate cultivate new varieties for commercial use are only their infancy. Here, we evaluated genetic diversity of 29 genotypes, which were previously selected from natural population consisting 1447 genotypes exhibiting high resistance fungal diseases smooth peel A. using 85 genome-specific single sequence repeat (SSR) markers. We...
Akebia trifoliata is a newly domesticated perennial fruit tree, and the lack of molecular research on stress resistance seriously affects its genetic improvement commercial value development. Superoxide dismutase (SOD) can effectively eliminate accumulation reactive oxygen species (ROS) during rapid growth plant organs under biotic abiotic stresses, maintaining steady state physiological metabolism. In this study, 13 SODs consisting two FeSODs (FSDs), four MnSODs (MSDs) seven Cu/ZnSODs...
Development of immunity-based strategy to manage bacterial infection is urgently needed in aquaculture due the widespread antibiotic-resistant bacteria. Phagocytosis serves as first line defense innate immunity that engulfs bacteria and restricts their proliferations invasions. However, mechanism underlying regulation phagocytosis not fully elucidated way boost yet explored. In this manuscript, we profiled metabolomes monocytes/macrophages isolated from Nile tilapia, prior after on Vibrio...
Akebia trifoliata is an important multiuse perennial plant that often suffers attacks from various pathogens due to its long growth cycle, seriously affecting commercial value. The absence of research on the resistance ( R ) genes A. has greatly limited progress in breeding resistant varieties. Genes encoding proteins containing nucleotide binding sites (NBSs) and C-terminal leucine-rich repeats (LRRs), largest family genes, are vital for disease resistance. A comprehensive genome-wide...
Growth-regulating factor (GRF) is a kind of transcription unique to plants, playing an important role in the flowering regulation, growth, and development plants. Melastoma dodecandrum member Melastomataceae, with ornamental, medicinal, edible benefits. The identification GRF gene family M. can help improve their character flavor continuous flowering. members were identified from genome, bioinformatics, selective pressure, expression patterns analyzed. results showed that there 20 genes...
Melastomataceae has abundant morphological diversity with high economic and ornamental merit in Myrtales. The phylogenetic position of Myrtales is still contested. Here, we report the chromosome-level genome assembly Melastoma dodecandrum Melastomataceae. assembled size 299.81 Mb a contig N50 value 3.00 Mb. Genome evolution analysis indicated that M. dodecandrum, Eucalyptus grandis, Punica granatum were clustered into clade formed sister group ancestor fabids malvids. We found experienced...
Broussonetia papyrifera (L.) L'Hér. ex Vent. has the characteristics of strong stress resistance, high crude protein content, and pruning tolerance. It is an ecological, economic, medicinal plant. Polyploid plants usually perform better than their corresponding diploid in terms nutrients, active substances, resistance.In this study, leaves, calli, seeds B. were used for tetraploid induction by colchicine. The effect colchicine on was summarized through early morphology, chromosome count flow...
Abstract Auxin plays critical roles in root formation and development. The components involved this process, however, are not well understood. Here, we newly identified a peptide encoding gene, auxin‐responsive endogenous polypeptide 1 ( AREP1 ), which is induced by auxin, mediates development Arabidopsis . Expression of was specific to the cotyledon shoot meristem tissues. Amounts transcripts AREP1‐green fluorescent protein fusion proteins were elevated response indoleacetic acid treatment....
Wheat powdery mildew, caused by the obligate parasite Blumeria graminis f. sp. tritici, severely reduces wheat yields. Identifying durable and effective genes against mildew further transferring them into cultivars is important for finally controlling this disease in production. Pm40 has been widely used breeding programs Southwest China due to spectrum potentially resistance mildew. In present study, a test demonstrated that still Bgt race E20. We identified cloned TraesCS7B01G164000 with...