A5037023029- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Breast Cancer Treatment Studies
- Estrogen and related hormone effects
- Cervical Cancer and HPV Research
- Breast Lesions and Carcinomas
- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Sarcoma Diagnosis and Treatment
- Breast Implant and Reconstruction
- Global Cancer Incidence and Screening
- Cancer Risks and Factors
- Pelvic floor disorders treatments
- Protease and Inhibitor Mechanisms
- Cancer Diagnosis and Treatment
- Genital Health and Disease
- RNA Research and Splicing
- Cancer Cells and Metastasis
- Cancer and Skin Lesions
- Testicular diseases and treatments
- Urinary and Genital Oncology Studies
- Colorectal and Anal Carcinomas
- Cancer-related molecular mechanisms research
- Angiogenesis and VEGF in Cancer
- Cancer Treatment and Pharmacology
Universitat Autònoma de Barcelona
2007-2023
Vall d'Hebron Hospital Universitari
2005-2014
Hospital Materno-Infantil
2000-2013
Hospital Arnau de Vilanova
2009
Weatherford College
2007
Universitat de Barcelona
1995
Abstract Endometrial cancer (EC) is the most frequent of invasive tumors female genital tract. Although usually detected in its initial stages, a 20% patients present with advanced disease. To date, no characterized molecular marker has been validated for diagnosis EC. In addition, new methods prognosis and classification EC are needed to combat this deadly We thus aimed identify markers evaluate their validity on endometrial aspirates. Gene expression screening 52 carcinoma samples series...
Abstract Endometrial carcinoma is the most common gynecological malignant disease in industrialized countries. Two clinicopathological types of endometrial have been described, based on estrogen relation and grade: endometrioid (EEC) non-EEC (NEEC). Some molecular events that occur during development characterized, showing a dualistic genetic model for EEC NEEC. However, bases tumorigenesis are not clearly elucidated. In present work, we attempted to identify new genes could trigger cell...
We have described recently the Ets family transcription factor, ERM/ETV5, specifically up-regulated in endometrioid endometrial carcinoma (EEC) and associated with myometrial infiltration. members been correlated to tumor progression by up-regulating expression of matrix-degrading proteases. In present study, we investigated possibility that EEC, ERM/ETV5 may act inducing genes involved extracellular matrix remodeling. Unraveling molecular events initiation invasion would represent an...
Endometrial cancer, the most common gynecological malignancy in western countries, is characterized by a favorable prognosis. Nonetheless, deep myometrial invasion correlates with more undifferentiated tumors, lymph-vascular invasion, node involvement and decreased global survival. We have described previously Ets family member ERM/ETV5 specifically upregulated endometrial endometrioid carcinoma (EEC) associated infiltration. To understand role of this transcription factor during...
Abstract Endometrial carcinoma is the most common malignancy of female genital tract in industrialized countries. Metastasis major cause endometrial cancer deaths. Therefore, there a vital need for clinically relevant vivo models allowing elucidation molecular and cellular mechanisms underlying metastatic behavior. In this study, we describe an innovative experimental orthotopic model human carcinoma. Implantation bifurcation uterine horns resulted tumors integrated into myometrial...
We assessed maternal and neonatal outcome in women diagnosed with breast cancer during pregnancy.Retrospective single-centre cohort study of 25 consecutive pregnant (mean age 36 years) treated for between 2000 2011. Management was individualized according to type tumor time gestation at diagnosis.Twelve patients were the second trimester. BI-RADS category <3 mammographic lesions 7 patients. A suspicious area detected by ultrasound 20 21 who underwent studies. Nineteen had positive hormone...