A5030926273- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- Monoclonal and Polyclonal Antibodies Research
- T-cell and B-cell Immunology
- Cytokine Signaling Pathways and Interactions
- interferon and immune responses
- Calcium signaling and nucleotide metabolism
- Herbal Medicine Research Studies
- Immune Response and Inflammation
Chungnam National University
2016-2021
Rheumatoid arthritis (RA) is an autoimmune disease that starts with decreased tolerance to modified self-antigens and eventually leads synovitis destruction of bone cartilage. Age a risk factor for developing RA. Major changes in the immune system come age due chronic oxidative stress on deoxyribonucleic acid (DNA) damage pathway, somatic mutation, modifications autoantigens, T cell activation fibroblast-like synoviocytes (FLS). Reactive oxygen species (ROS) generated by nicotinamide adenine...
Despite the advancements in vaccination research and practices, influenza viruses remain a global health concern. Inducing robust immune response by is especially challenging elderly, immunocompromised, persons with chronic illnesses. Polysaccharides derived from food may act as safe readily accessible means to boost system during vaccination. In this study, we investigated whether crude polysaccharides carrot pomace (CPP) could stimulate innate cell function promote vaccine immunogenicity....
Rheumatoid arthritis (RA) is a common autoimmune disease characterized by immune cell infiltration of the synovium, leading to loss cartilage, bone, and joint function. Although regulatory T (Treg) cells are thought modulate initiation progression RA, consensus has yet be reached regarding function composition Treg in RA patients. To address these discrepancies, we analyzed not only total frequency but also that subpopulations peripheral blood patients healthy controls flow cytometry. We...
Abstract Dendritic cells (DC) are specialized antigen-presenting that initiate and orchestrate the body’s immune response to bridge innate adaptive systems. Here we report developing a standardized evaluation system for immunity-boosting functional foodstuffs using bone marrow-derived dendritic cells. A DC-based can indicate type, magnitude, specificity of responses elicited by an immune-boosting food item. We monitored expression profile DC maturation markers, including CD11b, CD11c, CD40,...