- Advanced Queuing Theory Analysis
- Advanced Wireless Network Optimization
- Network Traffic and Congestion Control
- Ferroptosis and cancer prognosis
- RNA modifications and cancer
- Advanced Bandit Algorithms Research
- Transportation Planning and Optimization
- Probability and Risk Models
- Cancer-related molecular mechanisms research
- Immune cells in cancer
- Glioma Diagnosis and Treatment
- Blockchain Technology Applications and Security
- Supply Chain and Inventory Management
- Wireless Communication Networks Research
- Optimization and Search Problems
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Transportation and Mobility Innovations
- Healthcare Operations and Scheduling Optimization
- Distributed systems and fault tolerance
- Privacy-Preserving Technologies in Data
- Advanced Graph Neural Networks
- Extracellular vesicles in disease
- Age of Information Optimization
- Software System Performance and Reliability
- Machine Learning in Healthcare
University of Hong Kong
2016-2025
Hangzhou Medical College
2022-2025
Zhejiang Provincial People's Hospital
2022-2025
Hong Kong University of Science and Technology
2016-2025
Fuzhou University
2023-2025
Harbin Medical University
2022-2024
Second Affiliated Hospital of Harbin Medical University
2022-2024
Fudan University
2024
Zhuhai Fudan Innovation Research Institute
2024
Hainan University
2024
Abstract Aims Neutrophil extracellular traps (NETs) have been implicated in thrombotic diseases. There is no definitive explanation for how NETs form during acute ischemic strokes (AIS). The purpose of our study was to investigate the potential mechanism and role formation AIS process. Methods As well as 45 healthy subjects, patients with had ELISA tests performed detect NET markers. Expression high-mobility group box 1 (HMGB1) on platelet microvesicles (PMVs) analyzed by flow cytometry...
Balancing the Abandonment and Cancellation of a Ride-Matching Market. In “On-Demand in Spatial Model with Cancellation,” Wang, Zhang, Zhang propose spatial model to approximate pickup times based on number waiting passengers idle drivers. They analyze dynamics drivers queueing which platform can control matching process by setting threshold expected time. Applying fluid approximations, we obtain accurate performance evaluations an elegant optimality condition they policy that adapts...
Neutrophil extracellular traps (NETs) contribute to the creation of a coagulation state in various diseases. Currently, it is not clear whether NETs are present thrombi and plasma patients with cerebral venous sinus thrombosis (CVST). This study aimed investigate presence blood samples from CVST procoagulant activity (PCA) during progression CVST.Thrombi obtained undergoing thrombectomy were examined by immunochemistry using neutrophil elastase (NE), CD66b citrullinated histone H3(citH3)....
5-Methylcytosine (m5C) methylation is an important RNA modification pattern that can participate in oncogenesis and progression of cancers by affecting stability, expression oncogenes, the activity cancer signaling pathways. Alterations long non-coding RNAs (lncRNAs) are potentially correlated with abnormalities m5C regulation features cancers. Our aim was to reveal mechanisms which lncRNAs regulated process, explore impact aberrant on biological properties lower-grade gliomas (LGG),...
In “Dynamic Scheduling of Multiclass Many-Server Queues with Abandonment: The Generalized cμ/h Rule,” Long, Shimkin, Zhang, and Zhang propose three scheduling policies to cope any general cost functions patience-time distributions. Their first contribution is introduce the target-allocation policy, which assigns higher priority customer classes larger deviation from desired allocation service capacity prove its optimality for queue-length Gcμ/h rule, extends well-known Gcμ rule by taking...
Problem definition: We study customer service chat (CSC) systems, in which agents can serve multiple customers simultaneously, with generally distributed and patience times. The multitasking capability of introduces idiosyncratic challenges when making routing staffing decisions. Methodology/results: To determine the dynamic matching arriving available agents, we first formulate a linear program (LP) based on system primitives. Inspired by optimal solution LP, design parsimonious policy that...
Motivated by applications in computer and communication systems, we consider a processor-sharing queue where the number of jobs served is not larger than K. We propose measure-valued fluid model for this limited show that there exists unique associated solution. In addition, arises as limit sequence appropriately scaled queues.
We consider customer service chat (CSC) systems where customers can receive real time from agents using an instant messaging (IM) application over the Internet. A unique feature of these is that serve multiple simultaneously. The number agent serving determines rate at which each assigned to receives service. staffing problem in CSC with impatient objective minimize while providing a certain level. level measured terms proportion who abandon system long run. First we propose effective...
In addition to traditional call centers, many companies have started building a new kind of customer contact center, in which agents communicate with customers via instant messaging (IM) over the Internet rather than phone calls. A distinctive feature service centers based on IM is that one agent can serve multiple parallel. We choose model such center as server pool consisting limited processor-sharing servers. characterize underlying stochastic processes by establishing fluid approximation...
This paper presents a novel framework for multi-armed bandit problems with side-observations and switching constraints, which arises in range of real-world applications such as robotic. To address the challenges effectively utilizing graph-structured observations while adhering to graph we design graph-agnostic graph-aware algorithms tailored this new setting. Specifically, our algorithm selects nodes highest upper confidence bound without prior knowledge feedback probabilities, minimizing...
Data has revealed a noticeable impact of delay-time-related information on phone-customers; for example and somewhat surprisingly, delay announcements can abruptly increase the likelihood to abandon (hang up). Our starting point is that latter phenomena be used support control queue lengths delays. We do so by timing appropriately determining staffing levels accordingly. To this end, we model service system as an overloaded GI/M/s + GI queue, in which seek minimize number servers, s, subject...
Recommendation systems aim to predict users' feedback on items not exposed them yet. Confounding bias arises due the presence of unmeasured variables (e.g., socio-economic status a user) that can affect both user's exposure and feedback. Existing methods either (1) make untenable assumptions about these or (2) directly infer latent confounders from exposure. However, they cannot guarantee identification counterfactual feedback, which lead biased predictions. In this work, we propose novel...