A5050409658- Circadian rhythm and melatonin
- Pluripotent Stem Cells Research
- Epigenetics and DNA Methylation
- CRISPR and Genetic Engineering
- Immune Cell Function and Interaction
- Bioactive Natural Diterpenoids Research
- T-cell and B-cell Immunology
Medical University of Vienna
2019
National Centre for Biological Sciences
2015
Institute for Stem Cell Biology and Regenerative Medicine
2012
Abstract Factor induced reprogramming of fibroblasts is an orchestrated but inefficient process. At the epigenetic level, it results in drastic chromatin changes to erase existing somatic “memory” and establish pluripotent state. Accordingly, alterations regulators including Ezh2 influence iPSC generation. While role individual transcription factors resetting landscape during generation increasingly evident, their engagement with modulators remains be elucidated. In current study, we...