A5102979022- Inflammatory Bowel Disease
- Advancements in Battery Materials
- Microscopic Colitis
- Supercapacitor Materials and Fabrication
- Metal-Organic Frameworks: Synthesis and Applications
- Advanced Battery Materials and Technologies
- Cancer Immunotherapy and Biomarkers
- Lignin and Wood Chemistry
- Viral gastroenteritis research and epidemiology
- Microwave Engineering and Waveguides
- Lung Cancer Research Studies
- Nanoplatforms for cancer theranostics
- Pancreatic and Hepatic Oncology Research
- Electrospun Nanofibers in Biomedical Applications
- Ultrasound and Hyperthermia Applications
- Tissue Engineering and Regenerative Medicine
- Amphibian and Reptile Biology
- Photoacoustic and Ultrasonic Imaging
- Oxidative Organic Chemistry Reactions
- Peptidase Inhibition and Analysis
- 3D Printing in Biomedical Research
- Spatial and Panel Data Analysis
- Systemic Lupus Erythematosus Research
- Land Use and Ecosystem Services
- Advanced Antenna and Metasurface Technologies
The First Affiliated Hospital, Sun Yat-sen University
2024-2025
Zhongshan Hospital
2024-2025
Fudan University
2024-2025
Sun Yat-sen University
2024-2025
Nanjing University
2023-2025
Nanjing General Hospital of Nanjing Military Command
2024-2025
Shanghai Institute of Hematology
2020-2025
Wuhan University
2022-2025
Renmin Hospital of Wuhan University
2022-2025
Harbin Medical University
2025
Breast cancer remains the leading cause of cancer-related deaths among women worldwide, necessitating more effective treatment strategies. Chemotherapy combined with immunotherapy is first-line for breast cancer, but it still suffers from limited therapeutic efficiency and serious side effects, which are usually due to poor delivery efficiency, drug resistance tumor cells, immunosuppressive microenvironment. This study explores development ultrasound-responsive nanobubbles (Ce6/PTX Nbs)...
A novel dual-band coplanar waveguide (CPW)-fed slot antenna with a C-shaped grounded strip is proposed for dual-sense circularly polarized radiation. The circular polarization in the lower band achieved by slots loaded two opposite corners, and C-shape can offer current path upper band. rectangular tuning stub protruded into from signal of CPW used to obtain good impedance matching over whole frequency Axial-ratio (AR) bandwidth be significantly enhanced through horizontal length strip. has...
A strategy is proposed for a surface-modified LiCoO<sub>2</sub> heterostructure by <italic>in situ</italic> MOF-derived carbon coating to achieve distinguished performance elevated-voltage lithium storage.
Si-Miao-San (SMS) is a well-known traditional Chinese medicine. This study aims to evaluate the anti-inflammatory effects of SMS on gouty arthritis and its potential mechanism action.
Due to the increasingly serious energy consumption and demand worldwide, development of advanced, flexible, versatile advanced batteries related materials has become an important research topic in modern world. Copper-based metal–organic frameworks (Cu-MOFs) have large specific surface areas, high porosities, adjustable structures, simple preparation methods, low cost. In recent years, on chemical composition, structure, application Cu-MOFs their derivatives undergone continuous changes...
A comprehensive strategy for the morphological control of octahedral and spindle Fe-based metal-organic frameworks (Fe-MOFs) via microwave-assisted adjustment is proposed in this research. Afterward, situ copyrolysis under N2 atmosphere contributes to fabrication two shape-maintained FeF3·0.33H2O nanostructures (named O-FeF3·0.33H2O S-FeF3·0.33H2O, respectively) with confined hierarchical porosity graphitized carbon skeleton. The lithium storage performances MOF-derived S-FeF3·0.33H2O...
Abstract Objectives Since a reliable model for predicting infliximab (IFX) benefits in bio-naïve Crohn’s disease (CD) is still lacking, we constructed magnetic resonance enterography (MRE)-based to predict the risk of loss response IFX patients with CD. Methods This retrospective multicenter study enrolled 188 CD who underwent MRE before therapy. Therapeutic outcomes were determined based on clinical symptoms and endoscopic findings within 52 weeks. The areas bowel wall segmentation decided...
