A5053814099- Micro and Nano Robotics
- Particle Dynamics in Fluid Flows
- Elasticity and Material Modeling
- Cardiovascular Function and Risk Factors
- Lower Extremity Biomechanics and Pathologies
- Fluid Dynamics and Turbulent Flows
- Pulmonary Hypertension Research and Treatments
- Cardiovascular Health and Disease Prevention
- Lattice Boltzmann Simulation Studies
- Gaussian Processes and Bayesian Inference
- Coronary Interventions and Diagnostics
- Microfluidic and Bio-sensing Technologies
- Cellular Mechanics and Interactions
- Advanced Thermodynamics and Statistical Mechanics
- Total Knee Arthroplasty Outcomes
- Mathematical Biology Tumor Growth
- Cardiac Imaging and Diagnostics
- Corneal surgery and disorders
- Hemodynamic Monitoring and Therapy
- Glaucoma and retinal disorders
- Skin and Cellular Biology Research
- Evolution and Genetic Dynamics
- Advanced MRI Techniques and Applications
- Aortic aneurysm repair treatments
- Nonlinear Dynamics and Pattern Formation
University of Glasgow
2015-2024
Royal United Hospital Bath NHS Trust
2024
Nicolaus Copernicus University
2020
Collegium Medicum in Bydgoszcz
2020
Goodyear (United States)
2011
Dalhousie University
2009
Robarts Clinical Trials
2005-2007
Western University
2005-2007
Kingston General Hospital
2006
Queen's University
2003-2006
'Bioconvection' is the name given to pattern-forming convective motions set up in suspensions of swimming micro-organisms. 'Gyrotaxis' describes way guided through a balance between physical torques generated by viscous drag and gravity operating on an asymmetric distribution mass within organism. When organisms are heavier towards rear, gyrotaxis turns them so that they swim regions most rapid downflow. The presence means bioconvective instability can develop from initially uniform...
Bioconvection patterns are usually observed in the laboratory shallow suspensions of randomly, but on average upwardly, swimming micro-organisms which a little denser than water, have also been found situ micropatches zooplankton [Kils (1993), 1993. Bull. Mar. Sci. 53, 160–169]. The mechanism upswimming differs between bottom-heavy algae and oxytactic bacteria. Rational continuum models formulated analysed each these cases for low cell volume fraction. These will be described, as new...
The effect of gyrotaxis on the linear stability a suspension swimming, negatively buoyant micro-organisms is examined for layer finite depth. In steady basic state there no bulk fluid motion, and upwards swimming cells balanced by diffusion resulting from randomness in their shape, orientation behaviour. This leads to density stratification with denser top. theory based continuum model Pedley, Hill & Kessler (1988), employs both asymptotic numerical analysis. characterized five...
Background: Patellofemoral pain syndrome is a prevalent condition in young people. While it widely believed that abnormal patellar tracking plays role the development of patellofemoral syndrome, this link has not been established. The purpose cross-sectional case-control study was to test hypothesis patterns spin, tilt, and lateral translation make possible distinguish individuals with clinical evidence malalignment from those no knee problems. Methods: Three-dimensional joint kinematics one...
Microvascular angina is caused by cardiac small vessel disease, and dysregulation of the endothelin system implicated. The minor G allele non-coding single nucleotide polymorphism (SNP) rs9349379 enhances expression 1 gene in human vascular cells, increasing circulating concentrations ET-1. prevalence this higher patients with ischemic heart disease. Zibotentan a potent, selective inhibitor ET
Using the continuum model of Pedley, Hill & Kessler (1988) for bioconvection in a suspension swimming, gyrotactic micro-organisms, we investigate existence and stability two-dimensional plume tall, narrow chambers with stress-free sidewalls. The system is governed by Navier–Stokes equations an incompressible fluid coupled micro-organism conservation equation. These are solved numerically using conservative finite-difference scheme. In sufficiently deep chambers, always unstable to both...
