A5102868005- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Cardiomyopathy and Myosin Studies
- Cardiac Valve Diseases and Treatments
- Cardiovascular Effects of Exercise
- Congenital Heart Disease Studies
- Cardiovascular Disease and Adiposity
- Cardiac Structural Anomalies and Repair
- Viral Infections and Immunology Research
- Sports injuries and prevention
- Cardiovascular Health and Disease Prevention
- Cardiovascular and exercise physiology
- Cardiac Arrest and Resuscitation
- Coronary Artery Anomalies
- Heart Failure Treatment and Management
- Sirtuins and Resveratrol in Medicine
- Aortic Disease and Treatment Approaches
- Cardiac pacing and defibrillation studies
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2025
Beijing Anzhen Hospital
2023-2025
Capital Medical University
2023-2025
Fu Wai Hospital
2020-2022
Peking Union Medical College Hospital
2018
BACKGROUND: Current guidelines recommend implantable cardioverter defibrillators for the primary prevention of sudden cardiac death (SCD) in patients with dilated cardiomyopathy left ventricular ejection fraction (LVEF)≤35%. However, its effectiveness is hindered by inability to reliably discriminate between risk SCD and competing heart failure deterioration, thereby limiting clinical utility. We aimed refine stratification model based on magnetic resonance imaging LVEF≤35%. METHODS: A total...
Background Assessment of subclinical myocardial dysfunction by using feature tracking has shown promise in prognosis evaluation heart failure with preserved ejection fraction (HFpEF). Global early diastolic longitudinal strain rate (eGLSR) can identify earlier dysfunction; however, limited data are available on its prognostic value HFpEF. Purpose To evaluate the association between left ventricular (LV) eGLSR and primary composite outcomes (all-cause death or hospitalization) patients...
Background: Cardiac magnetic resonance (CMR) has been shown to improve the diagnosis of myocarditis, but no systematic comparison this technique is currently available. The purpose study was compare 2009 and 2018 Lake Louise Criteria (LLC) for acute myocarditis using 3.0 T MRI with endomyocardial biopsy (EMB) as a reference provide cutoff values multiparametric CMR techniques. Methods: A total 73 patients (32 ± 14 years, 71.2% men) clinically suspected undergoing EMB were enrolled in study....
Despite current recommendations for heart failure with preserved ejection fraction (HFpEF), few studies have demonstrated the ability of MRI to identify subtle functional differences between HFpEF essential hypertension (HFpEF-HTN) patients and (HTN).This study aimed detect evaluate in HTN using feature-tracking (FT) ascertain optimal strain cutoffs diagnosis HFpEF-HTN.Retrospective study.Three groups (84 HFpEF-HTN; 72 HTN; 70 healthy controls).1.5T, steady-state free precession (SSFP),...
Abstract The clinical features, CMR characteristics and outcomes of arrhythmogenic left ventricular cardiomyopathy (ALVC), which is a very rare nonischemic cardiomyopathy, are currently not well studied. purpose the study to investigate cardiovascular magnetic resonance (CMR) imaging (ALVC). Fifty-three consecutive patients with ALVC were divided into two groups: without right (RV) involvement (n = 36, group 1) those RV 17, 2). Clinical symptoms, cardiac electrophysiological findings,...
Background Left and right cardiac structures have been shown to provide important prognostic information in patients with various disorders. They always biomarkers heart failure are crucial the judgment of a variety diseases. Purpose To age‐ sex‐specific reference values normal structure Chinese adults. Study Type Prospective study. Population In all, 200 healthy adult volunteers 20 men women each five age deciles from 70 years. Field Strength 3.0T, steady‐state free precession ( SSFP ),...
Purpose Several adults with repaired tetralogy of Fallot (rToF) undergo pulmonary valve replacement (PVR) to reduce the right ventricular volume and retain function. However, there is currently no consensus on ideal time for PVR surgery in asymptomatic patients rTOF regurgitation (PR). Clinical outcomes after are also indeterminate. Recently, myocardial strain rate derived from cardiac magnetic resonance (CMR) feature tracking were found be more sensitive dysfunction than conventional...
This preclinical study has established that chronic coronary artery stenosis can induce significant myocyte loss with modest global replacement fibrosis leads to LV dysfunction and varying degrees of congestive heart failure.
Background Diabetes mellitus (DM) is associated with an increased risk of cardiovascular disease (CVD). Hence, early detection cardiac changes by imaging crucial to reducing complications. Purpose Early The study aimed detect the dynamic change in morphology, function, and diffuse myocardial fibrosis(DMF) T1DM T2DM mice models. Materials methods 4-week-old C57Bl/6J male were randomly divided into control (n=30), (n=30) groups. A longitudinal was conducted every 4 weeks using serial 7.0T CMR...
Background: The pathophysiology of the obese HFpEF population were less understood. This study aimed to investigate clinical features and cardiovascular magnetic resonance (CMR) derived myocardial strain tissue characteristics in heart failure with preserved ejection fraction (HFpEF) phenotype.Methods: We consecutively included a total 280 participants including 108 patients, 50 normal-weight 72 subjects, controls who underwent CMR. Clinical CMR structural functional parameters...