A5035302966- Hematopoietic Stem Cell Transplantation
- Acute Lymphoblastic Leukemia research
- Acute Myeloid Leukemia Research
- Cytomegalovirus and herpesvirus research
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Chronic Lymphocytic Leukemia Research
- Chronic Myeloid Leukemia Treatments
- Multiple Myeloma Research and Treatments
- Polyomavirus and related diseases
- Herpesvirus Infections and Treatments
- Orthodontics and Dentofacial Orthopedics
- Temporomandibular Joint Disorders
- Neurological Complications and Syndromes
- Toxoplasma gondii Research Studies
- Dental Radiography and Imaging
- dental development and anomalies
- Brain Metastases and Treatment
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Sexual Differentiation and Disorders
- Respiratory viral infections research
- Microscopic Colitis
- Lung Cancer Research Studies
- Cancer Treatment and Pharmacology
- Renal and related cancers
Ospedale Santa Maria della Misericordia di Udine
2025
University of Illinois Chicago
2024
Policlinico San Matteo Fondazione
2014-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2015-2024
University of Milan
1991-2022
A. O. Ordine Mauriziano di Torino
2022
Luigi Sacco Hospital
2022
University of Pavia
1999-2021
University of Trieste
2019-2021
Foundation Center
2021
The influence of occlusal conditions on stomatognathic function can be assessed by electromyography. Electromyographic activity left and right temporal masseter muscles was recorded in 30 young healthy adults with a normal occlusion during: (1) 3‐s maximum voluntary clench cotton rolls positioned the posterior teeth (standardization recording); (2) intercuspal position; (3) alternate ‘maximum’ contraction relaxation 1 Hz frequency. All potentials were standardized as percentage potential...
Letermovir (LMV) inhibits HCMV replication by binding to components of the HCMV-terminase complex showing a potential role in prevention HCMV-related complications allogenic hematopoietic stem cell transplant recipients (allo-HSCTRs). However, little is known about breakthrough infection and relevance DNAemia during prophylaxis. We reported results multicenter prospective study involving five Italian centers management 75 adult HCMV-seropositive allo-HSCTRs undergoing LMV The aim present was...
The aim of this study was to analyze the clinical, radiologic, and biological features associated with human herpesvirus 6 (HHV-6) encephalitis in immunocompetent immunocompromised hosts establish which clinical settings should prompt HHV-6 testing.We performed a retrospective research virology database Fondazione IRCCS Policlinico San Matteo (Pavia, Italy) for all patients who tested positive DNA CSF and/or blood from January 2008 September 2018 separately assessed number meeting criteria...
Letermovir (LTV), recently approved for the prophylaxis of human cytomegalovirus (HCMV) reactivation after hematopoietic stem cell transplantation (HSCT), has been shown to decrease rate infection in first months post-transplantation. The aim this study was evaluate impact LTV on immune reconstitution and late-onset infection. We studied HCMV HCMV-specific T 2 matched groups HSCT recipients, those treated with (n = 30; group) receiving preemptive therapy 31; PET group). analyzed rates...
Sequential nasopharyngeal aspirates from patients without respiratory symptoms undergoing hematopoietic stem cell transplantation (HSCT) were tested for genomic RNA of human metapneumovirus (hMPV). Persistent hMPV infection was documented in most them and confirmed by virus isolation. etiology also evaluated during the same period samples pediatric with acute diseases (ARDs). Sequence analysis HSCT recipients genotype A strong interhost similarity; this pattern differs that observed ARDs....
This study aims to measure the values of spleen stiffness (SS) in healthy subjects, inter-operator agreement SS measurement, and detect statistically significant correlations between age, sex, weight, BMI, portal vein dynamics splenic dimensions.The included 100 volunteers who had no substantial alcohol intake (<30g/daily for man, <20g/daily women), were negative on hepatitis B, C, HIV blood serology, any history lymphoproliferative disorders. Abdominal ultrasound, liver elastography...
We performed a nationwide registry-based analysis to describe the clinical outcome of adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) who underwent an allogeneic hematopoietic stem cell transplantation (HSCT) after tyrosine kinase inhibitor (TKI)-based treatment A total 441 were included in study. The median age at HSCT was 44 years (range, 18 70 years). All (100%) received TKI before (performed between 2005 and 2016). Of these patients, 404 (92%)...
