Leoné Malan

ORCID: 0000-0003-3187-2410
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About
Contact & Profiles
Research Areas
  • Blood Pressure and Hypertension Studies
  • Heart Rate Variability and Autonomic Control
  • Cardiac Health and Mental Health
  • Cardiovascular Health and Disease Prevention
  • Stress Responses and Cortisol
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cardiovascular Disease and Adiposity
  • Adipokines, Inflammation, and Metabolic Diseases
  • Liver Disease Diagnosis and Treatment
  • Retinal Imaging and Analysis
  • Birth, Development, and Health
  • Hormonal Regulation and Hypertension
  • Cardiovascular Function and Risk Factors
  • Regulation of Appetite and Obesity
  • Nutritional Studies and Diet
  • Nutrition and Health in Aging
  • Obesity, Physical Activity, Diet
  • Diet and metabolism studies
  • Health and Well-being Studies
  • Cardiovascular and exercise physiology
  • Cardiovascular Health and Risk Factors
  • Sodium Intake and Health
  • Growth Hormone and Insulin-like Growth Factors
  • Acute Myocardial Infarction Research
  • Hormonal and reproductive studies

North-West University
2015-2024

University of Zurich
2022

University Hospital of Zurich
2022

South African Medical Research Council
2016-2020

St. Anne's University Hospital Brno
2016

Chinese Academy of Medical Sciences & Peking Union Medical College
2016

Jichi Medical University
2016

Masaryk University
2016

Medical Research Council
2015

University of Bern
2013

The Ambulatory blood pressure Registry TEleMonitoring of hypertension and cardiovascular rISk project was designed to set up an international registry including clinic (CBP) ambulatory (ABP) measurements in patients attending clinics all five continents, aiming assess different daily life types.Cross-sectional ABP, CBP demographic data, medical history risk profile were provided from existing databases by clinics. Hypertension types evaluated considering (≥140/90 mmHg) 24-h ABP (≥130/80...

10.1097/hjh.0000000000001074 article EN Journal of Hypertension 2016-08-11

Background Longitudinal cohort studies in sub-Saharan Africa are urgently needed to understand cardiovascular disease development. We, therefore, explored health behaviours and conventional risk factors of African individuals with optimal blood pressure (BP) (≤120/80 mm Hg), their 5-year prediction for the development hypertension. Methods The Prospective Urban Rural Epidemiology study North West Province, South Africa, started 2005 included volunteers (n = 1994; aged > 30 years) from a...

10.1093/ije/dys106 article EN International Journal of Epidemiology 2012-07-23

Adapting to an over-demanding stressful urban environment may exhaust the psychophysiological resources cope with these demands, and lead sympathetic nervous system dysfunction. The evidence that urban-dwelling lifestyle be detrimental cardiometabolic health of Africans motivated design Sympathetic activity Ambulatory Blood Pressure in African Prospective cohort study. We aimed determine neural mechanistic pathways involved emotional distress vascular remodelling. baseline sample included...

10.1093/ije/dyu199 article EN cc-by-nc International Journal of Epidemiology 2014-10-24

This study examined the association between nutritional awareness and diet quality, as indicated by energy density, dietary diversity adequacy to achieve recommendations, while considering potentially important role of socioeconomic status (SES). Data were derived from 1351 subjects, aged 18–69 years enrolled in ORISCAV-LUX study. Energy density score (EDS), (DDS) Recommendation Compliance Index (RCI) calculated based on data a food frequency questionnaire. Nutritional was defined...

10.3390/nu7042823 article EN Nutrients 2015-04-14

In Africans, arterial stiffness progression seems more pronounced compared to Caucasians. We the profiles of different age groups and focused on muscular arteries two central segments in African Caucasian people from South Africa. (N = 374) 376) participants (20–70 years), we measured carotid-radial (C-R) carotid-dorsalis pedis (C-DP) pulse wave velocity (PWV) aortic characteristic impedance (Zao). Major findings were that normotensive high-normal/hypertensive (HT) Caucasians indicated...

10.3109/10641963.2011.561897 article EN Clinical and Experimental Hypertension 2011-09-29

Background The Omron HEM-9000AI is the first automated tonometer to provide an estimate of central SBP (cSBP), which considered be more predictive cardiovascular events than brachial pressure. However, considerable differences between cSBP and that SphygmoCor have been reported, but not explained. This study assesses sources both estimates provides a handle on closest reality. Method For this purpose, aortic derived from calibrated carotid was used as device- algorithm-independent reference....

10.1097/hjh.0b013e328346a3bc article EN Journal of Hypertension 2011-04-26

The transition of sub-Saharan Africans from deep rural villages with traditional African lifestyles and diets to an urban westernized milieu, resulted in the prevalence hypertension, vascular disease, end points such as stroke, not just increase, 1 but be highest compared other ethnic groups. 2 This comes no surprise because poor cardiovascular health is a major problem Americans 3,4 who have been for much longer.][7] Despite this, there very little information on factors contributing this...

10.1038/ajh.2009.158 article EN American Journal of Hypertension 2009-09-03

Defensive active coping responses (being-in-control, acceptance of the stressor as reality) have been associated with vascular hyper-responsiveness in urban Africans. However, association between responses, blood pressure (BP), and ECG-derived left-ventricular hypertrophy (LVH) is unknown.Associations BP, silent ischaemia ECG Cornell product LVH were assessed 161 African Caucasian men identified by Amirkhan Coping Strategy Indicator. data obtained from 24-h ambulatory monitoring....

10.1097/hjh.0b013e32834fcf82 article EN Journal of Hypertension 2012-01-13

Various studies have shown that the relationship between waist circumference (WC) and abdominal obesity is age, gender as well ethnicity-dependent. WC criteria for Sub Saharan Africans not been defined by International Diabetes Federation (IDF). The aim was to determine which cut off best predicted Metabolic Syndrome (MetS) in a group of urban African teachers (80 males 93 females). We determined sphygmomanometer blood pressure, WC, glucose, high density lipoprotein cholesterol (HdL)...

10.1055/s-0031-1280801 article EN Experimental and Clinical Endocrinology & Diabetes 2011-11-01

The objective of this study was to make use a quantitative and qualitative approach comparing the systemic renin-angiotensin system (RAS) hypertensive black white African men by using RAS equilibrium analysis.This sub-study involved 23 (n = 15) 8) aged 39.5-41 years, living in North West Province South Africa. RAS-Fingerprinting determined with LC-MS/MS quantification angiotensin peptides. Blood pressure other variables were known methods.The main finding significant lower Ang I (<5.0 45.1...

10.1177/1470320316669880 article EN cc-by-nc Journal of the Renin-Angiotensin-Aldosterone System 2016-10-01

Spiritual coping has been defined as an individual's ability to utilise faith in God combined with certain Christian beliefs and religious practices appraise, understand, effectively cope stress. We aimed show the how specific spiritual strategies could be used assess handle chronic stress from a perspective amid ongoing coronavirus disease 2019 (COVID-19) pandemic beyond. A literature study was conducted identify positive negative during COVID-19 era highlighted adverse effects of...

10.4102/ids.v56i1.2823 article EN cc-by In die Skriflig/In Luce Verbi 2022-05-27
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