A5024649043- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Urologic and reproductive health conditions
- Urological Disorders and Treatments
- Pelvic and Acetabular Injuries
- Renal cell carcinoma treatment
- Urinary Bladder and Prostate Research
- Soft Robotics and Applications
- Concrete and Cement Materials Research
- Bladder and Urothelial Cancer Treatments
- Neuroendocrine Tumor Research Advances
- Genetic and Kidney Cyst Diseases
- Genital Health and Disease
- Mechanical Engineering and Vibrations Research
- Fire effects on concrete materials
- Nonmelanoma Skin Cancer Studies
- Pelvic floor disorders treatments
- Hernia repair and management
- Cellular Mechanics and Interactions
- Angiogenesis and VEGF in Cancer
- Urinary Tract Infections Management
- Cancer, Lipids, and Metabolism
- Cancer Diagnosis and Treatment
- Teleoperation and Haptic Systems
- Aerospace Engineering and Control Systems
The University of Tokyo
2011-2025
Chiba University
2023-2024
Japanese Foundation For Cancer Research
2024
Tokyo Metropolitan Police Hospital
2017-2018
Iwate University
2003-2010
Angiogenesis is a complex process, which accomplished by reiteration of modules such as sprouting, elongation and bifurcation, that configures branching vascular networks. However, details the individual collective behaviors endothelial cells (ECs) during angiogenic morphogenesis remain largely unknown. Herein, we established time-lapse imaging computer-assisted analysis system quantitatively characterizes in sprouting angiogenesis. Surprisingly, ECs moved backwards forwards, overtaking each...
Abstract The objective of this study was to identify the prognostic factors and propose a new risk model in metastatic castration-resistant prostate cancer (mCRPC) patients. clinical data were retrospectively obtained for 102 mCRPC patients who received treatment between 2005 2018 at University Tokyo Hospital. We investigated pathological parameters, including prostate-specific antigen (PSA) kinetic profiles under androgen deprivation treatment, identified predictors overall survival (OS)....
Background: The aim of this study is to describe the first series six patients undergoing Retzius-sparing robot-assisted radical prostatectomy (rs-RARP) using hinotori surgical robot system (hinotori SRS) and compare treatment outcomes with those achieved da Vinci platform. Methods: This included 20 cases involving rs-RARP procedure (hinotori: N = 6; Vinci: 14) that were performed between May 2021 April 2024 in a single institution. Results: No significant differences observed groups...
The objective of the present study was to describe our novel suturing technique, "Fish-hook", during urethra-vesico anastomosis in a robot-assisted radical prostatectomy procedure. medical information extracted from clinical records 348 patients with prostate cancer who underwent at Chiba Tokushukai Hospital between April 2017 and June 2023. impact "Fish-hook" technique on surgical outcomes examined by statistical analysis. not used 123 (Group 1) 225 2). time for significantly shorter Group...
This study compared the detection rates for clinically significant prostate cancer (CSPC) between magnetic resonance imaging and ultrasonography (MRI/US)-fusion-targeted biopsy (TB), systematic (SB) combination of TB SB.This prospective evaluated simultaneous SB consecutive patients with suspicious lesions that were detected using pre-biopsy multiparametric MRI. A commercially available real-time virtual sonography system was used to perform MRI/US-fusion transperineal technique. The...
Although photodynamic-diagnosed transurethral resection of bladder cancer (PDD-TURBT) and Bacillus Calmette-Guérin (BCG) intravesical instillation are the two representative therapies for non-muscle invasive (NMIBC), no studies directly compare their efficacy. We evaluated outcome PDD-TURBT alone compared with white light TURBT BCG therapy analyzed efficacy both depending on characteristics tumors. retrospectively intermediate- high-risk NMIBC patients treated (the PDD group) or using...
We aimed to identify prognostic factors of cancer-specific survival (CSS) in non-metastatic castration-resistant prostate cancer (M0CRPC) patients. The final analysis this retrospective cohort included 82 patients who were diagnosed as M0CRPC between 1998 and 2018 at the University Tokyo Hospital. CRPC was defined prostate-specific antigen (PSA) progression (increased PSA ≥ 25% 2 ng/mL above nadir or detection a metastatic lesion). median value age time 76 (range 55-94) years 2.84 2.04-22.5)...
Objectives To evaluate the detection rates of clinically significant prostate cancer classified according to imaging reporting and data system scoring using magnetic resonance imaging/ultrasound rigid fusion targeted biopsy. Methods A total 339 patients underwent transperineal biopsy in our institution between January 2015 July 2017. Patients with category 1 or 2 those a pre‐biopsy prostate‐specific antigen value >30 ng/mL were excluded from this study. Finally, 310 recruited. Results The...
Abstract Background The objective of this study is to investigate the clinical significance and risk factors upgrading in International Society Urological Pathology (ISUP) Grade Group System men undergoing robot-assisted radical prostatectomy (RARP) for prostate cancer. Methods A total 583 patients diagnosed with cancer by systematic biopsy were treated RARP without neoadjuvant therapy from November 2011 December 2018. Clinicopathological data obtained our records. ISUP grade (IGU) was...
