- Sinusitis and nasal conditions
- Pleural and Pulmonary Diseases
- Lung Cancer Diagnosis and Treatment
- Pulmonary Hypertension Research and Treatments
- Microbial Natural Products and Biosynthesis
- Fungal Biology and Applications
- Biliary and Gastrointestinal Fistulas
- Gallbladder and Bile Duct Disorders
- Respiratory Support and Mechanisms
- Gastric Cancer Management and Outcomes
- Endometriosis Research and Treatment
- Metastasis and carcinoma case studies
- Amoebic Infections and Treatments
- Omental and Epiploic Conditions
- Cleft Lip and Palate Research
- Nasal Surgery and Airway Studies
- Cardiac Structural Anomalies and Repair
- Cystic Fibrosis Research Advances
- Cardiac, Anesthesia and Surgical Outcomes
- Pericarditis and Cardiac Tamponade
- Intraperitoneal and Appendiceal Malignancies
- Gastrointestinal disorders and treatments
- Esophageal and GI Pathology
- Uterine Myomas and Treatments
- Head and Neck Surgical Oncology
Yokosuka Kyosai Hospital
2002-2023
Ehime Medical Center
2012-2022
National Hospital Organization
1997-2022
Suzuki (Japan)
2015-2016
Tohoku University
1992-2016
Naga Municipal Hospital
2014
Sendai Medical Center
2000-2013
Kitasato Institute Hospital
2005-2006
Jikei University School of Medicine
2002-2005
Handa City Hospital
2004
We evaluated the clinical efficacy of endonasal endoscopic sinus surgery (ESS) in patients with asthma associated chronic sinusitis. Twenty-one (13 men and 8 women) from 27 to 72 years old were enrolled this study. All had sinus-related symptoms for more than 3 months computed tomographic evidence paranasal opacification. Fifteen underwent bilateral ESS under local anesthesia, 6 other without controls. The preoperative postoperative periods assessed via a questionnaire. period prior was...
The mechanism of macrolide therapy in chronic sinusitis patients is unclear. authors studied the effect macrolides on interleukin (IL)-8 secretion from cultured human nasal epithelial cells. Epithelial cells harvested polyps with were primary-cultured, and secreted IL-8 culture media was measured by enzyme immunoassay. considerable amounts constitutively response to lipopolysaccharide. significantly inhibited 10(-5) M erythromycin, clarithromycin, roxithromycin, josamycin. 10(-6)...
BACKGROUND We aimed to investigate whether use of a survivin antisense fragment carried by an adenovirus vector (Ad.survivin-AS) could enhance the therapeutic efficacy chemotherapy for androgen-independent prostate cancer. METHODS used Ad.survivin-AS promote apoptosis through inhibition expression. Recombinant adenoviruses alone or in combination with chemotherapeutic agents were tested anti-cancer activity both vitro and vivo. RESULTS Infection strongly inhibited expression dose-...
To investigate the anatomical characteristics of nasal cavity and paranasal sinuses in relation to presence sinusitis patients with cleft lip palate.Retrospective survey.Tertiary care hospital.Forty-seven consecutive alveolus or without palate.The underwent computed tomographic scans maxilla, following parameters were evaluated: septal shift from midline, soft tissue density shadow maxillary sinus, cross-sectional area height floor sinus.The septum was convex side most unilateral clefts,...
A rare case of extramedullary plasmacytoma arising from the nasal septum with localized amyloid deposition is reported. 75-year-old woman presented a history post-nasal discharge and obstruction for several months. Endonasal endoscopic observation revealed presence mass her an extension to nasopharynx. No cervical lymph nodes were palpable. The biopsy specimen was diagnosed as (IgG, lambda-light chain type). Both serum myeloma-protein urine Bence-Jones protein negative. Bone marrow biopsy,...
Intestinal metaplasia, cancer and atypical epithelium of the gastric mucosa have been dyed by swallowing one capsule 100 mg methylene blue or directly spraying 0.5% under gastroscopio observation. The differential diagnosis these diseases from lesions was possible with endoscopic close-up appearances patterns. 1. metaplasia characterized fine foveolar (sulciolar) figures three types mucosal pattern (elevated, flat depressed). 2. Gastric revealed no but had irregularly dark dots in...
