A5036661449- Viral Infections and Immunology Research
- interferon and immune responses
- IL-33, ST2, and ILC Pathways
- Eosinophilic Disorders and Syndromes
- Cytomegalovirus and herpesvirus research
- Vitamin C and Antioxidants Research
Zhengzhou University
2022-2024
Abstract Pulmonary edema that comes on suddenly is the leading cause of mortality in hand‐foot‐and‐mouth disease (HFMD) patients; however, its pathogenesis still largely unclear. A range research suggest immunopathogenesis during occurrence pulmonary severe HFMD patients. Herein, to investigate potential mechanism immune dysregulation development upon Enterovirus (EV) infection, we established mouse infection models for Enteroviruses (EVs) including Coxsackievirus (CV) A6, A71 (EVA71), and...
ABSTRACT Hand, foot, and mouth disease (HFMD) is a serious pediatric infectious that causes immeasurable physical mental health burdens. Currently, there lack of information on the mechanisms HFMD severity early diagnosis. We performed metabolomic profiling sera from 84 Enterovirus A71 (EV-A71) infections 45 control individuals. Targeted metabolomics assays were employed to further validate some differential metabolic molecules. identified significant molecular changes in patients compared...