Bok Kyung Han

ORCID: 0000-0003-3139-0286
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Research Areas
  • Exercise and Physiological Responses
  • Phytochemicals and Antioxidant Activities
  • Nutrition, Health and Food Behavior
  • Food composition and properties
  • Immunotherapy and Immune Responses
  • Proteins in Food Systems
  • Essential Oils and Antimicrobial Activity
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Antioxidant Activity and Oxidative Stress
  • Ginseng Biological Effects and Applications
  • Immune Cell Function and Interaction
  • Pharmacological Effects of Natural Compounds
  • Postharvest Quality and Shelf Life Management
  • Silk-based biomaterials and applications
  • Polysaccharides Composition and Applications
  • Dye analysis and toxicity
  • Biochemical and Structural Characterization
  • Skin Protection and Aging
  • Herbal Medicine Research Studies
  • Phytochemical compounds biological activities
  • Free Radicals and Antioxidants
  • Consumer Attitudes and Food Labeling
  • Composting and Vermicomposting Techniques
  • Orthopaedic implants and arthroplasty
  • Agriculture, Soil, Plant Science

Korea University
2001-2025

Abstract Obesity, often driven by high-fat diets (HFD), is a major global health issue, necessitating effective preventive measures. Tetragonia tetragonoides, plant with known medicinal properties, has not been extensively studied for its effects on HFD-induced obesity and related genetic changes in mice. This study explores the impact of tetragonoides extract (TTE; 300 mg/kg) obesity-related traits C57BL/6J male mice, focus transcriptomic liver white adipose tissue (WAT). Over eight weeks,...

10.1093/bbb/zbaf001 article EN Bioscience Biotechnology and Biochemistry 2025-01-11

The demand for sustainable and functional plant-based products is on the rise. Plant proteins polysaccharides often provide emulsification stabilization properties to food ingredients. Recently, chickpea cooking water, also known as aquafaba, has gained popularity a substitute egg whites in sauces, foams, baked goods due its foaming emulsifying capacities. This study presents modified eco-friendly process obtain water from faba beans isolate characterize foam-inducing components. isolated...

10.3390/foods12183391 article EN cc-by Foods 2023-09-11

Despite the advancements in vaccination research and practices, influenza viruses remain a global health concern. Inducing robust immune response by is especially challenging elderly, immunocompromised, persons with chronic illnesses. Polysaccharides derived from food may act as safe readily accessible means to boost system during vaccination. In this study, we investigated whether crude polysaccharides carrot pomace (CPP) could stimulate innate cell function promote vaccine immunogenicity....

10.3390/nu12092740 article EN Nutrients 2020-09-09

Abstract BACKGROUND In this study, the tri‐peptides Gly‐Glu‐Tyr ( GEY ) and Gly‐Tyr‐Gly GYG ), identified previously as active compounds from silk peptide E5K6 , significantly stimulated basal insulin‐mediated glucose uptake by 3T3‐L1 fibroblasts in a dose‐dependent manner. RESULTS Synthetic peptides at concentration of 500 µmol L −1 increased transporter type 4 expression 157% 239%, respectively. Differentiation cells into adipocytes leads to accumulation intracellular fat droplets, 250...

10.1002/jsfa.7067 article EN Journal of the Science of Food and Agriculture 2014-12-31

Sword bean has been known as a traditional medicinal plant to treat cancer, sinus infection, and suppurative disease. It also possesses hypertension-relieving, antioxidation, antibacterial effects. However, studies on the efficacy of sword are limited mature beans. Few have focused immature pod (ISBP). Therefore, this study aimed investigate anti-inflammatory effect ISBP in RAW264.7 cells stimulated with lipopolysaccharide (LPS). After LPS-induced were treated at concentrations (0.5, 1, 2, 5...

10.1089/jmf.2020.4733 article EN Journal of Medicinal Food 2020-11-01

The maintenance of bone is dependent on both osteoclasts, which break down bone, and osteoblasts, build new bone. Various bone-related disorders, including osteoporosis, can occur as a result an imbalance between these two cell types. Prolonged use currently available resorption inhibitors may show side effects. Therefore, developing novel preventive material effectively inhibits osteoclast differentiation could be beneficial. This study planned to investigate the inhibitory effect wheat...

10.1089/jmf.2022.k.0131 article EN Journal of Medicinal Food 2023-07-01

Abstract Ammonia from livestock manure acts as a precursor to produce particulate matter (PM) by reacting with atmospheric chemical components volatilized various sources. itself toxic substance human health, and thus has direct or indirect adverse effects on health. This study aimed verify the effectiveness mechanism of action Saccharomyces boulardii (SB) in reducing ammonia emission manure. The specific ability SB was confirmed through comparative verification S. cerevisiae (SC) belonging...

