Marisa Varrenti

ORCID: 0000-0003-4375-5991
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About
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Research Areas
  • Cardiovascular Health and Disease Prevention
  • Cardiac electrophysiology and arrhythmias
  • Cardiac Structural Anomalies and Repair
  • Viral Infections and Immunology Research
  • Transplantation: Methods and Outcomes
  • Mechanical Circulatory Support Devices
  • Cardiac pacing and defibrillation studies
  • Cardiac Arrhythmias and Treatments
  • Atrial Fibrillation Management and Outcomes
  • Blood Pressure and Hypertension Studies
  • Cardiovascular Function and Risk Factors
  • Cardiovascular Effects of Exercise
  • Cardiovascular Issues in Pregnancy
  • Cardiac Imaging and Diagnostics
  • Heart Rate Variability and Autonomic Control
  • Eosinophilic Disorders and Syndromes
  • Cardiomyopathy and Myosin Studies
  • Cardiovascular Disease and Adiposity
  • Alcohol Consumption and Health Effects
  • Aortic Disease and Treatment Approaches
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cardiac Valve Diseases and Treatments
  • Nitric Oxide and Endothelin Effects
  • Cerebrovascular and Carotid Artery Diseases
  • ECG Monitoring and Analysis

Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2016-2025

Ospedale Maggiore
2015-2025

University of Milano-Bicocca
2013-2024

Metropolitana Milanese (Italy)
2024

Policlinico San Matteo Fondazione
2017

Istituti di Ricovero e Cura a Carattere Scientifico
2017

University of Pavia
2017

Vita-Salute San Raffaele University
2017

University of Parma
2016

University of Milan
2016

There is controversy about the outcome of patients with acute myocarditis (AM), and data are lacking on how admitted suspected AM managed. We report characteristics, in-hospital management, long-term based a retrospective multicenter registry from 19 Italian hospitals.A total 684 recent onset symptoms (<30 days) were screened between May 2001 February 2017. Patients >70 years age those >50 without coronary angiography excluded. The final study population comprised 443 (median age, 34 years;...

10.1161/circulationaha.118.035319 article EN Circulation 2018-05-15

Previous reports have suggested that despite their dramatic presentation, patients with fulminant myocarditis (FM) might better outcome than those acute nonfulminant (NFM). In this retrospective study, we report and changes in left ventricular ejection fraction (LVEF) a large cohort of FM compared NFM.The study population consists 187 consecutive admitted between May 2001 November 2016 diagnosis (onset symptoms <1 month) whom 55 required inotropes and/or mechanical circulatory support the...

10.1161/circulationaha.117.026386 article EN Circulation 2017-06-03

Objective— Aim of this study was to evaluate changes in LCAT (lecithin:cholesterol acyltransferase) concentration and activity patients with an acute coronary syndrome, investigate if these are related the compromised capacity HDL (high-density lipoprotein) promote endothelial nitric oxide (NO) production, assess rhLCAT (recombinant human LCAT) can rescue defective vasoprotective function. Approach Results— Thirty ST-segment–elevation myocardial infarction (STEMI) were enrolled, plasma...

10.1161/atvbaha.118.311987 article EN Arteriosclerosis Thrombosis and Vascular Biology 2019-03-21

Objective: The role of risk factors on the progression arterial stiffness has not yet been extensively evaluated. aim current longitudinal study was to evaluate determinants PWV over a 4 years follow-up period in hypertensive subjects.Materials and Methods: We enrolled 333 consecutive outpatients 18–80 aged, followed by Hypertension Unit St. Gerardo Hospital (Monza, Italy). At baseline anamnestic, clinical, BP, laboratory data cfPWV were assessed. performed examination with median time...

10.1080/08037051.2017.1378069 article EN Blood Pressure 2017-09-18

wide antral pulmonary vein isolation (PVI) is effective for treating paroxysmal atrial fibrillation (PAF), although time-demanding. We investigated the impact of a standardized ablation protocol by using bidirectional transeptal steerable sheath, high-density mapping and very high-power-short-duration (vHPSD) catheters on procedure timing, efficacy, safety. consecutive PAF patients free from previous ablations undergoing PVI alone between January 2022 March 2023 were prospectively enrolled....

10.3389/fcvm.2025.1552340 article EN cc-by Frontiers in Cardiovascular Medicine 2025-02-18

Acute myocarditis (AM) is an inflammatory injury of the myocardium secondary to infections, systemic autoimmune disorders, medications, or toxic agents. The patient's genetic underground a likely concurrent aetiology/contributory mechanism recently implicated in proportion AM. This review focuses on some critical new concepts AM, updated indications for endomyocardial biopsy when cardiac magnetic resonance imaging not sufficient feasible, and estimation long-term events after discharge....

10.1093/eurheartjsupp/suae105 article EN cc-by-nc European Heart Journal Supplements 2025-02-01

Myocardial infarction with nonobstructive coronary arteries (MINOCA) is an increasingly recognized condition, a higher incidence in women, characterized by myocardial injury without significant artery obstruction. Sex-specific differences play critical role its pathophysiology, clinical presentation, and response to treatment. While the underlying mechanisms of MINOCA are diverse—including microvascular dysfunction, spasm, plaque rupture, dissection, thromboembolism—women more frequently...

10.20944/preprints202502.1620.v1 preprint EN 2025-02-20

Arrhythmogenic cardiomyopathy is a heart disease in which the muscle replaced by scar tissue. This main substrate for development of malignant ventricular arrhythmias. Sudden cardiac death most common manifestation and can often be first sign disease, especially young people. Correct stratification arrhythmic risk essential management these patients but remains challenge clinical cardiologist. In this context, aim our work was to review literature analyse important studies new developments...

10.3390/diagnostics15091149 article EN cc-by Diagnostics 2025-04-30

Background Persistent left ventricular (LV) systolic dysfunction in patients with acute lymphocytic myocarditis (LM) is widely unexplored. Objectives To assess the frequency and predictors of persistent LV LM reduced LVEF at admission. Methods results We retrospectively evaluated 89 consecutive histologically-proven enrolled three Italian referral hospitals. A subgroup 48 LM, baseline impairment an available echocardiographic assessment 12 months (6–18) from discharge constituted study...

10.1371/journal.pone.0214616 article EN cc-by PLoS ONE 2019-03-28

Objective To investigate whether parathyroidectomy (PTx) reverses risk factors for arrhythmias related to the QT dynamic changes evaluated during bicycle ergometry exercise test (ET). Methods Twenty-four postmenopausal women with primary hyperparathyroidism (PHPT) (mean age 60.0±8.4 years) and 30 sex- age-matched controls underwent ET, echocardiography, biochemical evaluation. The following stages were considered ET: rest, peak exercise, recovery. patients randomized two groups: 12 PTx...

10.1530/eje-13-0293 article EN European Journal of Endocrinology 2013-06-07

Abstract Background Hypercalcemia induces arrhythmias and shortening of QT . The aim this study was to investigate risk factors for occurrence in patients with primary hyperparathyroidism ( PHPT ) during bicycle ergometer exercise test ET ). Methods Thirty postmenopausal women (mean age, 60·9 ± 8·0 years) 30, sex age‐matched, controls underwent , echocardiogram mineral metabolism biochemical evaluation. following stages were considered : rest, peak exercise, recovery (early recovery, 2 10...

10.1111/eci.12038 article EN European Journal of Clinical Investigation 2012-11-30
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