Kate Adams
A5052317296- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Antibiotic Use and Resistance
- Long-Term Effects of COVID-19
- Sepsis Diagnosis and Treatment
- Intensive Care Unit Cognitive Disorders
- Antimicrobial Resistance in Staphylococcus
- Health Policy Implementation Science
- Tuberculosis Research and Epidemiology
- Pneumonia and Respiratory Infections
- Pharmacological Receptor Mechanisms and Effects
- Respiratory viral infections research
- Patient Satisfaction in Healthcare
- Bacterial Identification and Susceptibility Testing
- Antifungal resistance and susceptibility
- Homelessness and Social Issues
- Infective Endocarditis Diagnosis and Management
- Criminal Justice and Corrections Analysis
- Mycobacterium research and diagnosis
- Plant-based Medicinal Research
- Prenatal Substance Exposure Effects
- Emergency and Acute Care Studies
- Simulation-Based Education in Healthcare
- Counseling, Therapy, and Family Dynamics
- SARS-CoV-2 detection and testing
University of Hull
2020-2024
University of Colorado Anschutz Medical Campus
2023
University of Miami
2023
Pennsylvania State University
2023
University of East London
2021-2022
Hull Royal Infirmary
2020-2021
Nepal Health Research Council
2021
NIHR Clinical Research Network
2021
National Institute for Health Research
2021
National Records of Scotland
2021
BackgroundMany patients with COVID-19 have been treated plasma containing anti-SARS-CoV-2 antibodies. We aimed to evaluate the safety and efficacy of convalescent therapy in admitted hospital COVID-19.MethodsThis randomised, controlled, open-label, platform trial (Randomised Evaluation Therapy [RECOVERY]) is assessing several possible treatments hospitalised UK. The underway at 177 NHS hospitals from across Eligible consenting were randomly assigned (1:1) receive either usual care alone...
BackgroundAspirin has been proposed as a treatment for COVID-19 on the basis of its anti-thrombotic properties. We aimed to evaluate efficacy and safety aspirin in patients admitted hospital with COVID-19.MethodsIn this randomised, controlled, open-label, platform trial, several possible treatments were compared usual care hospitalised COVID-19. The trial took place at 177 hospitals UK, two Indonesia, Nepal. Eligible consenting adults randomly allocated 1:1 ratio either standard plus 150 mg...
BackgroundLow-dose corticosteroids have been shown to reduce mortality for patients with COVID-19 requiring oxygen or ventilatory support (non-invasive mechanical ventilation, invasive extracorporeal membrane oxygenation). We evaluated the use of a higher dose in this patient group.MethodsThis randomised, controlled, open-label platform trial (Randomised Evaluation Therapy [RECOVERY]) is assessing multiple possible treatments hospitalised COVID-19. Eligible and consenting adult clinical...
Escalating antimicrobial resistance worldwide necessitates urgent optimization of prescribing to preserve antibiotics for future generations. Early intravenous (iv) oral switch campaigns are one strategy that hospital-based stewardship programmes can incorporate minimize inappropriate antibiotic use. Yet, iv continue be offered longer than is clinically indicated, increasing hospital length stay, costs and placing patients at risk (e.g. cannula-related infections). This study aims identify...
Abstract Background Assessment of possible infection with SARS‐CoV‐2, the novel coronavirus responsible for COVID‐19 illness, has been a major activity services since first reports cases in December 2019. Objectives We report series 68 patients assessed at Regional Infection Unit UK. Methods Between 29 January 2020 and 24 February 2020, demographic, clinical, epidemiological laboratory data were collected. compared clinical features between not requiring admission reasons or antimicrobials...
Drug repurposing can be a successful approach to deal with the scarcity of cost-effective therapies in situations such as COVID-19 pandemic. Tetracyclines have previously shown efficacy preclinical acute respiratory distress syndrome (ARDS) models and initial predictions experimental reports suggest direct antiviral activity against SARS-CoV2. Furthermore, few clinical indicate their potential patients. In addition limitations scientific evidence, effectiveness tetracyclines ARDS has been...
Abstract Background COVID-19 medicines delivery units (CMDU) were established in late December 2021 to deliver early antiviral therapy patients classified as at risk with the aim of preventing hospitalization. Methods We performed a service evaluation 4 CMDUs England. assessed demographics and triage outcomes CMDU referral, uptake therapy, rate subsequent hospitalizations within 2 weeks referral. Results Over 3-week period, 4788 referred 3989 ultimately by CMDU. Overall, 832 (17%) judged...
Bacteraemia is a significant cause of mortality and healthcare expenditure. Evidence suggests that consultation by an infection specialist may improve outcomes.To review the characteristics outcomes patients seen newly implemented bacteraemia service.Retrospective data collected at time consultation. Economic analyses benchmarking were also performed.One hundred fifty-one service over 18-month period. Staphylococcus aureus was most common isolate central venous lines source. Antibiotics...
We present a case of an undifferentiated febrile illness in 59-year-old man from East Yorkshire. He was initially treated for leptospirosis due to the fact that he had farm exposure and findings acute kidney injury (AKI), thrombocytopenia raised alanine transferase (ALT) on his initial blood results. Serology tests later proved him have another rodent-borne illness: hantavirus. An investigation by Public Health England (formerly known as Protection Agency) (PHE) went prove presence same...
Abstract Clinical assessment of possible infection with SARS-CoV-2, the novel coronavirus responsible for outbreak COVID-19 respiratory illness, has been a major activity infectious diseases services in UK and elsewhere since first report cases December 2019. We our case series 68 patients, reviewed by Infectious Diseases Consultants at Regional Unit UK. prospectively evaluated service between 29 th Jan 2020 24 Feb 2020. Demographic, clinical, epidemiological laboratory data were collected....