Bioconvection occurs as the result of collective behaviour many micro-organisms swimming in a fluid and is realised patterns similar to those thermal convection which occur when layer water heated from below. A methodology developed record bioconvection that are formed by aqueous cultures single-celled alga Chlamydomonas nivalis. The analysis used quantify function cell concentration, suspension depth time described experimental results presented.
To gain insight into cardio-arterial interactions, a coupled left ventricle-systemic artery (LV-SA) model is developed that incorporates three-dimensional finite-strain ventricle (LV), and physiologically-based one-dimensional for the systemic arteries (SA). The coupling of LV SA achieved by matching pressure flow rate at aortic root, i.e. feeds back as boundary condition to model, from used input model. governing equations system are solved using combined immersed-boundary finite-element...
We have analyzed the initiation of pattern formation in a layer finite depth for Pedley and Kessler’s new model [J. Fluid Mech. 212, 155 (1990)] bioconvection. This is first analysis bioconvection realistic geometry using that deals with random swimming rational manner. considered effects distribution speeds, which has not previously received attention theoretical papers find it important calculating diffusivity. Our predictions initial wavelengths are reasonably close to observed ones but...
The theory of generalized Taylor dispersion for suspensions Brownian particles is developed to study the gyrotactic swimming micro-organisms in a linear shear flow. Such creatures are bottom-heavy and experience gravitational torque which acts right them when they tipped away from vertical. They also suffer net viscous presence local vorticity field. orientation cells intrinsically random but balance two torques results bias toward preferred direction. sufficiently large that motion...
In this paper we develop a new generic model for phototaxis in suspension of microscopic swimming algae. Phototaxis is directed response dependent upon the light conditions sensed by microorganisms. Positive consists motions toward source illumination and negative motion away from it. The also incorporates effect shading whereby microorganisms nearer absorb scatter before it reaches those further away. This then used to analyse linear stability phototactic algae, uniformly illuminated above,...
MEPS Marine Ecology Progress Series Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsTheme Sections 279:215-224 (2004) - doi:10.3354/meps279215 Random walk models for movement and recruitment of reef fish larvae E. A. Codling1,4, N. Hill2,*, J. W. Pitchford3, S. D. Simpson3,5 1Department Applied Mathematics, University Leeds, Leeds LS2 9JT, UK 2Department Glasgow, Glasgow G12 8QQ, 3Department Biology, York,...
The distribution of collagen fibres plays a significant role in the mechanical behaviour artery walls. Experimental data show that most wall layers there are two (or more) in-plane symmetrically disposed families fibres. However, recent investigation revealed some have only one preferred fibre direction, notably medial layer human common iliac arteries. This paper aims to provide possible explanation for this intriguing phenomenon. An invariant-based constitutive model is utilized...
This paper studies dissection propagation subject to internal pressure in a residually-stressed two-layer arterial model. The artery is assumed be infinitely long, and the resultant plane strain problem solved using extended finite element method. layers are modelled anisotropic hyperelastic Holzapfel–Gasser–Ogden model, tissue damage due tear described linear cohesive traction–separation law. Residual stress wall determined by an opening angle $$\alpha $$ stress-free configuration. An...
This study uses Bayesian inference to quantify the uncertainty of model parameters and haemodynamic predictions in a one-dimensional pulmonary circulation based on an integration mouse micro-computed tomography imaging data. We emphasize often neglected, though important source uncertainty: mathematical form due discrepancy between reality, measurements wrong noise (jointly called ‘model mismatch’). demonstrate that minimizing mean squared error measured predicted data (the conventional...
Using the continuum model of Pedley et al. [J. Fluid Mech. 195, 223 (1988)] for bioconvection in a suspension swimming, gyrotactic micro-organisms, existence and stability periodic arrays two-dimensional plumes deep chambers are investigated. The system is governed by Navier–Stokes equations an incompressible fluid coupled with micro-organism conservation equation. These solved numerically using conservative finite-difference scheme. In sufficiently chambers, sometimes unstable to varicose...