Akinori Sawamura

ORCID: 0000-0003-3147-3073
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About
Contact & Profiles
Research Areas
  • Cardiovascular Function and Risk Factors
  • Heart Failure Treatment and Management
  • Cardiac Structural Anomalies and Repair
  • Viral Infections and Immunology Research
  • Mechanical Circulatory Support Devices
  • Cardiomyopathy and Myosin Studies
  • Cardiac Arrest and Resuscitation
  • Cardiac Imaging and Diagnostics
  • Cardiac Valve Diseases and Treatments
  • Cardiovascular Effects of Exercise
  • Cardiac pacing and defibrillation studies
  • Blood Pressure and Hypertension Studies
  • Hemodynamic Monitoring and Therapy
  • Cardiac electrophysiology and arrhythmias
  • Aldose Reductase and Taurine
  • Heart Rate Variability and Autonomic Control
  • Cardiac Health and Mental Health
  • Cardiovascular Issues in Pregnancy
  • Cardiac Ischemia and Reperfusion
  • Cardiac, Anesthesia and Surgical Outcomes
  • Hormonal Regulation and Hypertension
  • Eosinophilic Disorders and Syndromes
  • Atrial Fibrillation Management and Outcomes
  • Frailty in Older Adults
  • Coronary Interventions and Diagnostics

Ichinomiya Municipal City Hospital
2019-2024

Nagoya University
2013-2020

Nagoya University Hospital
2019

Nagoya City University
2018

Asahi University
2017

Mizuho (Japan)
2017

University of Rochester Medical Center
2016

Komaki City Hospital
2011

Osaka University
1987-1988

Fulminant myocarditis (FM) presents various abnormal findings on ECG, the prognostic impact of which has not been fully elucidated. The aim this study was therefore to clarify value ECG data in FM patients supported by venoarterial extracorporeal membrane oxygenation (VA-ECMO).Methods and Results:In multicenter chart review, we investigated 99 with VA-ECMO. final cohort consisted 87 (mean age, 52±16 years; female, 42%) after 12 who required conversion other forms mechanical circulatory...

10.1253/circj.cj-18-0136 article EN Circulation Journal 2018-05-31

Journal Article Protection by oral pretreatment with taurine against the negative inotropic effects of low-calcium medium on isolated perfused chick heart Get access AKIHIKO SAWAMURA, SAWAMURA Search for other works this author on: Oxford Academic PubMed Google Scholar JUNICHI AZUMA, AZUMA * *Address reprint requests: Dr Junichi Azuma, The Third Department Internal Medicine, Osaka University Medical School, Fukushima 1-1-50, Fukushima-ku, 553, Japan. HISATO HARADA, HARADA HIROSHI HASEGAWA,...

10.1093/cvr/17.10.620 article EN Cardiovascular Research 1983-10-01

Cardiac recovery and prevention of end-organ damage are the cornerstones establishing successful bridge to (BTR) in patients with fulminant myocarditis (FM) supported percutaneous venoarterial extracorporeal membrane oxygenation (VA-ECMO). However, timing method BTR prediction still remain unclear. We aimed develop a model for FM VA-ECMO.Methods Results:This was retrospective multicenter chart review enrolling 99 (52±16 years; female, 42%) treated VA-ECMO. The S-group comprised who...

10.1253/circj.cj-17-0549 article EN Circulation Journal 2017-10-26

The effect of the sulphur amino acid, taurine, on biochemical changes induced by a toxic dose isoprenaline was examined in chick hearts. Isoprenaline treatment (80 and 240 mg·kg−1 subcutaneously twice day for four days) caused dependent increase heart to body weight ratio. administration substantial accumulation calcium profound decrease adenosine triphosphate content creatine phosphokinase activity myocardium. A pronounced lipoperoxide phospholipid reduced glutathione concentrations were...

10.1093/cvr/22.6.407 article EN Cardiovascular Research 1988-06-01

Hemodynamic parameters at rest are known to correlate poorly with peak oxygen uptake (VO2) in heart failure. However, we hypothesized that hemodynamic could predict exercise capacity patients left ventricular assist device (LVAD), because LVAD pump rotational speed does not respond during exercise. Therefore, investigated the relationships between (measured right catheterization) and cardiopulmonary testing) implantable LVAD.We performed a retrospective medical record review of who received...

10.1177/0391398820949888 article EN The International Journal of Artificial Organs 2020-08-12

The acute haemodynamic effects of taurine were studied in normal and beta blocker (propranolol) or calcium antagonist (diltiazem) treated rabbits with experimentally produced chronic aortic regurgitation. administration (25 mg.kg-1) did not affect heart rate left ventricular end diastolic pressure but significant increases dP/dtmax, cardiac output, systolic control hearts, indicating that intravascularly administered substantially increased performance. In propranolol (1 significantly...

10.1093/cvr/21.4.241 article EN Cardiovascular Research 1987-04-01

Recently, it has become increasingly recognized that pulmonary hypertension (PH) is a particularly threatening result of left-sided heart disease. However, there have been few investigations the impact cardiopulmonary exercise testing (CPX) variables on PH in dilated cardiomyopathy (DCM). We evaluated usefulness crucial CPX for detecting elevated arterial pressure (PAP) patients with DCM.Ninety subjects DCM underwent cardiac catheterization and at our hospital. Receiver operator...

10.1111/anec.12308 article EN cc-by-nc-nd Annals of Noninvasive Electrocardiology 2016-02-01

Abstract The spleen has been recognized as an important organ that holds a reserve of 20% to 30% the total blood volume. Spleen contraction and splenic volume reduction occur in patients with hypovolemic shock. However, change association between size hemodynamic parameters remain unclear advanced heart failure (HF) who need left ventricular assist device (LVAD) support. This study was performed investigate relationship before after LVAD implantation HF. We enrolled 20 HF on All underwent...

10.1111/aor.13658 article EN Artificial Organs 2020-02-04

The clinical significance of worsening renal function (WRF) in elderly patients with acute decompensated heart failure (ADHF) is not completely understood. We compared the conditions between younger and ADHF after appearance WRF to establish its prognostic influence.We included 654 consecutive (37% women) admitted for ADHF. divided into four groups according their age (<80 years, under-80, n=331; ≥80 over-80, n=323) statuses (either or non-WRF group). defined as an increase serum creatinine...

10.36628/ijhf.2020.0050 article EN cc-by-nc International Journal of Heart Failure 2021-01-01

Fast-progressing vascular calcification (VC) is accompanied by renal atrophy and functional deterioration along with atherosclerosis in patients chronic kidney disease (CKD). However, the relationship between VC progression and/or morphological changes remains unclear.We included 70 asymptomatic CKD without hemodialysis our study. To identify temporal variations, coronary artery score (CACS), abdominal aortic index (ACI), parenchymal volume (RPVI) were determined via spiral computed...

10.5551/jat.39271 article EN Journal of Atherosclerosis and Thrombosis 2017-01-01

An abnormal circadian blood pressure (BP) profile is considered a risk factor for cardiovascular disease. However, its significance in heart failure patients with nonischemic etiology unknown. Herein, we investigated the prognostic value of BP dilated cardiomyopathy (NIDCM).We enrolled 114 NIDCM (76 males, mean age 53.1 years). The percent nighttime fall (%NBPF) was defined using ambulatory monitoring as decrease systolic from daytime. All were divided into three groups: dipper (%NBPF ≥10),...

10.1159/000446868 article EN Cardiology 2016-08-18
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