A5089724672- Dental materials and restorations
- Endodontics and Root Canal Treatments
- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Orthopaedic implants and arthroplasty
- Heavy Metal Exposure and Toxicity
- Photodynamic Therapy Research Studies
- Dental Erosion and Treatment
- Dental Radiography and Imaging
- Oral microbiology and periodontitis research
- Dental Research and COVID-19
- Mercury impact and mitigation studies
- Nanoparticles: synthesis and applications
- Laser Applications in Dentistry and Medicine
- Trace Elements in Health
- Corrosion Behavior and Inhibition
- Dental Anxiety and Anesthesia Techniques
- Tea Polyphenols and Effects
- Bone and Dental Protein Studies
- Redox biology and oxidative stress
- Animal testing and alternatives
- dental development and anomalies
- Cancer-related Molecular Pathways
- Bacterial biofilms and quorum sensing
- Medical and Biological Ozone Research
University of Washington
2009-2018
Smith College
2017-2018
Syracuse University
2017-2018
University of Memphis
2017-2018
Texas A&M University
2017-2018
Louisiana State University Health Sciences Center New Orleans
2017-2018
The University of Texas at San Antonio
2017-2018
University of Kentucky
2017-2018
University of Maryland, Baltimore County
2017-2018
Augusta University
2000-2014
Previous studies have shown a wide range of pulpal reactions to dentin bonding systems and poor correlation between in vitro vivo toxicity agents. Because agents are composed multiple components which may diffuse through dentin, we hypothesized that these cause cytotoxicity interactive (synergistic) effects. We investigated the cytotoxicities four components-HEMA, Bis-GMA, TEGDMA, UDMA-and effects for three binary combinations components-HEMA Bis-GMA TEGDMA UDMA. Cytotoxicities Balb/c 3T3...
There has been recent concern about the inadvertent exposure of dentin with patent tubules as well gingiva to bleaching systems containing 10-15% carbamide peroxide or 2-10% hydrogen for more than a few minutes. The aims present study were: (1) determine cytotoxicity dilutions in cell culture; (2) measure diffusion from agents through vitro; and (3) risk peroxide-induced these vital agents. 50% inhibitory dose (ID 50 ) succinyl dehydrogenase activity cultured cells was found be 0.58 mmol/L...
Abstract The aim of this study was to test the ability an infrared (IR) camera assess temperature changes and distributions in teeth below restorations when quartz‐tungsten‐halogen (QTH) light‐emitting diode (LED) curing lights were used photopolymerize restorative material. Our hypothesis that higher power density broader spectral distribution QTH source would cause greater increases tooth than LED source, these differences be best demonstrated with IR camera. Cavities prepared on human...
Abstract Aim To evaluate the long‐term sealing ability of four contemporary endodontic sealers [Pulp Canal Sealer (PCS), AH‐Plus, GuttaFlow and Epiphany] using a fluid filtration technique. Methodology The palatal roots 40 human maxillary molar teeth were selected root canal was prepared crown‐down technique (apical size 40, 6% taper). Roots irrigated with 3% NaOCl, 17% EDTA solution rinsed distilled water. Canals filled either PCS, or Epiphany single‐cone ( n = 8). Twenty‐four hours after...
Abstract Nickel has a number of adverse biological effects that have made the use nickel in biomedical implants controversial. Yet information about distribution tissues around nickel‐containing is scarce. The purpose current study was to laser ablation technique, combined with inductively coupled mass spectroscopy, assess spatial vivo . Polyethylene, pure wire, or alloy (Ni‐Cr) were implanted subcutaneously into rats for 7 days. analyzed Ni content and inflammation at 1‐mm intervals up 5 mm...
Only primary pulpal cell cultures and one virally transformed mouse culture have been formally reported in the literature to synthesize proteins such as phosphophoryn which are unique dentin matrix. In present study, a mixed was derived from dental papilla cells of 18-19 fetal day CD-1 mandibular first molars, maintained on 3T6 plating regimen, subsequently cloned after 28 passages. This line (MDPC-23) exhibited several features, some were characteristic odontoblasts viva The features this...
Green tea polyphenols (GTPPs) are considered beneficial to human health, especially as chemopreventive agents. Recently, cytotoxic reactive oxygen species (ROS) were identified in tumor and certain normal cell cultures incubated with high concentrations of the most abundant GTPP, (–)-epigallocatechin-3-gallate (EGCG). If EGCG also provokes production ROS epithelial cells, it may preclude topical use at higher doses. The current study examined oxidative status epithelial, salivary gland, oral...
Ten dental casting alloys were tested for alloy-element release into cell-culture medium, and this was related to alloy composition, microstructure, cytotoxicity (previously determined). Cell-culture medium analyzed elements by flame atomic absorption. Concentrations of in the normalized dividing them their abundance alloy, giving element medium-alloy ratios (EMA ratios). Results showed that Au, In, Pd generally did not dissolve but Ag, Cd, Cu, Ga, Ni, Zn frequently dissolved. Comparison EMA...
Abstract The in vitro cytotoxicity of nine metal cations common dental casting alloys was evaluated using Balb/c 3T3 fibroblasts and four toxicity parameters: total protein production, 3 H‐leucine incorporation, H‐thymidine MTT‐formazan production. Concentrations causing 50% compared to controls (TC50's) reversibility these effects were determined. range potency the 2–3 orders magnitude, with Cd 2+ showing greatest In 3+ least. Potency did not correlate atomic weight for metals. For each...
Nickel-containing alloys commonly are used in medical and dental applications that place them into long-term contact with soft tissues. The release of Ni ions from these is disturbing because the toxic, immunologic, carcinogenic effects have been documented for some compounds. In particular, solution recently shown to cause expression inflammatory mediators, such as interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), intercellular adhesion molecules (ICAMs) keratinocytes, monocytes,...