Xiaodong Xu

ORCID: 0000-0003-3173-9601
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Research Areas
  • Reinforcement Learning in Robotics
  • Sports injuries and prevention
  • Shoulder Injury and Treatment
  • Educational Technology and Pedagogy
  • Robotic Path Planning Algorithms
  • Elbow and Forearm Trauma Treatment
  • Orthopedic Surgery and Rehabilitation
  • Tissue Engineering and Regenerative Medicine
  • Spine and Intervertebral Disc Pathology
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Medical Imaging and Analysis
  • Urological Disorders and Treatments
  • UAV Applications and Optimization
  • Periodontal Regeneration and Treatments
  • Cholesterol and Lipid Metabolism
  • Non-Invasive Vital Sign Monitoring
  • Endometriosis Research and Treatment
  • Antioxidant Activity and Oxidative Stress
  • Foot and Ankle Surgery
  • Retinoids in leukemia and cellular processes
  • Structural Behavior of Reinforced Concrete
  • Adaptive Dynamic Programming Control
  • Structural Engineering and Vibration Analysis
  • Hepatitis Viruses Studies and Epidemiology
  • Satellite Communication Systems

Lanzhou University
2025

Lanzhou University Second Hospital
2025

Central South University
2023-2024

Fujian Medical University
2020-2024

Union Hospital
2020-2024

China Mobile (China)
2024

Hangzhou Normal University
2022-2023

Tongji University
2022

Shanghai Tenth People's Hospital
2022

Huazhong University of Science and Technology
2020-2022

Alpha interferon (IFN-alpha) is an approved medication for chronic hepatitis B. Gamma (IFN-gamma) a key mediator of host antiviral immunity against B virus (HBV) infection in vivo. However, the molecular mechanism by which these cytokines suppress HBV replication remains elusive. Using immortalized murine hepatocyte (AML12)-derived cell line supporting tetracycline-inducible replication, we show this report that both IFN-alpha and IFN-gamma efficiently reduce amount intracellular...

10.1128/jvi.00918-10 article EN Journal of Virology 2010-07-08

Efficient delivery of bone morphogenetic protein-2 (BMP-2) with desirable bioactivity is still a great challenge in the field regeneration. In this study, silk fibroin/chitosan scaffold incorporated BMP-2-loaded mesoporous hydroxyapatite nanoparticles (mHANPs) was prepared (SCH-L). BMP-2 preloaded onto mHANPs high surface area before mixing composite. Bare (without BMP-2) fibroin/chitosan/mHANP (SCH) scaffolds and SCH directly absorbed (SCH-D) were investigated parallel for comparison. vitro...

10.1021/acsbiomaterials.9b01954 article EN ACS Biomaterials Science & Engineering 2020-03-19

Introduction Gallstones are a common digestive disorder, with global prevalence of 10%–15%, posing significant economic burden on public health. The formation gallstones is closely associated inflammation and nutritional status. Advanced Lung Cancer Inflammation Index (ALI) composite measure for assessing status; however, its relationship gallstone risk remains unclear. This study aims to investigate the association between ALI among U.S. adults. Methods based data from 2017–2020 National...

10.1371/journal.pone.0321733 article EN cc-by PLoS ONE 2025-04-15

Alzheimer's disease (AD) is one of the most common neurodegenerative diseases and manifests as progressive memory loss cognitive dysfunction. Neuroinflammation plays an important role in development anti-inflammatory drugs reduce risk disease. However, immune microenvironment brains patients with remains unclear, mechanisms by which improve have not been clearly elucidated. This study aimed to provide overview cell composition entorhinal cortex based on transcriptomes signature genes...

10.3389/fphar.2022.941656 article EN cc-by Frontiers in Pharmacology 2022-09-28

Endometrium is suspectable to severe injury due recurrent abortion, curettage or intrauterine infection which could lead pathological conditions and sabotage women's fertility. Promoting endometrium regeneration the core of treatments uterine related infertility. Patients who received traditional can only expect limited effects, thereby novel therapies are badly in need promote regeneration. Here we generated a decellularized extracellular matrix (ECM) from porcine dermis, composited adipose...

10.1016/j.mtbio.2023.100857 article EN cc-by-nc-nd Materials Today Bio 2023-11-15

Abstract Reinforcement learning (RL) has achieved remarkable advancements in navigation tasks recent years. However, tackling multi-goal with sparse rewards remains a complex and challenging problem due to the long-sequence decision-making involved. Such inherently incorporate hybrid action space, where robot needs select endpoint first before executing primitive actions. To address of rewards, we introduce novel hierarchical RL framework named Hierarchical Multi-Goal (HRL-MG). The main idea...

10.1007/s10462-024-10794-3 article EN cc-by Artificial Intelligence Review 2024-05-28

As drone technology rapidly evolves, the limitations of current communication systems, particularly regarding flight distance, bandwidth, and latency, become increasingly evident. This study addresses these challenges by integrating 5G with unmanned aerial vehicle (UAV) systems. Our approach employs a 300-meter network coupled an advanced onboard intelligent terminal, significantly improving communication. The paper details terminal's hardware software architecture, emphasizing enhancements...

10.1117/12.3038267 article EN 2024-08-22

Aiming at the difficulty in X ray diagnosis for sacroiliac joint's subluxation, joint images a patient's physiological state and pathological are analyzed this paper.We find that image of iliac pro-up shift 7mm is similar to pelvic rotation 10º around Y axis, external 5º pelvis Z axis.These results may easily lead massage doctor's misdiagnosis or leak-diagnosis.

10.2991/iiicec-15.2015.414 article EN cc-by-nc Advances in computer science research 2015-01-01

:Objective To investigatethe feasibility and superiority of combined spinal epidural anesthesia incesareansection.Methods 100 lying-in women who experienced cesarean section were collected anddivided into group(CSEA,n=50)and continuous epiduralanesthesia group(CEA,n=50).The change heart rate(HR),blood pressure(BP)and saturationof peripheral oxygen(SpO2),HR BP lyingin womeu in pre-anesthesia,5min,15minpost-anesthesia the time taking effect,time between beginning andlaboar newborn observed.The...

10.3760/cma.j.issn.1008-6706.2011.10.018 article EN Zhongguo jiceng yiyao 2011-05-15
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