Background: Prostate cancer (PCa) poses a significant global health threaten. Immunotherapy has emerged as novel strategy to augment the inhibition of tumor proliferation. However, sole use anti-PD-L1 Ab for PCa not yielded improvements, mirroring outcomes observed in other types. Methods: This study employed thin film hydration method develop lipid nanobubbles (NBs) encapsulating chlorin e6 (Ce6) and (Ce6@aPD-L1 NBs). Our experimental approach included cellular assays mouse immunization,...
Abstract Efficient thrombolysis in time is crucial for prognostic improvement of patients with acute arterial thromboembolic disease, while limitations and complications still exist conventional thrombolytic treatment methods. Herein, our study sought to investigate a novel dual-mode strategy that integrated ultrasound (US) near-infrared light (NIR) establishment hollow mesoporous silica nanoprobe (HMSN) which contains Arginine-glycine-aspartate (RGD) peptide (thrombus targeting),...
<title>Abstract</title> This study explored the potential of a low-protein diet (LPD) to modulate gut microbiota, focusing on pancreatic ductal adenocarcinoma (PDAC) progression and response immunotherapy. A 25% reduction in dietary protein intake attenuated PDAC development, drove immune activation tumor microenvironment (TME) boosted immunostimulatory tumor-associated macrophages (TAMs) phenotype. We found depletion microbiota compromised anti-tumor effect LPD. Specifically, significant...
There is growing evidence that individuals with cardiovascular disease (CVD) are more likely to develop depression. The timing of food intake can significantly alter the body's circadian rhythm and affect occurrence Currently, it unknown whether how energy or macronutrient times associated depression in adults CVD. To evaluate dietary (across three meals) associations CVD a nationally representative sample. study population consisted 3,490 U.S. (including 554 depression) from National Health...
The benefits of continuing immunotherapy beyond disease progression in advanced non-small cell lung cancer (NSCLC) and small (SCLC) remain uncertain, along with the specific patient subgroups that may gain most from this approach. This retrospective study aims to evaluate efficacy approach identify target populations likely benefit. We collected data patients NSCLC SCLC who experienced following initial immune checkpoint inhibitor (ICI) treatment January 2020 December 2023. Patients were...
Background/Objectives: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with poor early detection rates owing to the limited sensitivity and specificity of current biomarker CA19-9. Gut microbiota dysbiosis plays key role in PDAC pathogenesis. This study aimed evaluate noninvasive approach we developed, combining metagenome-derived microbial signatures CA19-9, improve detection. Methods: included 50 treatment-naïve patients their matched controls. Fecal samples were...
p-benzyloxyl phenol (PBP), as a lignin model compound, was electrochemically degraded in [BMIM]BF4 ionic liquid (IL) using an oxygen reduction reaction (ORR) cathode. The utilization of this kind aprotic IL made it possible to identify which reactive species (ROS) played important role the electrochemical depolymerization lignin. Electrochemical study confirmed that superoxide radical (·O2−), one-electron reductive product dioxygen, is main resultant ORR [BMIM]BF4. However, generated ·O2−...
The prediction of the loss response (LOR) to infliximab (IFX) is crucial for optimizing treatment strategies and shifting biologics. However, a secondary LOR difficult predict by endoscopy due intestinal stricture, perforation, fistulas. This study aimed develop validate radiomic nomogram IFX in patients with Crohn's disease (CD).A total 186 biologic-naive diagnosed CD between September 2016 June 2019 were enrolled. Secondary was determined during week 54. Computed tomography enterography...
In this work, a new design of zeolitic imidazolate framework-derived CoF2/Fe2O3 hybrid structure is reported via simple copyrolysis strategy. The in situ generated C/N doped framework effectively enhances its own conductivity and offers more Li+-active insertion sites. distinctive nanoscale not only provides adequate space to accommodate volume changes, but also promotes electrolyte penetration into the electrode, leading higher utilization active materials faster ion/electron transfer...