A5100672268- Lung Cancer Treatments and Mutations
- Functional Brain Connectivity Studies
- Lung Cancer Research Studies
- Cancer Genomics and Diagnostics
- RNA modifications and cancer
- Advanced Neuroimaging Techniques and Applications
- Neuroendocrine Tumor Research Advances
- Phytochemicals and Antioxidant Activities
- Cancer Immunotherapy and Biomarkers
- Child and Adolescent Psychosocial and Emotional Development
- Neural dynamics and brain function
- Reading and Literacy Development
- Electrolyte and hormonal disorders
- Cancer-related molecular mechanisms research
- Resilience and Mental Health
- Attention Deficit Hyperactivity Disorder
- Gene Regulatory Network Analysis
- Colorectal Cancer Treatments and Studies
- Cancer, Hypoxia, and Metabolism
- Neural and Behavioral Psychology Studies
- Gastric Cancer Management and Outcomes
- RNA regulation and disease
- Lung Cancer Diagnosis and Treatment
- Herpesvirus Infections and Treatments
- Personality Traits and Psychology
Beijing Normal University
2017-2025
Capital Medical University
2014-2025
Zhengzhou University
2023-2025
Beijing Chest Hospital
2016-2025
Leiden University
2024
Xiaomi (China)
2024
Soochow University
2024
Xuzhou Medical College
2024
Sichuan University
2024
China Animal Disease Control Center
2017-2024
The default-mode network (DMN) is a set of functionally connected regions that play crucial roles in internal cognitive processing. Previous resting-state fMRI studies have demonstrated the intrinsic functional organization DMN undergoes remarkable reconfigurations during childhood and adolescence. However, these mainly focused on cross-sectional designs with small sample sizes, limiting consistency interpretations findings. Here, we used large longitudinal data comprising 305 typically...
In an increasingly aging society, it is of great importance to consider trajectories subcortical volumes at different ages for understanding biological markers aging. Thus, we investigated sex, age, and their interactions on volumes, including the basal ganglia (caudate, putamen, accumbens, pallidum), thalamus, hippocampus, amygdala.We analyzed adult lifespan trajectory asymmetries in 563 healthy subjects aged from 19 86 using magnetic resonance imaging (MRI) data publicly available 7IXI...
In the present study, antiproliferative effect of dioscin on human gastric carcinoma SGC-7901 cells was confirmed by 3-(4, 5-dimethylthiahiazo-zyl)-2, 5-dip-henytetrazolium bromide and flow cytometry assays. Through acridine orange-ethidium double fluorescent staining, apoptotic morphology observed. Radioimmunoassays showed that tumor necrosis factor (TNF)-α concentration in treated with significantly increased compared untreated cells. Several proteins mRNA related to mitochondrial death...
Adenoid cystic carcinoma of the lung (ACCL) is a rare salivary gland-type malignant neoplasm that occurs infrequently as primary tumor airway. Owing to its low incidence, clinicopathological features, immunohistochemical expression spectrum, treatment and long-term survival have not been fully elucidated. The present study retrospectively assessed clinical characters, strategy 34 patients diagnosed with ACCL at Beijing Chest Hospital, Capital Medical University (Beijing, China) between...
MaPa, which was combined by strong interaction, used in the extraction of HT from olive leaves combination with ultrasound treatment. The MaPa extract had good biocompatibility and excellent antioxidant, bacteriostatic anti-inflammatory effects.
Background: Immune checkpoint inhibitors (ICIs) hold a great promise in treatment of non-small cell lung cancer (NSCLC), while only portion patients benefited from the treatment, and others could not achieve optimal therapeutic effects initial immunotherapy, even for those with PD-L1 (Programed death ligand 1) tested positive. However, clinical markers selection who will benefit ICIs combination beforehand are largely unknown. Objectives: The purpose this study was to explore non-invasive...
