A5025197256- Catalytic Processes in Materials Science
- Metal-Organic Frameworks: Synthesis and Applications
- Efficiency Analysis Using DEA
- Sirtuins and Resveratrol in Medicine
- Nanomaterials for catalytic reactions
- Extracellular vesicles in disease
- Energy Efficiency and Management
- Catalysis and Oxidation Reactions
- Probabilistic and Robust Engineering Design
- Fibroblast Growth Factor Research
- Biometric Identification and Security
- Neuroinflammation and Neurodegeneration Mechanisms
- Epigenetics and DNA Methylation
- Covalent Organic Framework Applications
- Phase Change Materials Research
- Cancer Immunotherapy and Biomarkers
- Gas Sensing Nanomaterials and Sensors
- Advanced Photocatalysis Techniques
- Cell death mechanisms and regulation
- RNA Interference and Gene Delivery
- Inflammasome and immune disorders
- Adsorption and biosorption for pollutant removal
- Hippo pathway signaling and YAP/TAZ
- Luminescence Properties of Advanced Materials
- Energy, Environment, Economic Growth
Henan Polytechnic University
2024
State Key Laboratory of Oncogene and Related Genes
2017-2023
Shanghai Jiao Tong University
2017-2023
Renji Hospital
2023
Chinese Academy of Sciences
2022-2023
Changshu No.1 People's Hospital
2023
East China Jiaotong University
2018-2022
State Council of the People's Republic of China
2020
Air Force Medical University
2019
The University of Queensland
2017
The treatment for metastatic castration-resistant prostate cancer patients remains a great challenge in the clinic and continuously demands discoveries of new targets therapies. Here, we assess function therapeutic value SIRT6 cancer.
Abstract Immune Check-Point Inhibitors (ICIs) have shown remarkable promise in treating tumors, including non-small cell lung cancer (NSCLC). Nevertheless, the treatment response rate is low. Studies found that high expression of exosomal PD-L1 one reasons for low response. Therefore, this study focused on relationship between and clinical to immunotherapy NSCLC patients evaluate whether it could be used as a biomarker predict efficacy ICIs. In study, information blood samples 149 receiving...
Metal–organic framework (MOF)-based magnetic Pt catalyst Fe3O4@Pt@MIL-100(Fe) core–shell heterostructures were prepared through transforming Fe3O4 into MIL-100(Fe) in benzene-1,3,5-tricarboxylic acid solution along with encapsulating the nanoparticles successively adsorbed onto surface of nanosphere and continuously forming surfaces growing crystals. This method circumvented obstacles, controlling formation metal (MNPs) inside MOFs or regulating growth around MNPs, for preparing an MNP–MOF...
This study enhanced the dye adsorption capacity and efficiency over Fe3O4@MOFs series composite adsorbents through enhancing loading of MOFs. A multiple method was developed for controlling percentage MOFs in adsorbents, values which were calculated by analysis results thermogravimetric analysis, X-ray diffraction, Fourier transform infrared spectroscopy, photoelectron inductively coupled plasma mass spectrometry, Brunauer–Emmett–Teller, vibrating sample magnetometry measurements. Dye test...
• Knockdown of CDK5 down-regulates PD-L1 in lung adenocarcinoma and improves tumor immunity. Interference leads to ubiquitination degradation protein. TRIM21 mediates the process PD-L1. Combination disruption anti-PD-L1 therapy has a stronger effect on inhibiting formation, compared with knockdown alone. Although immunotherapy (anti-PD-1/PD-L1 antibodies) been approved for clinical treatment cancer, only small proportion patients respond monotherapy. Hence, understanding regulatory mechanism...
In response to stroke-induced injury, astrocytes can be activated and form a scar. Inflammation is an essential component for glial scar formation. Previous study has shown that adjudin, potential Sirt3 activator, could attenuate lipopolysaccharide (LPS)- neuroinflammation. To investigate the inhibitory effect mechanism of adjudin on astrocyte activation, we used transient middle cerebral artery occlusion (tMCAO) model with or without treatment in wild type (WT) knockout (KO) mice performed...
In order to enhance passenger willingness choose buses for commuting and reduce the operating costs tailpipe emissions of bus companies, a scheduling model is established. The aims minimize sum company, associated with loss passengers’ interest, cost emissions. It considers constraints such as maintaining an average load factor above 60%, ensuring departure interval greater than 5 min during non-peak hours less 30 peak hours, limiting maximum number allocated route. flow divided into nonpeak...
Summary Aims Sirt3 is one member of the NAD + ‐dependent protein deacetylase family and plays crucial roles in diverse aspects mammalian biological function. Then role on ischemia stroke unknown. Methods To examine effect ischemic stroke, we performed transient middle cerebral artery occlusion ( tMCAO ) adult male knockout KO wild‐type WT mice. Results The level infarct region decreased after stroke. In addition, found that mice showed worse neurobehavioral outcome compared with mice,...
The photoactive metal-organic frameworks (MOFs) were controllably coated on the surface plasmon resonance-excited Ag nanowires in a layer manner to adjust photocatalytic activity. influence of thickness MOF coating activity was investigated. A thicker not only facilitated photogenerated electron-hole separation efficiency but also provided larger Brunauer-Emmett-Teller area, thus enhancing This work new way MOF.
Single-layered, double-layered, and triple-layered Pt nanoparticles with a well-defined arrangement were encapsulated inside metal-organic frameworks (MOFs) to investigate the catalytic performance influenced by progressive increasing of MOFs; results show that activity Pt-MOF hybrid catalysts increases progressively MOFs. Progressive multiple-layered manner MOFs provides new route for designing well-organized noble metal enhanced activity.
Ectodermal mesenchymal stem cells (EMSCs) are harvested from the cell niche (nasal mucosa) with high therapeutic potential. To best of our knowledge, however, anti‑inflammatory properties these neural crest‑derived EMSCs have been rarely reported. The present study aimed to explore effects aerosolized EMSC‑Secretome (EMSC‑Sec) and clarify underlying mechanisms in treating acute lung injury (ALI). were isolated by adherent method identified immunofluorescence staining. EMSC‑Sec was collected...
Abstract Plant reoviruses are known to exploit virion-packaging tubules formed by virus-encoding non-structural proteins for viral spread in insect vectors. Tubules propelled actin-based tubule motility (ABTM) overcome membrane or tissue barriers To further understand which factors mediate ABTM, we utilized yeast two-hybrid and bimolecular fluorescence complementation assays test interactions between protein Pns10 of rice dwarf virus (RDV), a plant reovirus, its vector, the leafhopper...
Ag/MIL-100(Fe) core/sheath nanowire with controlled crystal growth of MIL-100(Fe) on the Ag surface was prepared for optimizing catalytic performance.
Photoactive metal-organic frameworks, MIL-100(Fe), with controllable thickness are coated on plasmonic Ag/AgCl nanowire, for boosting visible light photodegradation of rhodamine B and tetracycline hydrochloride. The morphology composition the obtained nano-heterostructure were investigated in detail by SEM imaging, TEM XRD patterns, FT-IR spectra, N2 adsorption-desorption curves TGA patterns. Photoelectric performance test suggested that a Z-scheme photocatalysis system efficient transfer...