The aging and damage of concrete buildings structures is a problem in modern society. This especially true for nuclear power plant buildings, which are required to have high safety standards. In this study, molecular dynamics simulations were performed obtain mechanical properties silicate minerals, including quartz, used as an aggregate concrete. We also attempted clarify phenomena fracture. Mechanical each mineral (Young's modulus, Poisson's ratio, maximum stress) obtained by performing...
Abstract This study was to show the impact of ‘prostate-muscle index (PMI)’, which we developed as a novel pelvic cavity measurement, in patients undergoing robot-assisted radical prostatectomy (RARP). We defined PMI ‘distance between inner edge obturator internus muscle and lateral prostate at magnetic resonance imaging (MRI) slice showing maximum width prostate’. Seven hundred sixty underwent RARP University Tokyo Hospital from November 2011 December 2018. MRI results were unavailable 111...
Diagnosis of renal cell carcinoma (RCC) in patients with autosomal dominant polycystic kidney disease (ADPKD) is challenging and often delayed due to accompanying multiple cysts. Sometimes, it difficult distinguish RCC from cyst infection or hemorrhage. We herein present the case a patient ADPKD undergoing long-term hemodialysis whose sarcomatoid was diagnose confirmed via nephrectomy. A 53-year-old male, since 20 years for end-stage secondary ADPKD, admitted our hospital 3-week history...
Abstract Background There has been a limited number of reports on the significance and risk factors urethrovesical anastomotic urinary leakage (AUL) following robot-assisted radical prostatectomy (RARP). We aimed to analyze clinical AUL evaluated its factors. Methods conducted multi-institutional study review patients with prostate cancer undergoing RARP in three centers (The University Tokyo Hospital, Mitsui Memorial Chiba Tokushukai Hospital). “Positive AUL” was defined as extravasation at...
To investigate changes in uroflowmetry parameters men undergoing robot-assisted radical prostatectomy (RARP) for prostate cancer.Four hundred and twenty-eight patients received testing before after RARP from November 2011 to December 2018. Clinicopathological data, including age, initial prostate-specific antigen (PSA), volume, clinical stage, body mass index (BMI), parameters, core lower urinary tract symptom scores (CLSS) were retrospectively obtained records. Changes analyzed statistical...
<title>Abstract</title> Upper extremity complications are often a problem in robot-assisted pelvic surgery (RAPS) with the lithotomy-Trendelenburg position (LT-position). This study focused on upper contact pressure (UEP) and examined relationship between UEP complications. From May 2020 to April 2022 at University of Tokyo Hospital, was measured 155 patients undergoing RARP 20 RARC. A total 350 sets were investigated this study. using portable interface sensor (Palm QR , Cape CO., Kanagawa,...
Abstract A total of 739 patients underwent RARP as initial treatment for PCa from November 2011 to October 2018. Data on BCR status, clinical and pathological parameters were collected the records. After excluding cases with neoadjuvant and/or adjuvant therapies, presence lymph node or distant metastasis, positive SM, a 537 eligible final analysis. The median follow-up experimental cohort was 28.0 (interquartile: 18.0–43.0) months. We identified International Society Urological Pathology...
Abstract Upper extremity complications are often a problem in robot-assisted pelvic surgery (RAPS) with the lithotomy-Trendelenburg position (LT-position). This study focused on upper contact pressure (UEP) and examined relationship between UEP complications. From May 2020 to April 2022 at University of Tokyo Hospital, was measured 155 patients undergoing RARP 20 RARC. A total 350 sets were investigated this study. using portable interface sensor (Palm Q, Cape CO., Kanagawa, Japan)...
Inguinal hernia (IH) is a common postoperative complication after robot-assisted radical prostatectomy (RARP). We developed novel clipping technique for the prevention of IH developing RARP.
Abstract The concrete in nuclear power plant reactor buildings is exposed to neutron radiation, making it critical evaluate and predict its deterioration under irradiation. observed expansion of irradiated believed be caused by the aggregate minerals, but mechanisms behind this process are not well understood. This study uses molecular dynamics simulations investigate mechanical properties fracture phenomena a range silicate minerals that popular as aggregates. Ten targeted: ‐quartz,...
Rapid prototyping is a technology using CAD/CAM, and molding machine, which manufactures prototype model rapidly. Since it can make products with complex shapes of three dimensions, the cost time for development reduced. It convenient in production wide range prototypes, particularly product's development. The purpose our research was to manufacture an effective motor reducer develop robot high mobility. To achieve this, necessary both reduce weight 3D processing machine rigidity. In this...
Abstract Background Vulvar Paget’s disease (VPD) is a rare malignant disorder originating in the external genitalia. It occasionally invades into urethral or vaginal mucosa of female, making surgical treatment more complicating. In case invasion cells, systematic mapping biopsy standard care to determine range resection. Resection and simple skin grafting often result stricture after surgery, which severely deteriorates patient’s quality life. Case presentation We applied new technique...