Pneumothorax associated with thoracic endometriosis (TE) generally occurs in women around 30 years old and it usually affects the right pleural cavity. We herein report two cases of TE left-sided pneumothorax young women. The prevalence younger patients may be underestimated if these are treated as spontaneous pneumothorax. occurring has not been reported to show laterality. TE-related or catamenial must therefore represent a different clinical entity from condition seen older patients.
Laminin is a major component of the extracellular matrix. The laminin γ1 chain least variant heterotrimeric assembly. gene (<i>LAMC1</i>) expression induced by several factors, including transforming growth factor-β (TGF-β). <i>LAMC1</i> promoter contains highly conserved transcriptional element, bcn-1. We screened cDNA libraries with yeast one-hybrid system to identify factors that are recognized bcn-1 motif. Using this strategy we isolated basic helix-loop-helix/leucine zipper (bHLHzip)...
Postcardiac injury syndrome (PCIS) occurs following a pericardial or myocardial injury. On the other hand, PCIS cardiac catheter intervention is rare and can be difficult to diagnose because of its delayed onset. A 24-year-old man underwent radiofrequency ablation (RFA) for paroxysmal atrial fibrillation suffered from general fatigue left-sided pleural effusion three months after procedure. His symptoms were effectively treated within month by administrating nonsteroidal anti-inflammatory...
Abstract Aim: Rhino-sinus mucosal involvement is well documented in untreated lepromatous leprosy, but less understood ex-leprosy patients (i.e. leprosy who have been treated and cured) with atrophic rhinitis. Materials methods: abnormalities were investigated 13 ex-lepromatous rhinitis, using interviews enquiring about sinonasal symptoms, nasal endoscopy, swab culture computed tomography. Endoscopic sinus surgery had performed three patients. The clinical course, tomography findings biopsy...
Acute appendicitis is a common disease that often requires emergency surgery. However, recently, not all cases are treated as an urgent operation, but surgery may be delayed to when medical resources abundant perform the operation safely. In such cases, preoperative antibiotics administered during waiting period. Though choice empiric, appropriate needed avoid Guidelines for of recognized international standards cannot applied in Asia due high rate extended-spectrum β-lactamase (ESBL)...
In the present study, ClC-3, one of voltage-dependent chloride channels, was identified in human nasal tissue. situ hybridization and immunohistochemical investigations demonstrated localization ClC-3 serous acini ductal portions submucosal glands, which are primary source secretion. Our data suggest that this channel contributes to secretion via transport. Its dysfunction might lead abnormal such pathological states as sinusitis.
症例は50歳,女性.2013年5月に右下腹部痛を自覚.近医にて大腸内視鏡検査を施行したところ上行結腸に輪状潰瘍を認め,腸結核が強く疑われた.6月下旬,急激な腹痛を主訴に当院に来院し,イレウスと診断され緊急入院・緊急手術となった.腸結核が疑われた上行結腸の狭窄部を含めた腸管切除術を施行した.切除標本で腸結核による狭窄部に椎茸がはまり込みイレウスを呈しているのが確認された. 腸結核の患者を診察する際は,常にイレウスの危険性を念頭に置いた早期治療が重要であり,さらには狭窄の強い症例では食事指導も必要と考えられた.
患者は59歳女性で,34歳時,左B領域の乳癌で乳房切除・腋窩リンパ節郭清を受けた.T1(1.0×0.8cm),N0,M0,病期I,充実腺管癌であった.乳癌術後13年,血中CEAが14ng/mlと上昇,CTで肝S4に大きさ3.5cmの多血性の腫瘤がみられた.乳癌肝転移の診断で肝左葉切除を施行した.摘出標本では5個の腫瘍がみられ,いずれも肝鎌状間膜の近傍に存在した(S4;2個,大きさ3.5cm,1.2cm,外側区域:3個,大きさ0.5-0.7cm).病理検索で肝腫瘍は乳癌の肝転移と診断され,ER(+),PgR(+)であった.術後CEF療法,エキセメスタン内服を行い,肝切除後12年再発なく健在である.原発乳癌の部位がB領域で,すべての肝転移巣が肝鎌状間膜近くに存在しており,転移経路として乳房から腹直筋を通って肝鎌状間膜近傍の肝臓へ至るリンパ路を介したリンパ行性肝転移の可能性が考えられた.
With the decreasing incidence of tuberculosis (TB), tuberculous abscess chest wall (TACW) is becoming rare. Pulmonary carcinoma coexisting with pulmonary TB has been reported in past, but reports accompanied TACW are scarce. We present first case a 66-year-old male carcinoma.