From childhood to adolescence, the structural organization of human brain undergoes dynamic and regionally heterogeneous changes across multiple scales, from synapses macroscale white matter pathways. However, during this period, developmental process multiscale architecture, its association with cortical morphological changes, role in maturation functional remain largely unknown. Here, using two independent multimodal imaging datasets aged 6–14 years, we investigated by constructing an vivo...
A concise synthesis of benzodiazepines via Rh(III) catalyzed C-H activation/ [4 + 3] annulation easily available 1-arylpyrazolidinones with allylic acetal has been developed. The was employed as a novel 3C synthon in this transformation. Benzodiazepines were built under mild reaction conditions high efficiency and chemoselectivity. atom-economy accessible substrates reveal potential application.
Abstract Functional brain networks require dynamic reconfiguration to support flexible cognitive function. However, the developmental principles shaping network dynamics remain poorly understood. Here, we report longitudinal development of large-scale during childhood and adolescence, its connection with gene expression profiles. Using a multilayer model, show temporally varying modular architecture child networks, higher switching primarily in association cortex lower primary regions. This...
Attention and reading are essential skills for successful schooling in adult life. While previous studies have documented that attention development supports acquisition, whether how learning to read may improve among school-age children the brain structural functional be involved remain unknown. In this prospective longitudinal study, we examined bidirectional predictions between neural mediators of using cross-lagged panel modeling. The results showed better baseline performance...
Berberine, a constituent of some traditional Chinese medicinal plants, has been reported to have cytotoxicity effects on different human cancer cell lines. There is no available information about the and mechanism ... | Find, read cite all research you need Tech Science Press
The H9N2 subtype of avian influenza virus (AIV) is widely prevalent in poultry and wild birds globally, has become the predominant circulating China. AIV can directly or indirectly (by serving as a "donor virus") infect humans, posing significant threat to public health. Currently, there lack in-depth research on prevalence viruses Shanxi Province, central In this study, we isolated 14 AIVs from October 2020 April 2022 genetic analysis revealed that these belonged seven different genotypes....
We tested the factorial invariance of Satisfaction with Life Scale (SWLS) across 2,178 rural, urban, and rural-to-urban Chinese adolescent students from middle schools universities. examined psychometric properties SWLS a 1-factor model each groups. Multigroup analysis results revealed configural, weak, strong, strict groups, also invariance, covariance, latent mean invariance. The showed that had high internal consistency reliability supported single-factor structure. In addition, they gap...
Young lung cancer as a small subgroup of has not been fully studied. Most the previous studies focused on clinicopathological features, but molecular characteristics are still few and limited. Here, we explore prognosis variation in young patients with NSCLC. A total 5639 samples (NSCLC, age ≤40) were screened from SEER same number old ≥60) by propensity score matching to evaluate two groups. 165 treatment-naïve diagnosed NSCLC enrolled feature difference between age-varying CCLE cell line...
The study aimed to explore the relationship among negative academic emotions (e.g., anxiety, shame, anger, boredom, hopelessness, disappointment, and hatred), psychological well-being (including life vitality, health concern, altruism commitment, self-value, friendly relationship, personal development), cognitive reappraisal in rural-to-urban migrant adolescents China. Specifically, it was hypothesized that between is moderated by reappraisal. A total of 311 aged 14–20 years were selected,...
Purpose: Although alterations in resting-state functional connectivity between brain regions have been reported children with attention-deficit/hyperactivity disorder (ADHD), the spatial organization of these changes remains largely unknown. Here, we studied frontal-parietal attention network topology ADHD, and related to a clinical measure disease progression. Methods: Resting-state fMRI scans were obtained from New York University Child Study Center, including 119 ADHD (male n= 89; female...
Background: Previous findings indicate that stress has a profound influence on suicide behavior, but the potential mediating and moderating mechanisms are unknown between uncertainty behavior. The present study, therefore, examined relationship effect of depressive symptoms, family in sample university students China. Methods: 1828 were assessed anonymously by using Uncertainty Stress Scale, Center for Epidemiologic Studies Depression Brief Suicidal Family Relationship Scale May to June...