A5034379992- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
- Cholesterol and Lipid Metabolism
- Vitamin D Research Studies
- Peroxisome Proliferator-Activated Receptors
- Spondyloarthritis Studies and Treatments
- Organic Chemistry Cycloaddition Reactions
- Asymmetric Synthesis and Catalysis
- Hepatitis C virus research
- Adipokines, Inflammation, and Metabolic Diseases
- Synthesis and Catalytic Reactions
- Lipid metabolism and disorders
- Caveolin-1 and cellular processes
- Menstrual Health and Disorders
- Biliary and Gastrointestinal Fistulas
- Immune Cell Function and Interaction
- Adrenal Hormones and Disorders
- Wireless Power Transfer Systems
- Tendon Structure and Treatment
- Child Nutrition and Water Access
- Celiac Disease Research and Management
- Advanced Wireless Communication Techniques
- Magnetic Field Sensors Techniques
- Atherosclerosis and Cardiovascular Diseases
- Advanced Wireless Network Optimization
Hospital Italiano de Buenos Aires
2021-2024
University of Parma
2013-2022
Poste Italiane (Italy)
2014
Politecnico di Milano
2008
Rheumatoid arthritis (RA) is associated with accelerated atherosclerosis. The reduction in cardiovascular risk that induced by methotrexate (MTX) and anti-tumor necrosis factor α agents RA considered secondary to their anti-inflammatory action, but effects on serum lipoprotein function foam cell formation are unknown. reduced capacity of high-density (HDL) promote cholesterol efflux the increased cholesterol-loading (CLC) demonstrated may contribute development. aim this study was...
Type 1 diabetes (T1D) results from a breakdown in immunological tolerance, with pivotal involvement of antigen-presenting cells. In this context, antigen-specific immunotherapies have been developed to arrest autoimmunity, such as phosphatidylserine (PS)-liposomes. However, the role certain cells immunotherapy, particularly human macrophages (Mφ) T1D remains elusive. The aim study was determine Mφ immune tolerance and T1D. To that end, we evaluated ability capture apoptotic-body mimicking...
Abstract A direct aminocatalytic synthesis has been developed for the chemo‐, regio‐, diastereo‐, and enantioselective construction of densely substituted polycyclic carbaldehydes containing fused cyclohexadiene rings. The chemistry utilizes, first time, remotely enolizable π‐extended allylidenemalononitriles as electron‐rich 1,3‐diene precursors in a eliminative [4+2] cycloaddition with both aromatic aliphatic α,β‐unsaturated aldehydes. generality process is demonstrated by approaching...
Lipid metabolism derangement contributes to increased cardiovascular risk in Rheumatoid Arthritis (RA). It is still debated whether and how tocilizumab, an interleukin-6 receptor inhibitor used active RA, impacts risk. We studied the effect of tocilizumab on regulation macrophage cholesterol homeostasis, measuring patient serum ability respectively load (cholesterol loading capacity, CLC) discharge efflux CEC) cells with cholesterol. Patients RA (n = 8) were before after 4 12 weeks...
Abstract A direct aminocatalytic synthesis has been developed for the chemo‐, regio‐, diastereo‐, and enantioselective construction of densely substituted polycyclic carbaldehydes containing fused cyclohexadiene rings. The chemistry utilizes, first time, remotely enolizable π‐extended allylidenemalononitriles as electron‐rich 1,3‐diene precursors in a eliminative [4+2] cycloaddition with both aromatic aliphatic α,β‐unsaturated aldehydes. generality process is demonstrated by approaching...
Despite the efficacy in reducing acute rejection events organ transplanted subjects, long term therapy with cyclosporine A is associated increased atherosclerotic cardiovascular morbidity. We studied whether this drug affects antiatherogenic process of reverse cholesterol transport from macrophages vivo. Cyclosporine 50 mg/kg/d was administered to C57BL/6 mice by subcutaneous injection for 14 days. Macrophage assessed following [3H]-cholesterol mobilization pre-labeled intraperitoneally...
IEEE 802.16 is an emerging technology for broadband cellular wireless communications. In the context of high capacity systems mobile terminals, implementation issues like channel estimation become more challenging because sparsity pilots grid (w.r.t. coherence bandwidth) and time varying nature channel. This paper proposes a novel algorithm that characterized by good trade-off between complexity performance. The algorithm, suitable pilot-aided OFDM transmission, applied here to 802.16e...
Spondyloarthropathies (SpA) are associated with increased cardiovascular risk. Among possible mechanisms is the dysfunction of serum lipoproteins in regulating cell cholesterol homeostasis. Cholesterol efflux capacity (CEC)-the atheroprotective ability HDL (high density lipoproteins) to accept from macrophages-might predict disease independently HDL-cholesterol levels. We aimed at evaluating modifications CEC and atherogenic loading (CLC) psoriatic arthritis (PsA) ankylosing spondylitis (AS)...
Revisión sistemática Las intervenciones que promueven el acceso a agua segura, saneamiento e higiene disminuyen la mortalidad infantil en países de bajos y medianos ingresosInterventions that promote access to safe water, sanitation and hygiene reduce child mortality in low-and middle-income countries
It has been well established that moderate alcohol consumption inversely correlates with cardiovascular morbidity and mortality, whereas binge drinking increases disease risk. The aim of this study was to assess in vivo the impact different patterns on reverse cholesterol transport (RCT); atheroprotective process leading removal excess from body. RCT measured a standardized, radioisotope-based technique three groups atherosclerosis-prone apolipoprotein E knock out mice: Placebo group,...
The paper will stress the role of wireless current sensors in converting assessed factories and buildings, endowed with a reduced metering equipment, to Industrial Internet-of-Things (IIoT) paradigm, by renovating increasing at cost installed devices architecture. In this way great number algorithms application are made available, from cloud edge computing, improve general efficiency plant factory. An experimental setup, under test, report significant results.
The evolution of microchips and embedded technologies those related to the mobile world has led growth proliferation devices systems for electronic payment used by end users buy products or services. Over last few years there been a tendency use these provide way benefit services that are accessories (e.g. Value Added Services - VAS) can be before after transaction takes place. heterogeneity users' instruments, linked acceptance service platforms, also makes life harder new providers...
<h3>Background</h3> RA is associated with accelerated atherosclerosis. HDL in have reduced capacity to promote cell cholesterol efflux (CEC) while LDL increased loading on macrophages (CLC). Inflammation and immune disturbances are among the mechanisms proposed. Anti-TNFa agents appear reduce cardiovascular risk RA, but their effects serum lipid profile variable. <h3>Objectives</h3> We studied modifications of lipoprotein function respect trafficking after adalimumab therapy RA....
El uso de una herramienta apoyo para la desprescripción no redujo las reacciones adversas a medicamentos en adultos mayoresThe use of decision support tool did not reduce adverse drug reactions in older adults