A5011598498- Luminescence and Fluorescent Materials
- Porphyrin and Phthalocyanine Chemistry
- Synthesis and Reactivity of Heterocycles
- Nanoplatforms for cancer theranostics
- Fullerene Chemistry and Applications
- Dendrimers and Hyperbranched Polymers
- Photoacoustic and Ultrasonic Imaging
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced Chemical Physics Studies
- Manufacturing Process and Optimization
- Ultrasound and Cavitation Phenomena
- Spectroscopy and Quantum Chemical Studies
- BIM and Construction Integration
- Seismic Imaging and Inversion Techniques
- Synthesis and Biological Evaluation
- Advanced Nanomaterials in Catalysis
- Diamond and Carbon-based Materials Research
- Photochemistry and Electron Transfer Studies
- Graphene research and applications
- Adsorption and biosorption for pollutant removal
- Environmental Impact and Sustainability
- Cancer therapeutics and mechanisms
- Underwater Acoustics Research
- Electrostatics and Colloid Interactions
- Protein Interaction Studies and Fluorescence Analysis
University of Mississippi
2018-2024
University of Oxford
2022
The main objective of a series our researches is to develop novel acoustic-based method for activation biochar. This study investigates the capability biochar in adsorbing Ni(II) as hazardous contaminant and aims at enhancing its adsorption capacity by addition extra nitrogen most probably phosphorous oxygen containing sites using an ultrasono-chemical modification mechanism. To reach this objective, physically modified low-frequency ultrasound waves (USB) was chemically treated phosphoric...
Herein, we focus on the design, synthesis, and characterization of thienothiadiazole (TTD)-based near-infrared II (NIR-II) theranostic fluorophores their nanoparticles.
Gold nanoparticles (AuNPs) are commonly used in cancer research due to their unique physical and optical properties. However, current AuNP synthesis methods often involve cytotoxic cationic surfactants like cetyltrimethyl ammonium bromide (CTAB). Tedious CTAB replacement methodologies have been increase the biocompatibility, further increasing complexity of synthesizing biocompatible AuNPs limiting biomedical applications. To address this issue, we explore cholinium decanoate (CADA) ionic...
Shortwave infrared (SWIR)-emitting small molecules are desirable for biological imaging applications. In this study, four novel pentamethine indolizine cyanine dyes were synthesized with N,N-dimethylaniline-based substituents on the periphery at varied substitution sites. The studied via computational chemistry and optical spectroscopy both in solution when encapsulated. Dramatic spectral shifts absorption emission spectrum wavelengths added donor groups observed. Significant an emissive...
Shortwave infrared (SWIR) emission has great potential for deep-tissue
Due to its abundance in blood, a great deal of research has been undertaken develop efficient biosensors for serum albumin and provide insight into the interactions that take place between these biosensing molecules protein. Near-infrared (NIR, >700 nm) organic dyes have shown be effective albumin, but their effectiveness is diminished whole blood. Herein, it an NIR sulfonate indolizine-donor-based squaraine dye, SO3SQ, can strengthened as biosensor through addition biocompatible ionic...
Abstract Small organic molecules absorbing and emitting in the shortwave infrared (SWIR, 1000–2000 nm) region are desirable for biological imaging applications due to low auto‐fluorescence, reduce photon scattering, good tissue penetration depth of photons which allows vivo with high resolution sensitivity. Si‐substituted xanthene‐based fluorophores indolizine donors have demonstrated some longest wavelengths absorption emission from dyes. This work seeks compare an heterocyclic nitrogen...
Small molecular organic fluorophores have garnered significant interest because of their indispensable use in fluorescence imaging (FI) and optoelectronic devices. Herein, we designed triphenylamine (TPA)-capped donor–acceptor–donor (D–A–D)-based having a variation at the heterocyclic donor (D) units, 3,4-ethylenedioxythiophene (EDOT), furan (FURAN), thiophene (THIO), 1-methyl-1H-pyrrole (MePyr), with isoindigo as core electron acceptor (A) unit. Synthesis these (II-X-TPA) resulted four...
Fluorescent organic dyes that absorb and emit in the near-infrared (NIR, 700–1000 nm) shortwave infrared (SWIR, 1000–1700 regions have potential to produce noninvasive high-contrast biological images videos. BODIPY are well known for their high quantum yields visible energy region. To tune these chromophores NIR region, fused nitrogen-based heterocyclic indolizine donors were added a scaffold. The synthesized via microwave-assisted Knoevenagel condensation with aldehydes. non-protonated...
Abstract Changes in the viscosity of intracellular microenvironments may indicate onset diseases like diabetes, blood‐based illnesses, hypertension, and Alzheimer's. To date, monitoring changes environment remains a challenge with prior work focusing primarily on visible light‐absorbing sensing fluorophores. Herein, series near‐infrared (NIR, 700–1000 nm) absorbing emitting indolizine squaraine fluorophores ( 1PhSQ , 2PhSQ SO 3 SQ 1DMASQ 7DMASQ 1,7DMASQ ) are synthesized studied for NIR...
The challenges faced with current fluorescence imaging agents have motivated us to study two nanostructures based on a hydrophobic dye, 6 H -pyrrolo[3,2- b :4,5- ’]bis [1,4]benzothiazine (TRPZ). TRPZ is heteroacene rigid, pi-conjugated structure, multiple reactive sites, and unique spectroscopic properties. Here we coupled tert-butyl carbamate (BOC) protected 2,2-bis(hydroxymethyl)propanoic acid (bisMPA) dendron via azide-alkyne Huisgen cycloaddition. Deprotection of the amine groups...
The biological effects of acoustic cavitation are mediated by a range phenomena associated with different types bubble activity, e.g., micro-streaming, micro-jetting, and shockwave generation. emissions generated also correlated to dynamics. Hence, monitoring these during ultrasound therapy is desirable, maximise treatment safety efficacy. precise relationship between the spectral content dynamics is, however, less well understood. aim this study was use simultaneous ultra-high-speed optical...
Guest-host Raman under liquid nitrogen spectroscopy (GHRUNS) is introduced whereby solid-state guest molecules are isolated inside cage-like host environments for the facile acquisition of their spectra. This convenient method features reduced fluorescence, analysis populations in ground states, and increased signal to noise ratios. Samples also preserved through reduction thermal degradation oxidation. To demonstrate benefits this new method, spectra ubiquitous molecule C60 a cage water ice...
Abstract The front cover artwork is provided by Dr. Nathan Hammer's group at the University of Mississippi. image shows encapsulation C 60 “iceberg” water, analogous to methodology authors implement acquire enhanced Raman spectra fullerene. Read full text Research Article 10.1002/cphc.202200309 .
Since the development of original passive acoustic mapping (PAM) algorithm for cavitation imaging in 2008, which employed a conventional beamformer adapted from seismology (time exposure acoustics), sequential algorithmic improvements have sought to enhance spatial resolution, reduce computation time and enable increasingly setup-independent reporting activity. These enhancements included use frequency-domain rather than time-domain implementations improve computational efficiency,...