A5070323349- Reconstructive Surgery and Microvascular Techniques
- Head and Neck Cancer Studies
- Reconstructive Facial Surgery Techniques
- Nerve Injury and Rehabilitation
- Oral and Maxillofacial Pathology
- Facial Nerve Paralysis Treatment and Research
- Nutrition and Health in Aging
- Oral health in cancer treatment
- Head and Neck Surgical Oncology
- Vascular Malformations and Hemangiomas
- Bone Tumor Diagnosis and Treatments
- Surgical site infection prevention
- Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Breast Implant and Reconstruction
- Wound Healing and Treatments
- Facial Trauma and Fracture Management
- Sarcoma Diagnosis and Treatment
- Diabetic Foot Ulcer Assessment and Management
- Streptococcal Infections and Treatments
- Ear and Head Tumors
- Intensive Care Unit Cognitive Disorders
- Orthopedic Surgery and Rehabilitation
- Temporomandibular Joint Disorders
- Cancer and Skin Lesions
Gunma University
2016-2025
National Hospital Organization Takasaki Medical Center
2023-2024
Hirosaki University
2023
Suzuki (Japan)
2021-2022
Weatherford College
2021-2022
Shimizu (Japan)
2021
Gunma University Hospital
2015-2018
Kobe University
2009-2016
May Institute
2016
L-type amino acid transporter 1 (LAT1), also referred to as SLC7A5, is believed regulate tumor metabolism and be associated with proliferation. In invasive breast cancer, we clinicopathologically investigated the utility of LAT1 expression. expression was evaluated via immunohistochemistry analyses in 250 cancer patients undergoing long-term follow-up. We assessed relationships between patient outcomes clinicopathological factors. Breast cancer-specific survival stratified by assessed. Human...
Background: Hospital-acquired pressure ulcers (HAPU) are a major challenge in healthcare settings, especially vulnerable populations such as patients with COVID-19. The aim of this study is to examine the association COVID-19 infection occurrence HAPU, goal enhancing care protocols and reducing HAPU incidence at-risk populations. Methods: A retrospective analysis was conducted for 8,158 hospitalized aged 20 years older who were treated from April 2022 March 2023. included COVID-19-positive...
Background Diabetic foot ulcer (DFU) is a severe complication of diabetes. Nutritional deficiencies, including poor nutritional status reflected by high CONUT score and low serum zinc have been implicated in the severity wound healing failure DFU. However, association between these factors DFU remains unclear. Methods A retrospective cohort study was performed 319 patients categorized into three groups: healthy controls (HC, n = 213), with diabetes without (DM, 67), (DFU, 39). Demographic,...
Use of a vascularized free fibula flap has become preferred method mandible reconstruction after oncologic surgical ablation. Despite its many advantages, the low vertical height graft is potential drawback and severe long-term atrophy fibular bones may cause stress fracture disadvantageous for osseointegrated dental implants facial contours. Therefore, it important to investigate degree resorption based on factors related over time. The influence aspects intraoperative procedure, such as...
Abstract Background Sarcopenia is a disease in which skeletal muscle mass (SMM) and function are progressively lost. Here, we investigate surgical site infection (SSI) as of SMM patients who underwent free flap reconstruction for defect caused by oral cancer resection. Methods A nonrandomized, retrospective group 122 treated with after resection was enrolled the study. All subjects also preoperative abdominal‐lumbar computed tomography (CT). Cross‐sectional areas (cm 2 ) muscles L3 region...
Postoperative delirium (POD) is a major risk factor for an extended hospital stay and higher costs, associated with increased mortality. The incidence of POD high in free flap procedures, may also be loss complications. Sarcopenia condition characterized by skeletal muscle mass (SMM) depletion decrease power or physical activity. aim this study was to investigate factors postoperative (POD), including SMM, 122 patients undergoing repair after oral cancer resection. All underwent preoperative...
Necrotizing fasciitis (NF) is a severe soft tissue infection that can spread rapidly throughout the body, often resulting in fatal outcomes. Negative pressure wound therapy (NPWT) enhances healing by applying local negative pressure, and its effectiveness managing NF has been documented. However, NPWT creates semi-closed environment at site, posing risk of infection. Continuous antibiotic perfusion (CLAP) an innovative approach uses localized infusion to deliver high concentrations...
The pectoralis major musculocutaneous (PMMC) flap was once considered the workhorse for head and neck reconstruction; however, because of proliferation free tissue transfer, it has rightly taken on a secondary role. Nevertheless, in certain reconstructions, PMMC remains last-line treatment only salvage option do-or-die scenarios. conventional harvesting method cuts lateral thoracic artery all intercostals branches from internal mammary vessel to avoid compromising pedicle length....
Tumor-infiltrating lymphocytes (TILs) are a significant prognostic factor in triple-negative breast cancer. However, the clinicopathological significance of TILs estrogen receptor (ER)-positive and human epidermal growth 2 (HER2)-negative cancer remains unclear. The purpose present study was to evaluate role prognosis ER-positive HER2-negative A total 65 consecutive patients with were examined. stromal tissue (str-TILs) graded using International Working Group criteria. association between...
Abstract Background Immediate breast reconstruction with skin-sparing (SSM) or nipple-sparing mastectomy (NSM) has become a common procedure. In this study, we evaluated the distance between tumor and skin in series of patients undergoing IBR as it relates to oncologic safety, namely, incidence recurrence. Methods The dermis, rather than outer layer skin, was key parameter our preoperative ultrasound measurements. Our data set comprised cases 171 181 breasts cancer that had undergone...
This study aimed to determine whether elective neck dissection can help improve outcomes in early-stage tongue and floor squamous cell carcinoma (SCC) by statistically analysing the relationship between information obtained from biopsy specimens incidence prognosis of cervical lymph node metastasis (CLM).
Lipoma is a benign tumor that often arises in the craniomaxillofacial region. Osteolipoma containing bone tissue very rare and developmental mechanism unclear. Mesenchymal stem cells adipose have potential to differentiate into fat, bone, cartilage, vascular components may be involved development of osteolipoma, which tissues coexist. We encountered patient with osteolipoma arose glabella. describe case results an investigation presence lipomas mesenchymal differentiation similar normal...
Ameloblastic carcinoma is a very rare malignant odontogenic tumor. We report case of secondary-type ameloblastic that extended transversally over almost half the side face. Malignant transformation and identification region in large tumor were achieved using L-3-[18F]fluoro-α-methyltyrosine (FAMT)–positron emission tomography (PET); FAMT transported into cancer cells by L-type amino acid transporter 1 shows high specificity for tumors. The determined microscopic evaluation resected samples...
The objectives of surgical treatment for microstomia due to cicatricial contracture after burn are obtain sufficient oral aperture, while maintaining sphincter function the orbicularis oris muscle, and secure favorable eating conversation in addition good health.The lips mouth have a free border, which has been enlarged by operation, tends be reduced, because actions muscle. When muscle is resected, putting priority on aperture prevention redevelopment contracture, often damaged. With...
Oro-cervical necrotizing fasciitis (OCNF) treatment requires early surgical debridement and opening of the wound, therefore, diagnosis is very important. The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score based on blood test data has recently been proposed as an auxiliary diagnostic tool. However, in some cases, it difficult to diagnose OCNF. We performed a pooled analysis patients with OCNF at Gunma University Hospital literature goal designing new tool by adding...