10.1186/s13765-021-00600-x article EN cc-by Applied Biological Chemistry 2021-03-10

Fatigue is a common phenomenon usually observed in healthy, as well nonhealthy, individuals that affects their performance and quality of life. Efficient supplementation to relieve fatigue significant importance. This study was designed investigate the efficacy three prescreened natural resources (Cervus elaphus L. [CEL], Angelica gigas Nakai [AGN], Astragalus membranaceus Bunge [AMB]) against symptoms induced by heavy exercise. Effects on muscle endurance capacity during exercise were...

10.1089/jmf.2020.4743 article EN Journal of Medicinal Food 2021-06-01

The objective of this study was to evaluated the photoprotective effects porcine placenta extract (PPE) on ultraviolet B (UVB)-induced oxidative stress in human keratinocytes (HaCaT) evaluate its functional activities as a skin food ingredient. PPE prepared by subcritical water extraction termed SPE, and subsequently digested enzymes prepare E-SPE. Increased intracellular reactive oxygen species (ROS) levels (192.0%) induced UVB were decreased SPE had more effective ROS scavenging activity...

10.5851/kosfa.2015.35.2.164 article EN Korean Journal for Food Science of Animal Resources 2015-04-30

Fatigue is a common complaint among people under stress, causing an array of negative effects on physical function. In this study, we investigated the antifatigue and anti-inflammatory Cervus elaphus L., Angelica gigas Nakai, Astragalus membranaceus Bunge complex extracts (CAA) using treadmill stress test in animal models. The mice were administered various doses CAA (50-200 mg/kg bw per day) once daily for 21 days. After exhaustive exercise, running time CAA-treated increased 1.5 times;...

10.1089/jmf.2022.k.0103 article EN Journal of Medicinal Food 2022-12-01

Preserving the quality of freshly cut fruits is essential for food marketing. This study aimed to evaluate anti-browning effect rice bran extract (RE) added a vitamin C mixture (VCM), which widely used as an agent. Freshly apples were prepared using following processes: raw material selection, washing, cutting, soaking, and packaging. A comparison soaked with 3% VCM combined 1% RE (VR) treated 4% showed that L* BI values had similar levels. After 12 days storage, amount yeast mold in after...

10.3390/agronomy12010086 article EN cc-by Agronomy 2021-12-30

Asthma is one of the most common inflammatory diseases lung worldwide. There has been considerable progress in recent studies to treat and prevent allergic asthma, however, various side effects are still observed clinical practice. Six-week-old male BALB/c mice were orally administered with either sword bean pod extracts (SBP; 100 or 300 mg/kg) dexamethasone (DEX; 5 once daily over 3 weeks, followed by ovalbumin sensitization (OVA/Alum.; intraperitoneal administration, 50 μg/2 mg/per mouse)....

10.3390/molecules27196317 article EN cc-by Molecules 2022-09-25

Abstract In this study, we optimized the composition of browning inhibitor for apples and established a prediction model concentration in mass‐processed fresh‐cut based on electrical conductivity measurements. The “Fuji” that were harvested Chungju, Korea, used study. Vitamin C mixture (VCM) trehalose (Tre) as inhibitors at 4% ratio. reaction under Δ3 BI (browning index) 5 days was defined target shelf‐life apple flesh. ΔBI VCM Tre lower than by 4%. It is revealed highly correlated with its...

10.1111/1750-3841.17217 article EN cc-by Journal of Food Science 2024-06-26

Skeletal muscle atrophy refers to the loss of strength and mass due decreased protein synthesis or increased degradation. Various conditions can cause atrophy, including aging, heart disease, chronic illness, obstructive pulmonary kidney failure, diabetes, AIDS, cancer, sepsis, steroid use. natural materials have been studied for prevention atrophy. In this study, we found that extracts from sprouts purple wheat, Arriheuk, prevented

10.1089/jmf.2024.k.0104 article EN Journal of Medicinal Food 2024-10-10

Ginsenosides, active compounds derived from Panax ginseng, exhibit promising potential in enhancing physical performance. This study investigates the impact of UG0712 (UG), a novel ginsenoside compound, on endurance capacity, body weight, organ weights, blood parameters, and specific transcriptomic changes liver muscle tissues using C57BL/6N mouse model. The mice received UGs orally at three doses: UG50 (50 mg/kg), UG100 (100 UG200 (200 mg/kg) for specified duration. Endurance physiological...

10.1089/jmf.2024.k.0089 article EN Journal of Medicinal Food 2024-11-23

Cardiovascular disease (CVD) is the primary cause of mortality worldwide and imposes a significant social burden on many countries. This study assessed health economic benefits omega-3 associated with CVD. The meta-analysis estimated risk ratio (RR) absolute reduction (ARR), impact was calculated using direct indirect costs related to CVD treatments in Korean adults. A total 33 studies were included outcomes, 80,426 participants intervention group 80,251 control group. determined (RR = 0.92,...

10.3390/healthcare11162365 article EN Healthcare 2023-08-21
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