The relative contribution of human cytomegalovirus (HMCV)-specific CD4(+) and CD8(+) T cells to the control HCMV infection in hematopoietic stem cell transplant (HSCT) recipients is still controversial. reactivation HCMV-specific reconstitution were monitored for 1 year 63 HCMV-seropositive patients receiving HSCT. was detected all but 2 patients. In 20 (31.7%) (group 1) resolved spontaneously, whereas 32 (50.8%) 2) controlled after a single short-course pre-emptive therapy remaining 9...
Currently, no consensus has been reached on the optimal blood compartment to be used for surveillance of cytomegalovirus (CMV) and Epstein-Barr virus (EBV) DNAemia. Although several comparative studies have performed correlating CMV EBV DNA loads in whole (WB) versus plasma, our knowledge, date analyzed kinetics both viruses 2 compartments. In this retrospective noninterventional multicenter cohort study, 121 hematopoietic stem cell transplantation (HSCT) recipients were investigated by...
In 13 healthy subjects (eight men and five women, mean age, 22 years), an aluminum intercuspal interference (height, 0.25 mm) was placed on the maxillary right first premolar to study its effect contractile symmetry of left masseter anterior temporalis muscles when measured through a Percentage Overlapping Coefficient (POC), derived from surface electromyographic recordings maximum voluntary teeth clenching. Additionally, estimate potential experimental induce lateral displacement mandible,...
Options for relapsed/refractory indolent lymphoma include chemotherapy, immunotherapy and high-dose therapy with autologous support. The best combination of these approaches, however, is not defined. We treated 10 patients follicular (n = 7) or mantle cell 3) using immunotherapy, autotransplant in a sequence four phases, each designed to play specific role tumour eradication. After the debulking VACOP-B (doxorubicin, cyclophosphamide, etoposide, vincristine, prednisone, bleomycin) (phase 1),...
Background. This study aims to determine the incidence and outcome of nephrotic syndrome in patients who underwent allogeneic stem cell transplantation a single center. Methods. Records 279 adult with hematological diseases hematopoietic were analyzed evaluate syndrome. The diagnosis chronic graft-versus-host disease was based on clinical evidence histological confirmation whenever possible. Results. Of patients, 105 minimum follow-up 100 days developed disease: six these had cumulative 8%...
The 3-dimensional (3-D) inclination of the facial axis clinical crown (FACC) and size crowns were measured in 100 white northern Italians. subjects consisted 22 girls 21 boys, ages 13-15 years (adolescents), 31 women 26 men, 16-26 (adults), all with a complete permanent dentition Class I dental relationships. 3-D coordinates landmarks obtained computerized electromagnetic digitizer. Clinical heights FACC inclinations anatomical frontal sagittal planes relative to 2 reference planes,...
AbstractBackground : Although anti-endomysial antibodies (EmA) have been found in the supernatants of cultured intestinal mucosa from patients with coeliac disease (CD), no study has clinical reliability this new diagnostic tool investigated. Our aims were to evaluate usefulness vitro production EmA CD diagnosis consecutive suspected CD, and challenge on a gluten-free diet (GFD). Methods For former aim, who due undergo biopsy for enrolled; according final diagnosis, these divided into two...
SLE is an autoimmune disorder that involves polyclonal autoimmunity against multiple autoantigens. PTX3, a marker of the acute-phase inflammatory response, plays important role in innate immunity and modulation adaptive immune response. Our study tried to resolve some rather controversial aspects use PTX3 as biomarker disease activity patients. We demonstrated plasma concentration patients was significantly higher than healthy control groups reflected activity. ROC curve analysis used...
In Brief Background Neurological complications (NC) after hematopoietic stem cell transplantation (HSCT) are rare events. The evolution of transplant procedures has resulted in improved survival and allowed elderly patients or those with comorbidity to receive an HSCT. risk NC these still not been well defined. Therefore, we carried out observational study estimate the occurrence identify risks associated NC. Methods cohort included 452 adult-allogeneic HSCT recipients, transplanted from...